Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Roger A. Klein"'
Autor:
George M. Turco, Ajay Gupta, Philip Monteleone, Kara M. Kelly, Roger D. Klein, Laura Wiltsie, Matthew Barth
Publikováno v:
Pediatric Blood & Cancer. 70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baf642ba6a83be59167bee9508f05bb9
https://doi.org/10.1002/pbc.30324
https://doi.org/10.1002/pbc.30324
Autor:
Roger D. Klein, Qin Shu, Zachary T. Cusumano, Kanna Nagamatsu, Nathaniel C. Gualberto, Aaron J. L. Lynch, Chao Wu, Wenjie Wang, Neha Jain, Jerome S. Pinkner, Gaya K. Amarasinghe, Scott J. Hultgren, Carl Frieden, Matthew R. Chapman
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Curli amyloid fibers are produced as part of the extracellular biofilm matrix and are composed primarily of the major structural subunit CsgA. The CsgE chaperone facilitates the secretion of CsgA through CsgG by forming a cap at the base of
Externí odkaz:
https://doaj.org/article/ff37b00ca12f43a9a3727996214c28c6
Autor:
Roger D. Klein
Publikováno v:
JCO Oncology Practice. 17:647-650
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a143f8d34caf4cb9c1b49db23dcd778f
https://doi.org/10.1200/op.21.00310
https://doi.org/10.1200/op.21.00310
Autor:
Roger D. Klein, Scott J. Hultgren
Publikováno v:
Nat Rev Microbiol
Urinary tract infections (UTIs) are common, recurrent infections that can be mild to life-threatening. The continued emergence of antibiotic resistance, together with our increasing understanding of the detrimental effects conferred by broad-spectrum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a015b4e1e4221ca2fcd8119a67a1458
https://doi.org/10.1038/s41579-020-0324-0
https://doi.org/10.1038/s41579-020-0324-0
Autor:
Roger D. Klein
Publikováno v:
Clinical Chemistry. 66:61-67
BACKGROUND Molecular genetic testing has raised a variety of policy issues, ranging from privacy to reimbursement. Recently, payment policies have become of paramount importance as Medicare implemented the first significant change to test pricing sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a849d53cbbd993d4b9a6ec265e872b
https://doi.org/10.1373/clinchem.2019.308775
https://doi.org/10.1373/clinchem.2019.308775
Autor:
Sarabjot Pabla, Robert J. Seager, Mary Nesline, Paul DePietro, Erik Van Roey, Shuang Gao, Shakti Ramkissoon, Lei Deng, Shengle Zhang, Roger David Klein, Jeffrey M. Conroy
Publikováno v:
Journal of Clinical Oncology. 40:2623-2623
2623 Background: Immune checkpoint inhibitors (ICIs) have emerged as effective treatments in non-small cell lung cancer (NSCLC). While the clinical utility of single agent ICI or in combination with chemotherapy has been well established, there remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::260bc4a948f61a48c4d9a40996590575
https://doi.org/10.1200/jco.2022.40.16_suppl.2623
https://doi.org/10.1200/jco.2022.40.16_suppl.2623
Autor:
Mary Nesline, Sarabjot Pabla, Yong Hee Lee, Paul DePietro, Shengle Zhang, Roger David Klein, Jeffrey M. Conroy, Shakti Ramkissoon, Amy P. Early, Lei Deng, Grace K. Dy
Publikováno v:
Journal of Clinical Oncology. 40:e21167-e21167
e21167 Background: CGIP analyzes FFPE tumor tissue by DNA/RNA sequencing for SNVs, indels, copy gain/loss, fusions, splice variants, MSI and TMB, along with PD-L1 IHC. A purported advantage of CGIP in NSCLC is the ability to identify targeted and imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ea961b29d17a3ac6f06a4448ba01515
https://doi.org/10.1200/jco.2022.40.16_suppl.e21167
https://doi.org/10.1200/jco.2022.40.16_suppl.e21167
Autor:
Robin Gasiorowski, Miriam K. Forbes, Gabriel Silver, Yordanka Krastev, Brenton Hamdorf, Barry Lewis, Michael Tisbury, Merrole Cole-Sinclair, Bruce P. Lanphear, Roger A. Klein, Nigel Holmes, Mark Patrick Taylor
Publikováno v:
JAMA Network Open. 5:e226257
Elevated levels of blood perfluoroalkyl and polyfluoroalkyl substances (PFASs) have been associated with a range of adverse health outcomes. Firefighters have been exposed to PFASs in firefighting foams and have previously been shown to have higher P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5d4dca5272279383036a74beb0c46f
https://doi.org/10.1001/jamanetworkopen.2022.6257
https://doi.org/10.1001/jamanetworkopen.2022.6257
Autor:
James W. Janetka, Scott J. Hultgren, Amarendar Reddy Maddirala, Vasilios Kalas, Jerome S. Pinkner, Roger D. Klein
Publikováno v:
Journal of Medicinal Chemistry. 62:467-479
The F9/Yde/Fml pilus, tipped with the FmlH adhesin, has been shown to provide uropathogenic Escherichia coli (UPEC) a fitness advantage in urinary tract infections (UTIs). Here, we used X-ray structure guided design to optimize our previously describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da688e4ea0bd677cbe8eea4549d44c66
https://doi.org/10.1021/acs.jmedchem.8b01561
https://doi.org/10.1021/acs.jmedchem.8b01561
Autor:
Roger D. Klein, Scott J. Hultgren, James W. Janetka, Henry L. Schreiber, Caitlin N. Spaulding
Publikováno v:
npj Biofilms and Microbiomes, Vol 4, Iss 1, Pp 1-7 (2018)
NPJ Biofilms and Microbiomes
NPJ Biofilms and Microbiomes
The emergence of drug-resistant pathogens has led to a decline in the efficacy of traditional antimicrobial therapy. The rise in resistance has been driven by widespread use, and in some cases misuse, of antibacterial agents in treating a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8479a85653eb53f1aad6ac575eac55ce
http://link.springer.com/article/10.1038/s41522-018-0048-3
http://link.springer.com/article/10.1038/s41522-018-0048-3