Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Roger Geertsema"'
Autor:
Allen Jankeel, Hawa Vahed, Pierre-Gregoire A Coulon, Ruchi Srivastava, Soumyabrata Roy, Ilhem Messaoudi, Lbachir BenMohamed, Cassandra Amezquita, Swayam Prakash, Nisha R Dhanushkodi, Roger Geertsema, Amanda M. Burkhardt, Lan Nguyen
Publikováno v:
Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
The nature of antiviral CD8+ T cells associated with protective and pathogenic herpes simplex virus type 1 (HSV-1) infections remains unclear. We compared the transcriptome, phenotype, and function of memory CD8+ T cells, sharing the same HSV-1 epito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e39b81096f3f2dc75a890c375e1d964
https://escholarship.org/uc/item/54v129gc
https://escholarship.org/uc/item/54v129gc
Autor:
Swayam, Prakash, Soumyabrata, Roy, Ruchi, Srivastava, Pierre-Gregoire, Coulon, Nisha R, Dhanushkodi, Hawa, Vahed, Allen, Jankeel, Roger, Geertsema, Cassandra, Amezquita, Lan, Nguyen, Ilhem, Messaoudi, Amanda M, Burkhardt, Lbachir, BenMohamed
Publikováno v:
Scientific Reports
The nature of antiviral CD8+ T cells associated with protective and pathogenic herpes simplex virus type 1 (HSV-1) infections remains unclear. We compared the transcriptome, phenotype, and function of memory CD8+ T cells, sharing the same HSV-1 epito
Autor:
Nisha R Dhanushkodi, Soumyabrata Roy, Vivianna Nguyen, Roger Geertsema, Lbachir BenMohamed, Nuha I. Alomari, Ruchi Srivastava, Swayam Prakash, Cynthia Lam, Angela M. Nguyen, Wasay R. Warsi, Pierre-Gregoire A Coulon, Stephanie Salazar, Elyssa Gorospe
Publikováno v:
Journal of virology, vol 93, iss 18
Chronic viruses such as herpes simplex virus 1 (HSV-1) evade the hosts’ immune system by inducing the exhaustion of antiviral T cells. In the present study, we found that exhausted HSV-specific CD8(+) T cells, with elevated expression of programmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237cff6702e212cf24e4cad714ed9ab6
https://escholarship.org/uc/item/7c33m4nx
https://escholarship.org/uc/item/7c33m4nx
Autor:
Ruchi Srivastava, Nicolas N. Ong, Anthony B. Nesburn, Lbachir BenMohamed, Sravya Chilukuri, Xavier Dervillez, Arif A. Khan, Rasha E. Afifi, Aziz Alami Chentoufi, Nelson Osorio, Roger Geertsema, Nora Shukr, Yasmin Fazli, Steven L. Wechsler
Publikováno v:
Journal of Virology. 90:3913-3928
Persistent pathogens, such as herpes simplex virus 1 (HSV-1), have evolved a variety of immune evasion strategies to avoid being detected and destroyed by the host's immune system. A dynamic cross talk appears to occur between the HSV-1 latency-assoc
Autor:
Soumyabrata Roy, Cynthia Lam, Hawa Vahed, Sager S. Walia, Lbachir BenMohamed, Undariya Boldbaatar, Anthony Lou, Vivianna Nguyen, Grace J. Kim, Roger Geertsema, Taikun Yamada, Vincent T. Ly, Mona A. Fouladi, Arif A. Khan, Nigel W Fraser, Ruchi Srivastava
Publikováno v:
Journal of Virology. 92
Herpes simplex virus 1 (HSV-1) is a prevalent human pathogen that infects the cornea, causing potentially blinding herpetic disease. A clinical herpes vaccine is still lacking. In the present study, a novel prime/pull vaccine was tested in a human le
Autor:
Arif A, Khan, Ruchi, Srivastava, Hawa, Vahed, Soumyabrata, Roy, Sager S, Walia, Grace J, Kim, Mona A, Fouladi, Taikun, Yamada, Vincent T, Ly, Cynthia, Lam, Anthony, Lou, Vivianna, Nguyen, Undariya, Boldbaatar, Roger, Geertsema, Nigel W, Fraser, Lbachir, BenMohamed
Publikováno v:
Journal of virology. 92(16)
There is an urgent need for a vaccine against widespread herpes simplex virus infections. The present study demonstrates that immunization of HLA transgenic rabbits with a peptide/CXCL10 prime/pull vaccine triggered mobilization of HSV-specific CD8+
Autor:
Nhi Thi Uyen Thai, Mina Kalantari, Nelson Osorio, Gargi Dasgupta, Ruchi Srivastava, Aziz Alami Chentoufi, Arif A. Khan, Steven L. Wechsler, Anthony B. Nesburn, Lbachir BenMohamed, Roger Geertsema
Publikováno v:
Journal of Virology. 89:6619-6632
Most blinding ocular herpetic disease is due to reactivation of herpes simplex virus 1 (HSV-1) from latency rather than to primary acute infection. No herpes simplex vaccine is currently available for use in humans. In this study, we used the HLA-A*0
Autor:
Xianzhi Jiang, Nelson Osorio, Lbachir BenMohamed, Guey Chuen Perng, Roger Geertsema, Chinhui Hsiang, Donald J. Brown, Steven L. Wechsler
Publikováno v:
Current eye research, vol 41, iss 3
AimRecurrent herpetic stromal keratitis (rHSK), due to an immune response to reactivation of herpes simplex virus (HSV-1), can cause corneal blindness. The development of therapeutic interventions such as drugs and vaccines to decrease rHSK have been