Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Roger Ferrini"'
Autor:
Wafik S. El-Deiry, Anke Kretz-Rommel, Mark W. Renshaw, Bing Lin, Daniela I. Oltean, Elise Chen, Glenda Batzer, David T. Dicker, Roger Ferrini, Joshua E. Allen
PDF file, 55K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a723150c3587d794fbec12cd2e11b26
https://doi.org/10.1158/1535-7163.22498630
https://doi.org/10.1158/1535-7163.22498630
Autor:
Wafik S. El-Deiry, Anke Kretz-Rommel, Mark W. Renshaw, Bing Lin, Daniela I. Oltean, Elise Chen, Glenda Batzer, David T. Dicker, Roger Ferrini, Joshua E. Allen
PDF file, 30K, Combining DR4 Atrimer� complexes with TRAIL. Sub-G1 content in HCT116 cells treated with 1G2 (50 ng/mL) or TRAIL (25 ng/mL) for 24 hours (n=2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aec55db41d0b645a001665ef7bf4414
https://doi.org/10.1158/1535-7163.22498627.v1
https://doi.org/10.1158/1535-7163.22498627.v1
Autor:
Wafik S. El-Deiry, Anke Kretz-Rommel, Mark W. Renshaw, Bing Lin, Daniela I. Oltean, Elise Chen, Glenda Batzer, David T. Dicker, Roger Ferrini, Joshua E. Allen
PDF file, 84K, Excess soluble DR4, but not DR5, blocks the cytotoxic effect of agonist DR4 Atrimer � complexes. Atrimer� complex 1C9 was pre-incubated with or without soluble DR4-Fc or DR5-Fc for 1 hour before addition to Colo205 cells. Cell viab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ef4794f5e22d762f4191328271729b
https://doi.org/10.1158/1535-7163.22498636.v1
https://doi.org/10.1158/1535-7163.22498636.v1
Autor:
Wafik S. El-Deiry, Anke Kretz-Rommel, Mark W. Renshaw, Bing Lin, Daniela I. Oltean, Elise Chen, Glenda Batzer, David T. Dicker, Roger Ferrini, Joshua E. Allen
TRAIL is a trimeric protein that potently induces apoptosis in cancer cells by binding to the trimeric death receptors (DR4 or DR5). Death receptors are attractive therapeutic targets through both the recombinant TRAIL ligand as well as receptor agon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25f5e28da9fa0e6dfc20402ad09173e
https://doi.org/10.1158/1535-7163.c.6535933
https://doi.org/10.1158/1535-7163.c.6535933
Autor:
Wafik S. El-Deiry, Anke Kretz-Rommel, Mark W. Renshaw, Bing Lin, Daniela I. Oltean, Elise Chen, Glenda Batzer, David T. Dicker, Roger Ferrini, Joshua E. Allen
PDF file, 80K, Schematic representation of different library designs for primary and affinity matured selections. The native sequence of the tetranectin loop regions is shown at the top. Alterations in the primary and affinity maturation libraries ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd32bfb5c463df5b9b07f7c434f2af8
https://doi.org/10.1158/1535-7163.22498651.v1
https://doi.org/10.1158/1535-7163.22498651.v1
Autor:
Wafik S. El-Deiry, Anke Kretz-Rommel, Mark W. Renshaw, Bing Lin, Daniela I. Oltean, Elise Chen, Glenda Batzer, David T. Dicker, Roger Ferrini, Joshua E. Allen
PDF file, 55K, Surface DR4 knockdown. Surface DR4 by flow cytometry in HCT116 cells transfected with a scramble control or DR4 siRNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c499c2c47bd3b88769bfa1add1b35d
https://doi.org/10.1158/1535-7163.22498639.v1
https://doi.org/10.1158/1535-7163.22498639.v1
Autor:
Wafik S. El-Deiry, Anke Kretz-Rommel, Mark W. Renshaw, Bing Lin, Daniela I. Oltean, Elise Chen, Glenda Batzer, David T. Dicker, Roger Ferrini, Joshua E. Allen
PDF file, 157K, Representative example of screening affinity matured Atrimer� complexes. Single point cytotoxicity assays (A) we performed with 293 PEAK supernatants at 1:2 and 1:10 dilution using the Vialight Plus kit and compared to previously id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc553fc46c7665711695d41d91d4493
https://doi.org/10.1158/1535-7163.22498648.v1
https://doi.org/10.1158/1535-7163.22498648.v1
Autor:
Wafik S. El-Deiry, Anke Kretz-Rommel, Mark W. Renshaw, Bing Lin, Daniela I. Oltean, Elise Chen, Glenda Batzer, David T. Dicker, Roger Ferrini, Joshua E. Allen
PDF file, 63K, Combining DR4 Atrimer� complexes with TRAIL. Sub-G1 content in HCT116 cells treated with 1G2 (50 ng/mL) or TRAIL (25 ng/mL) for 24 hours (n=2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa17c364ed0b09ec629952056d91a5a2
https://doi.org/10.1158/1535-7163.22498633.v1
https://doi.org/10.1158/1535-7163.22498633.v1
Autor:
Wafik S. El-Deiry, Anke Kretz-Rommel, Mark W. Renshaw, Bing Lin, Daniela I. Oltean, Elise Chen, Glenda Batzer, David T. Dicker, Roger Ferrini, Joshua E. Allen
PDF file, 53K, TRAIL-receptor expression in SW620 and HCT15 cell lines. Western blot analysis of TRAIL receptors in SW620 and HCT15 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55597d981af7535d555695576c0f5b52
https://doi.org/10.1158/1535-7163.22498642.v1
https://doi.org/10.1158/1535-7163.22498642.v1
Publikováno v:
Cell, Vol. 133, No 4 (2008) pp. 681-692
The killer lymphocyte protease granzyme A (GzmA) triggers caspase-independent target cell death with morphological features of apoptosis. We previously showed that GzmA acts directly on mitochondria to generate reactive oxygen species (ROS) and disru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1a800870ab0b7c94ee3682c5477dbc
