Výsledky vyhledávání - "Roger G. Dean"

Ultrasensitive Detection of Chemical Substances

Autor: Roger G. Dean

During the past quarter, we have produced and cloned several hybridomas with antibody against AChE or AChE-DFP conjugate. One of these antibodies, designed V16-6B, has special interest. As expected this antibody binds the AChE-DFP conjugate effective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d16f524f19f53557958a28b57315c67
https://doi.org/10.21236/ada129494

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Absence of significant age-dependent increase of single-stranded DNA extracted from mouse liver nuclei

Autor: Richard G. Cutler, Roger G. Dean

Publikováno v: Experimental gerontology. 13(5)

Possible age-dependent accumulation of physico-chemical changes in purified mouse liver DNA was investigated. Previous reports of another laboratory (Chetsanga et al. , 1977) have indicated the presence and substantial age-dependent increase in the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df247894b5383a0f189292836fa64587
https://pubmed.ncbi.nlm.nih.gov/738375

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Sister-chromatid exchange induction by carcinogens in HTC cells: an in vitro system which does not require addition of activating factors

Autor: David Kram, Edward L. Schneider, Gaither D. Bynum, Roger G. Dean

Publikováno v: Mutation research. 74(6)

The hepatic tumor cell line (HTC) was tested for the ability to produce sister chromatid exchanges (SCEs) in response to chemical carcinogens which require activation. Without the addition of exogenous microsomal enzyme preparations, cyclophosphamide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a03ab20d4169c874dd1507e34d4dd91
https://pubmed.ncbi.nlm.nih.gov/7464852

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Effects of acute and chronic administration of mitomycin C on the induction of sister chromatid exchanges in vivo

Autor: David Kram, William H. Farland, Roger G. Dean, Edward L. Schneider, Gaither D. Bynum, Jerry R. Williams

Publikováno v: Environmental mutagenesis. 3(4)

Frequencies of sister chromatid exchanges (SCE) were analyzed in bone marrow cells of mice injected with mitomycin C (MMC) both before and during infusion with bromodeoxyuridine (BrdU). Administration of MMC at 1, 6.5, and 13 hours after the onset of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944e7f62e6f8f6ea05bf0349bff66837
https://pubmed.ncbi.nlm.nih.gov/7262057

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