Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Roger Chung"'
Autor:
Stephanie L. Rayner, Alison Hogan, Jennilee M. Davidson, Tyler Chapman, Flora Cheng, Luan Luu, Sharlynn Wu, Selina Zhang, Shu Yang, Ian Blair, Marco Morsch, Roger Chung, Albert Lee
Publikováno v:
Neurobiology of Disease, Vol 192, Iss , Pp 106421- (2024)
Previously, we demonstrated that the SCFcyclin F complex directly mediates the poly-ubiquitylation of TDP-43, raising the question of whether cyclin F can be used to enhance the turnover of TDP-43. A hurdle to the use of cyclin F, however, is that th
Externí odkaz:
https://doaj.org/article/938a323b072b422dbb397509b51afada
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/992c64de405c42a4adb44c9d55eb58ca
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/08d430aa77914843898d41157b9d9380
Autor:
Stephanie L. Rayner, Shu Yang, Natalie E. Farrawell, Cyril J. Jagaraj, Flora Cheng, Jennilee M. Davidson, Luan Luu, Alberto G. Redondo, Alberto Rábano, Daniel Borrego-Hernández, Julie D. Atkin, Marco Morsch, Ian P. Blair, Justin J. Yerbury, Roger Chung, Albert Lee
Publikováno v:
Neurobiology of Disease, Vol 167, Iss , Pp 105673- (2022)
Background: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by the loss of upper and lower motor neurons in the brain and spinal cord. ALS and frontotemporal dementia (FTD) are overlapping diseases with shared p
Externí odkaz:
https://doaj.org/article/8b0375252ae3453588b0ea1234e98d29
Autor:
Vivek Gupta, Mehdi Mirzaei, Veer Bala Gupta, Nitin Chitranshi, Yogita Dheer, Roshana Vander Wall, Mojdeh Abbasi, Yuyi You, Roger Chung, Stuart Graham
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Abstract Neuroserpin is a serine protease inhibitor that regulates the activity of plasmin and its activators in the neuronal tissues. This study provides novel evidence of regulatory effect of the neuroserpin on plasmin proteolytic activity in the r
Externí odkaz:
https://doaj.org/article/e9b70b9ed1e54766a0cc9a682a0c7d4e
Autor:
Kathryn Goozee, Pratishtha Chatterjee, Ian James, Kaikai Shen, Hamid R. Sohrabi, Prita R. Asih, Preeti Dave, Bethany Ball, Candice ManYan, Kevin Taddei, Roger Chung, Manohar L. Garg, Ralph N. Martins
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Brain and blood fatty acids (FA) are altered in Alzheimer’s disease and cognitively impaired individuals, however, FA alterations in the preclinical phase, prior to cognitive impairment have not been investigated previously. The current st
Externí odkaz:
https://doaj.org/article/5fb81ae1caec4113ad4d2005ed84ba84
Publikováno v:
Scientific Reports, Vol 6, Iss 1, Pp 1-11 (2016)
Abstract Gene therapies represent a promising therapeutic route for liver cancers, but major challenges remain in the design of safe and efficient gene-targeting delivery systems. For example, cationic polymers show good transfection efficiency as ge
Externí odkaz:
https://doaj.org/article/d1d01828b5e14bf0af99b27c0eb88f13
Autor:
Wei Wu, Joseph A Nicolazzo, Li Wen, Roger Chung, Roger Stankovic, Shisan S Bao, Chai K Lim, Bruce J Brew, Karen M Cullen, Gilles J Guillemin
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59749 (2013)
To assess the role of the kynurenine pathway in the pathology of Alzheimer's disease (AD), the expression and localization of key components of the kynurenine pathway including the key regulatory enzyme tryptophan 2,3 dioxygenase (TDO), and the metab
Externí odkaz:
https://doaj.org/article/c69cbd3ce9a345eab273769269126948
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14123 (2010)
Astrocytes have long been perceived only as structural and supporting cells within the central nervous system (CNS). However, the discovery that these glial cells may potentially express receptors capable of responding to endogenous neurotransmitters
Externí odkaz:
https://doaj.org/article/6615200495244446b1a7e848f5274e08
Autor:
Rowan A. W. Radford, Stephanie L. Rayner, Paulina Szwaja, Marco Morsch, Flora Cheng, Tianyi Zhu, Jocelyn Widagdo, Victor Anggono, Dean L. Pountney, Roger Chung, Albert Lee
Publikováno v:
Journal of Neurochemistry. 165:563-586
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31b317f45107bb5a8d7a6fddc10112fe
https://doi.org/10.1111/jnc.15796
https://doi.org/10.1111/jnc.15796