Zobrazeno 1 - 10
of 248
pro vyhledávání: '"Roger A Dixon"'
Autor:
Roger A Dixon, Correne A DeCarlo, Stuart W.S. MacDonald, David eVergote, Jack eJhamandas, David eWestaway
Publikováno v:
Frontiers in Aging Neuroscience, Vol 6 (2014)
Objective: Research has reported associations among selected genetic susceptibility biomarkers and risk of (a) normal cognitive aging decrements, (b) established mild cognitive impairment (MCI), and (c) sporadic Alzheimer’s disease (AD). In focusin
Externí odkaz:
https://doaj.org/article/22ec0f31b10e480a9185a69875d064db
Publikováno v:
Frontiers in Psychology, Vol 5 (2014)
Despite ample support for enhanced affective well-being and emotional stability in healthy aging, the role of potentially important dimensions, such as the emotional arousal, has not been systematically investigated in neuroimaging studies. In additi
Externí odkaz:
https://doaj.org/article/2b7347a87aed483697a632c09c408d30
Autor:
Linzy Bohn, Shannon M. Drouin, G. Peggy McFall, Darryl B. Rolfson, Melissa K. Andrew, Roger A. Dixon
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Frailty indicators can operate in dynamic amalgamations of disease conditions, clinical symptoms, biomarkers, medical signals, cognitive characteristics, and even health beliefs and practices. This study is the first to evaluate w
Externí odkaz:
https://doaj.org/article/fe0d9a2ae7bf4d159f8911aff0474e3b
Autor:
Lidan Zheng, Ranmalee Eramudugolla, Nicolas Cherbuin, Shannon M. Drouin, Roger A. Dixon, Kaarin J. Anstey
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Although APOE ɛ4 has been identified as the strongest genetic risk factor for Alzheimer’s Disease, there are some APOE ɛ4 carriers who do not go on to develop Alzheimer’s disease or cognitive impairment. This study aims to investigate
Externí odkaz:
https://doaj.org/article/26f3cd784f384dd2a96e54fe1a354ea6
Autor:
G. Peggy McFall, Linzy Bohn, Myrlene Gee, Shannon M. Drouin, Harrison Fah, Wei Han, Liang Li, Richard Camicioli, Roger A. Dixon
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundPersons with Parkinson’s disease (PD) differentially progress to cognitive impairment and dementia. With a 3-year longitudinal sample of initially non-demented PD patients measured on multiple dementia risk factors, we demonstrate that ma
Externí odkaz:
https://doaj.org/article/cb57e9deb24a42a8a198cfbbbdfcdd56
Autor:
Bryan M. Wong, Christopher Hudson, Emily Snook, Faryan Tayyari, Hyejung Jung, Malcolm A. Binns, Saba Samet, Richard W. Cheng, Carmen Balian, Efrem D. Mandelcorn, Edward Margolin, Elizabeth Finger, Sandra E. Black, David F. Tang-Wai, Lorne Zinman, Brian Tan, Wendy Lou, Mario Masellis, Agessandro Abrahao, Andrew Frank, Derek Beaton, Kelly M. Sunderland, Stephen R. Arnott, ONDRI Investigators, Maria Carmela Tartaglia, Wendy V. Hatch, Sabrina Adamo, Stephen Arnott, Rob Bartha, Courtney Berezuk, Alanna Black, Alisia Bonnick, David Breen, Don Brien, Susan Bronskill, Dennis Bulman, Leanne Casaubon, Ying Chen, Marvin Chum, Brian Coe, Ben Cornish, Jane Lawrence Dewar, Roger A. Dixon, Sherif El-Defrawy, Sali M.K. Farhan, Frederico Faria, Julia Fraser, Mahdi Ghani, Barry Greenberg, Hassan Haddad, Wendy Hatch, Melissa Holmes, Chris Hudson, Peter Kleinstiver, Donna Kwan, Elena Leontieva, Brian Levine, Ed Margolin, Connie Marras, Bill McIlroy, Paula McLaughlin, Manuel Montero Odasso, Doug Munoz, David Munoz, Nuwan Nanayakkara, JB Orange, Miracle Ozzoude, Alicia Peltsch, Pradeep Raamana, Joel Ramirez, Natalie Rashkovan, Angela Roberts, Yanina Sarquis Adamson, Christopher Scott, Michael Strong, Stephen Strothers, Sujeevini Sujanthan, Sean Symons, Athena Theyers, Angela Troyer, Abiramy Uthirakumaran, Karen Van Ooteghem, John Woulfe, Mojdeh Zamyadi, Guangyong (GY) Zou
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
PurposeTauopathy and transactive response DNA binding protein 43 (TDP-43) proteinopathy are associated with neurodegenerative diseases. These proteinopathies are difficult to detect in vivo. This study examined if spectral-domain optical coherence to
Externí odkaz:
https://doaj.org/article/e87ee494733c4014a43bb34084c5fb7d
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2019)
Abstract Background Age-related frailty reflects cumulative multisystem physiological and health decline. Frailty increases the risk of adverse brain and cognitive outcomes, including differential decline and dementia. In a longitudinal sample of non
Externí odkaz:
https://doaj.org/article/3be9b5480919490ead0dd6723f83ae9d
Autor:
Linzy Bohn, G. Peggy McFall, Myrlene Gee, Ronald B. Postuma, Roger A. Dixon, Richard Camicioli
Publikováno v:
Canadian Geriatrics Journal. 26:176-186
Background Parkinson’s disease (PD) increases risk for dementia and cascading adverse outcomes. The eight-item Montreal Parkinson Risk of Dementia Scale (MoPaRDS) is a rapid, in-office dementia screening tool. We examine predictive validity and oth
Autor:
Mackenzie Heal, G. Peggy McFall, David Vergote, Jack H. Jhamandas, David Westaway, Roger A. Dixon
Publikováno v:
Journal of Alzheimer's Disease. 89:265-281
Background: A promising risk loci for sporadic Alzheimer’s disease (AD), Bridging Integrator 1 (BIN1), is thought to operate through the tau pathology pathway. Objective: We examine BIN1 risk for a moderating role with vascular health (pulse pressu
Publikováno v:
Neuropsychology
OBJECTIVE Subjective memory decline (SMD) has been identified as a potential early marker of nonnormal and accelerated cognitive decline. We performed data-driven analyses that integrated trajectory classification with prediction modeling to test dec