Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Roger C, Hardie"'
A Single Residue Mutation in the Gαq Subunit of the G Protein Complex Causes Blindness in Drosophila
Autor:
Jinguo Cao, Murali K. Bollepalli, Yuhui Hu, Jin Zhang, Qiang Li, Hongmei Li, Hua Chang, Feng Xiao, Roger C. Hardie, Yikang S. Rong, Wen Hu
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 1, Pp 363-371 (2018)
Heterotrimeric G proteins play central roles in many signaling pathways, including the phototransduction cascade in animals. However, the degree of involvement of the G protein subunit Gαq is not clear since animals with previously reported strong l
Externí odkaz:
https://doaj.org/article/5e1c027e9e414dabbde1af7bf92904f3
Autor:
Mikko Juusola, An Dau, Zhuoyi Song, Narendra Solanki, Diana Rien, David Jaciuch, Sidhartha Anil Dongre, Florence Blanchard, Gonzalo G de Polavieja, Roger C Hardie, Jouni Takalo
Publikováno v:
eLife, Vol 6 (2017)
Small fly eyes should not see fine image details. Because flies exhibit saccadic visual behaviors and their compound eyes have relatively few ommatidia (sampling points), their photoreceptors would be expected to generate blurry and coarse retinal im
Externí odkaz:
https://doaj.org/article/723554c067f744979d9da6f89f9c889f
Autor:
Joni Kemppainen, Ben Scales, Keivan Razban Haghighi, Jouni Takalo, Neveen Mansour, James McManus, Gabor Leko, Paulus Saari, James Hurcomb, Andra Antohi, Jussi-Petteri Suuronen, Florence Blanchard, Roger C. Hardie, Zhuoyi Song, Mark Hampton, Marina Eckermann, Fabian Westermeier, Jasper Frohn, Hugo Hoekstra, Chi-Hon Lee, Marko Huttula, Rajmund Mokso, Mikko Juusola
Publikováno v:
'Proceedings of the National Academy of Sciences of the USA ', vol: 119, pages: e2109717119-1-e2109717119-12 (2022)
Proceedings of the National Academy of Sciences of the United States of America 119(12), e2109717119 (2022). doi:10.1073/pnas.2109717119
Proceedings of the National Academy of Sciences of the United States of America 119(12), e2109717119 (2022). doi:10.1073/pnas.2109717119
Proceedings of the National Academy of Sciences of the United States of America 119(12), e2109717119 (2022). doi:10.1073/pnas.2109717119
Neural mechanisms behind stereopsis, which requires simultaneous disparity inputs from two eyes, have remain
Neural mechanisms behind stereopsis, which requires simultaneous disparity inputs from two eyes, have remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d409581362cb1e8fc1a47b18a8787d7d
https://eprints.whiterose.ac.uk/184979/1/pnas.2109717119.pdf
https://eprints.whiterose.ac.uk/184979/1/pnas.2109717119.pdf
Autor:
Joni, Kemppainen, Ben, Scales, Keivan, Razban Haghighi, Jouni, Takalo, Neveen, Mansour, James, McManus, Gabor, Leko, Paulus, Saari, James, Hurcomb, Andra, Antohi, Jussi-Petteri, Suuronen, Florence, Blanchard, Roger C, Hardie, Zhuoyi, Song, Mark, Hampton, Marina, Eckermann, Fabian, Westermeier, Jasper, Frohn, Hugo, Hoekstra, Chi-Hon, Lee, Marko, Huttula, Rajmund, Mokso, Mikko, Juusola
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(12)
SignificanceTo move efficiently, animals must continuously work out their x,y,z positions with respect to real-world objects, and many animals have a pair of eyes to achieve this. How photoreceptors actively sample the eyes' optical image disparity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2e59412a3da4db37b3074abbe5a3cce
https://pubmed.ncbi.nlm.nih.gov/35298337
https://pubmed.ncbi.nlm.nih.gov/35298337
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157993 (2016)
More than five decades ago it was postulated that sensory neurons detect and selectively enhance behaviourally relevant features of natural signals. Although we now know that sensory neurons are tuned to efficiently encode natural stimuli, until now
Externí odkaz:
https://doaj.org/article/db81c747ff8844c59623b835c484bfd5
Autor:
Sidhartha Dongre, Mikko Juusola, David Jaciuch, Xiaofeng Li, Diana Rien, Murali K. Bollepalli, Brian Chu, Zhuoyi Song, Lei Zheng, Roger C. Hardie, Patrick J. Dolph, Florence Blanchard, Anton Nikolaev, Ahmad N. Abou Tayoun, An Dau
Publikováno v:
The Journal of Neuroscience. 39:7132-7154
Ca2+-activated K+ channels (BK and SK) are ubiquitous in synaptic circuits, but their role in network adaptation and sensory perception remains largely unknown. Using electrophysiological and behavioral assays and biophysical modeling, we discover ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::503dbf41918ebb73eb20a4eb02b777f5
https://doi.org/10.1523/jneurosci.3213-18.2019
https://doi.org/10.1523/jneurosci.3213-18.2019
Autor:
Jouni Takalo, James Hurcomb, Jasper Frohn, Chi-Hon Lee, Paulus Saari, Andra Antohi, Rajmund Mokso, Marko Huttula, Keivan Razban Haghighi, Zhuoyi Song, Mikko Juusola, Neveen Mansour, Fabian Westermeier, James McManus, Jussi-Petteri Suuronen, Mark Hampton, Marina Eckermann, Gábor Lékó, Hugo Hoekstra, Roger C. Hardie, Florence Blanchard, Joni Kemppainen, Ben Scales
Neural mechanisms behind stereopsis, which requires simultaneous disparity inputs from two eyes, have remained mysterious. Here we show how ultrafast mirror-symmetric photomechanical contractions in the frontal forward-facing left and right eye photo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::294bab9a137f91ec28360f13e30ccc6b
https://doi.org/10.1101/2021.05.03.442473
https://doi.org/10.1101/2021.05.03.442473
Autor:
Craig Montell, Weidi Chen, Mingjie Zhang, Ziling Sun, Fei Ye, Sabrina Asteriti, Wei Liu, Jun Wan, Roger C. Hardie, Zijing Chen, Zeyu Shen
Drosophila TRP is a calcium-permeable cation channel essential for fly visual signal transduction. During phototransduction, Ca2+ mediates both positive and negative feedback regulation on TRP channel activity, possibly via binding to calmodulin (CaM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfe902897861fe824a8f50b4eece834
https://www.repository.cam.ac.uk/handle/1810/315747
https://www.repository.cam.ac.uk/handle/1810/315747
Autor:
Che-Hsiung Liu, Junjie Luo, Zijing Chen, Megan K Oliva, Roger C. Hardie, Simon Collier, Craig Montell
Publikováno v:
J Neurosci
Phototransduction inDrosophilais mediated by phospholipase C (PLC) and Ca2+-permeable TRP channels, but the function of endoplasmic reticulum (ER) Ca2+stores in this important model for Ca2+signaling remains obscure. We therefore expressed a low affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff471fd91439ae3f371768077ca4d66
https://europepmc.org/articles/PMC7159893/
https://europepmc.org/articles/PMC7159893/
SummaryThe daily changes of light and dark exemplify a prominent cue for the synchronization of internal circadian clocks to external time. The match between external and internal time is crucial for the fitness of organisms and desynchronization has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5dd6760c209bd59a8a1ebf909fada3
https://doi.org/10.1101/2020.03.10.985044
https://doi.org/10.1101/2020.03.10.985044