Zobrazeno 1 - 10
of 37 255
pro vyhledávání: '"Roger D"'
Autor:
Katharina Kusejko, Roger D. Kouyos, Enos Bernasconi, Katia Boggian, Dominique L. Braun, Alexandra Calmy, Matthias Cavassini, Christian van Delden, Hansjakob Furrer, Christian Garzoni, Hans H. Hirsch, Cedric Hirzel, Oriol Manuel, Patrick Schmid, Nina Khanna, Fadi Haidar, Marco Bonani, Dela Golshayan, Michael Dickenmann, Daniel Sidler, Aurelia Schnyder, Nicolas J. Mueller, Huldrych F. Günthard, Peter W. Schreiber, the Swiss HIV Cohorts Study and the Swiss Transplant Cohort Study
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Since the implementation of universal antiretroviral therapy, kidney transplantation (K-Tx) has become a valuable option for treatment of end-stage kidney disease for people with HIV (PWH) with similar patient and graft survival a
Externí odkaz:
https://doaj.org/article/767aac18d19743259b911d3faa36bd3c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The oxalate-carbonate pathway (OCP) involves degradation of soil oxalate to carbonate. To exploit and manage this natural mineralization of assimilated atmospheric CO2 into stable carbonates, improved understanding of this complex biotransfo
Externí odkaz:
https://doaj.org/article/e6ecd1b362e8400eae75f0dc38ace514
Autor:
Anthony M. Baudino, Harris F. Ciaccio, Michael J. Turski, Xavier A. Akins, Phoebus Sun Cao, Elisa Morales, Roger D. Sommer, Adam R. Johnson, Donald J. Wink, Kyle A. Grice, Kari L. Stone
Publikováno v:
Foundations, Vol 4, Iss 3, Pp 362-375 (2024)
Zinc is integral to diverse biological functions, acting catalytically, structurally, and supportively in essential enzyme cycles, despite its limited amounts in the body. Targeting zinc enzymes with potent drugs, such as Vorinostat, demonstrates the
Externí odkaz:
https://doaj.org/article/858b2f61f78e4bf4b6c49765069f8bc9
Publikováno v:
Machine Learning and Knowledge Extraction, Vol 6, Iss 3, Pp 1798-1817 (2024)
In medicine, dynamic treatment regimes (DTRs) have emerged to guide personalized treatment decisions for patients, accounting for their unique characteristics. However, existing methods for determining optimal DTRs face limitations, often due to reli
Externí odkaz:
https://doaj.org/article/777d818e90b34b589d3ffecd785054c2
Autor:
Burcu Tepekule, Lisa Jörimann, Corinne D. Schenkel, Lennart Opitz, Jasmin Tschumi, Rebekka Wolfensberger, Kathrin Neumann, Katharina Kusejko, Marius Zeeb, Lucas Boeck, Marisa Kälin, Julia Notter, Hansjakob Furrer, Matthias Hoffmann, Hans H. Hirsch, Alexandra Calmy, Matthias Cavassini, Niklaus D. Labhardt, Enos Bernasconi, Gabriela Oesch, Karin J. Metzner, Dominique L. Braun, Huldrych F. Günthard, Roger D. Kouyos, Fergal Duffy, Johannes Nemeth
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111228- (2024)
Summary: In people with HIV-1 (PWH), Mycobacterium tuberculosis (MTB) infection poses a significant threat. While active tuberculosis (TB) accelerates immunodeficiency, the interaction between MTB and HIV-1 during asymptomatic phases remains unclear.
Externí odkaz:
https://doaj.org/article/9a0f0af5bac64596afefb67ddc130c6e
Autor:
Giovanni S. Offeddu, Elena Cambria, Sarah E. Shelton, Kristina Haase, Zhengpeng Wan, Luca Possenti, Huu Tuan Nguyen, Mark R. Gillrie, Dean Hickman, Charles G. Knutson, Roger D. Kamm
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Desmoplasia in breast cancer leads to heterogeneity in physical properties of the tissue, resulting in disparities in drug delivery and treatment efficacy among patients, thus contributing to high disease mortality. Personalized in vitro bre
Externí odkaz:
https://doaj.org/article/a394968a50cf4ecb907cb7897f5472c7
Autor:
Magdalena Schwarzmüller, Cristina Lozano, Merle Schanz, Irene A. Abela, Silvan Grosse-Holz, Selina Epp, Martina Curcio, Jule Greshake, Peter Rusert, Michael Huber, Roger D. Kouyos, Huldrych F. Günthard, Alexandra Trkola
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101702- (2024)
Summary: The development of broadly neutralizing antibody (bnAb)-based therapeutic HIV-1 vaccines and cure concepts depends on monitoring bnAb plasma activity in people with HIV (PWH) on suppressive antiretroviral therapy (ART). To enable this, analy
Externí odkaz:
https://doaj.org/article/a726c3b8bb5347b0a26db15a5cdb413e
Publikováno v:
Ecological Indicators, Vol 166, Iss , Pp 112407- (2024)
Understanding how human activities are altering landscapes is critical to address habitat loss and biodiversity decline. Cumulative pressure mapping has emerged as a tool to quantify both the extent and intensity of multiple forms of human activities
Externí odkaz:
https://doaj.org/article/5fb853bbce914bfd8565504582e15108
Publikováno v:
The Ultrasound Journal, Vol 16, Iss 1, Pp 1-6 (2024)
Abstract Background Point-of-care ultrasound (POCUS) has become a mainstay in the evaluation of critically ill patients in the intensive care unit (ICU). ECMO patients are susceptible to complications during prolonged ICU stay, including cannula malp
Externí odkaz:
https://doaj.org/article/0fe627e46f534b6d872369a8d205d6d2
Autor:
Nadia Neuner-Jehle, Marius Zeeb, Christian W Thorball, Jacques Fellay, Karin J Metzner, Paul Frischknecht, Kathrin Neumann, Christine Leeman, Andri Rauch, Marcel Stöckle, Michael Huber, Matthieu Perreau, Enos Bernasconi, Julia Notter, Matthias Hoffmann, Karoline Leuzinger, Huldrych F Günthard, Chloé Pasin, Roger D Kouyos, Swiss HIV Cohort Study (SHCS)
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012385 (2024)
The pathogenesis of HIV-1 infection is governed by a highly dynamic, time-dependent interaction between the host and the viral genome. In this study, we developed a novel systematic approach to assess the host-virus interaction, using average pairwis
Externí odkaz:
https://doaj.org/article/4c8bd76294a344a5a8d9bd33b496838f