Výsledky vyhledávání - "Roger E. Ganschow"

Characterization of a murine cDNA encoding a member of the carboxylesterase multigene family

Autor: Dennis A. Stephenson, Katherine Tepperman, Roger E. Ganschow, Stephen G. Grant, Sukumar Medda, Mariana Ovnic, Rosemary W. Elliott

Publikováno v: Genomics. 9(2)

We have characterized a mRNA sequence containing the entire coding region of a mouse carboxylesterase (EC 3.1.1.1). pEs-N, an 1840-bp composite of five overlapping cDNA clones, contains an open reading frame of 554 amino acids that display a high deg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cda3935823f46194fd474cce1723567
https://pubmed.ncbi.nlm.nih.gov/1840565

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DNA sequence variation within the β-glucuronidase gene complex among inbred strains of mice

Autor: Rosemary W. Elliott, Colleen Hohman, S.Diane Lund, Roger E. Ganschow, Melanie A. D'Amore, Thomas R. Korfhagen, Patricia M. Gallagher, Joanne Pazik

Publikováno v: Genomics. 1:145-152

Tightly linked to the gene that encodes murine β-glucuronidase (GUS) are three GUS-specific regulatory elements. Together, these elements define the GUS gene complex. Specific alleles of each regulatory element are associated with a specific GUS str

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbaba55bf5ef3d76302759e31c3d1d0
https://doi.org/10.1016/0888-7543(87)90006-1

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APPARENT TRANS CONTROL OF MURINE βGLUCURONIDASE SYNTHESIS BY A TEMPORAL GENETIC ELEMENT

Autor: Susan A. Meredith, Roger E. Ganschow

Publikováno v: Genetics. 90:725-734

A difference in the heat-inactivation kinetics between the P-glucuronidases of C3HeB/FeJ and C57B1/6J mice was utilized to assess the mode of action of a temporal genetic element in controlling the expression of the P-glucuronidase structural gene Gu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f29a877bec18327e31cabbd5ece9b13
https://doi.org/10.1093/genetics/90.4.725

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Genetic control of levels of murine kidney glucuronidase mRNA in response to androgen

Autor: R Palmer, Roger E. Ganschow, P M Gallagher, W L Boyko

Publikováno v: Proceedings of the National Academy of Sciences. 80:7596-7600

A cis-acting genetic element, designated Gus-r, regulates the androgen-induced rates of murine glucuronidase (EC 3.2.1.31) synthesis in kidney tubule cells and is tightly linked to the glucuronidase structural gene, Gus-s. To investigate the molecula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ecb66585846026933cd9a998281078
https://doi.org/10.1073/pnas.80.24.7596

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Genetic variation of milk proteins in mice

Autor: Roger E. Ganschow, John E. Piletz

Publikováno v: Biochemical Genetics. 19:1023-1030

A survey for qualitative and quantitative variation in milk proteins from 58 inbred strains of mice revealed two electrophoretic variants. One is in a whey acidic protein of milk of YBR mice and the other is in a curd protein of the Asian house mouse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7423d5280515430de680e6da229a5f70
https://doi.org/10.1007/bf00504265

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The molecular genetics of mammalian glucuronidase

Autor: Kenneth Paigen, Shiro Tomino, Richard T. Swank, Roger E. Ganschow

Publikováno v: Journal of Cellular Physiology. 85:379-392

The genetic factors known to be involved in the final realization of beta-glucuronidase activity in mice are considered from the standpoint of structural genes determining the catalytic activity of enzyme molecules as well as the recognition features

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbab072d326d13c4adf02f123a636ed4
https://doi.org/10.1002/jcp.1040850406

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Overlapping transcriptional units on the same strand within the murine beta-glucuronidase gene complex

Autor: J. Mcneish, Roger E. Ganschow, Bin Wang, Thomas R. Korfhagen, M. A. D'amore, S. Steven Potter, Patricia M. Gallagher

Publikováno v: Journal of Biological Chemistry. 263:15841-15844

We have identified and partially characterized a complex transcriptional unit within the murine beta-glucuronidase gene complex on chromosome 5. On the same strand and within the first intron of the beta-glucuronidase structural gene, Gus-s, we obser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::984939030a3c40aceb75d3618c6f9049
https://doi.org/10.1016/s0021-9258(18)37522-7

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Zinc and Copper in Milk and Tissues of Nursing Lethal Milk Mutant Mice

Autor: Harvey R. Herschman, Bo Lönnerdal, John E. Piletz, Wade L. Berry, Lucille S. Hurley, Roger E. Ganschow

Publikováno v: The Journal of Nutrition. 117:83-90

Zinc concentration was lower in liver of suckling 1-d-old lethal milk (lm/lm) mutant mice than in wild-type pups, in accordance with the hypothesis of milk-induced zinc deficiency previously proposed to underlie this mutation. Despite the initial def

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181495f25a4d62fceb9229706b6d1196
https://doi.org/10.1093/jn/117.1.83

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The complete nucleotide sequence of murine β-glucuronidase mRNA and its deduced polypeptide

Autor: Patricia M. Gallagher, S.Diane Lund, Roger E. Ganschow, Melanie A. D'Amore

Publikováno v: Genomics. 2:215-219

The complete nucleotide sequence of murine β-glucuronidase (GUS) mRNA has been compiled from three overlapping cloned cDNAs and a single GUS-specific genomic clone. The sequence is composed of 2455 nucleotides, exclusive of the poly(A) tail. The 5�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6fabb815bc4571bf3e268367e1aefb
https://doi.org/10.1016/0888-7543(88)90005-5

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