Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Roger, Tavendale"'
Autor:
Cyrielle Maroteau, Antonio Espuela-Ortiz, Esther Herrera-Luis, Sundararajan Srinivasan, Fiona Carr, Roger Tavendale, Karen Wilson, Natalia Hernandez-Pacheco, James D Chalmers, Steve Turner, Somnath Mukhopadhyay, Anke-Hilse Maitland-van der Zee, Esteban G Burchard, Maria Pino-Yanes, Simon Young, Glenda Lassi, Adam Platt, Colin N A Palmer, PiCA Consortium
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257396 (2021)
Leukotrienes play a central pathophysiological role in both paediatric and adult asthma. However, 35% to 78% of asthmatics do not respond to leukotriene inhibitors. In this study we tested the role of the LTA4H regulatory variant rs2660845 and age of
Externí odkaz:
https://doaj.org/article/336ae4e495164e158dd79d9dc9b0ed2d
Autor:
Tom Ruffles, Kaninika Basu, Sarah K. Inglis, Stephen Bremner, Heike Rabe, Anjum Memon, Paul Seddon, Roger Tavendale, Colin N. A. Palmer, Somnath Mukhopadhyay, Katy Fidler
Background\ud Mannose binding lectin (MBL) is an important component of the innate immune system. Polymorphisms in the MBL2 gene and promoter region are directly associated with MBL-deficiency. We sought to determine the association between MBL genot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a765c5a78ad9a016a14f5bcf93ae9a
Autor:
Mario Gorenjak, Vojko Berce, Maximilian Schieck, Martin Kerick, Steve Turner, Munir Pirmohamed, Leila Karimi, Almudena Corrales, Staša Jurgec, Marialbert Acosta-Herrera, Katia M.C. Verhamme, Carlos Flores, Natalia Hernandez-Pacheco, Susanne J. H. Vijverberg, Roger Tavendale, Michael Kabesch, Colin N. A. Palmer, Lesly-Anne Samedy-Bates, Jesús Villar, Somnath Mukhopadhyay, Andrea L. Jorgensen, Esteban G. Burchard, Daniel B Hawcutt, Anke H. Maitland-van der Zee, Uroš Potočnik, Maria Pino-Yanes
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
ALLERGY
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Allergy: European Journal of Allergy and Clinical Immunology, 76(4), 1238-1243. Wiley-Blackwell
Allergy
Allergy: European Journal of Allergy and Clinical Immunology, 76(4), 1238-1243. Wiley-Blackwell Publishing Ltd
instname
ALLERGY
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Allergy: European Journal of Allergy and Clinical Immunology, 76(4), 1238-1243. Wiley-Blackwell
Allergy
Allergy: European Journal of Allergy and Clinical Immunology, 76(4), 1238-1243. Wiley-Blackwell Publishing Ltd
Autor:
Glenda Lassi, Maria Pino-Yanes, Somnath Mukhopadhyay, Roger Tavendale, Antonio Espuela-Ortiz, Karen Wilson, Natalia Hernandez-Pacheco, Colin N. A. Palmer, Simon Young, Steve Turner, Adam Platt, Cyrielle Maroteau, Fiona Carr, Esteban G. Burchard, Anke-Hilse Maitland-van der Zee, Esther Herrera-Luis, James D. Chalmers, Sundararajan Srinivasan
Publikováno v:
PLoS ONE, 16(9 September):e0257396. Public Library of Science
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257396 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257396 (2021)
Leukotrienes play a central pathophysiological role in both paediatric and adult asthma. However, 35% to 78% of asthmatics do not respond to leukotriene inhibitors. In this study we tested the role of theLTA4Hregulatory variant rs2660845 and age of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e583b11172691656d2a829454145a0c7
http://sro.sussex.ac.uk/id/eprint/101847/5/journal.pone.0257396.pdf
http://sro.sussex.ac.uk/id/eprint/101847/5/journal.pone.0257396.pdf
Autor:
Roger Tavendale, Daniel B Hawcutt, Anke H. Maitland-van der Zee, Maximilian Schieck, Colin N. A. Palmer, Andrea L. Jorgensen, Uroš Potočnik, Carlos Flores, Maria Pino-Yanes, Susanne J. H. Vijverberg, Somnath Mukhopadhyay, Leila Karimi, Jiang Li, Katia M.C. Verhamme, Michael Kabesch, Natalia Hernandez-Pacheco, Mario Gorenjak, Vojko Berce, Kelan G. Tantisira, Katja Repnik, Steve Turner, Lesly Anne Samedy-Bates, Munir Pirmohamed, Esteban G. Burchard, Jesús Villar
Publikováno v:
Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 11, Iss 733, p 733 (2021)
Volume 11
Issue 8
Journal of Personalized Medicine, 11(8):733. MDPI Multidisciplinary Digital Publishing Institute
Journal of Personalized Medicine, 11(8):733. Multidisciplinary Digital Publishing Institute (MDPI)
Journal of Personalized Medicine, Vol 11, Iss 733, p 733 (2021)
Volume 11
Issue 8
Journal of Personalized Medicine, 11(8):733. MDPI Multidisciplinary Digital Publishing Institute
Journal of Personalized Medicine, 11(8):733. Multidisciplinary Digital Publishing Institute (MDPI)
Inhaled corticosteroids (ICS) are the most common asthma controller medication. An important contribution of genetic factors in ICS response has been evidenced. Here, we aimed to identify novel genetic markers involved in ICS response in asthma. A ge
Autor:
Natalia, Hernandez-Pacheco, Mario, Gorenjak, Jiang, Li, Katja, Repnik, Susanne J, Vijverberg, Vojko, Berce, Andrea, Jorgensen, Leila, Karimi, Maximilian, Schieck, Lesly-Anne, Samedy-Bates, Roger, Tavendale, Jesús, Villar, Somnath, Mukhopadhyay, Munir, Pirmohamed, Katia M C, Verhamme, Michael, Kabesch, Daniel B, Hawcutt, Steve, Turner, Colin N, Palmer, Kelan G, Tantisira, Esteban G, Burchard, Anke H, Maitland-van der Zee, Carlos, Flores, Uroš, Potočnik, Maria, Pino-Yanes
Publikováno v:
Journal of Personalized Medicine
Inhaled corticosteroids (ICS) are the most common asthma controller medication. An important contribution of genetic factors in ICS response has been evidenced. Here, we aimed to identify novel genetic markers involved in ICS response in asthma. A ge
Autor:
Anke M. Hövels, Roger Tavendale, Colin N. A. Palmer, Stephen Bremner, Patrícia Soares, Christina J Jones, Jessie Felton, Katy Fidler, Somnath Mukhopadhyay
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES. 51(8)
The Fc Fragment of IgE Receptor II (FCER2) is expressed in several cells, such as macrophages, eosinophils, B cells and platelets. Studies have suggested that FCER2 is involved in the regulation of IgE responses, growth and differentiation of T and B
Autor:
Katja Repnik, Maximilian Schieck, Steve Turner, Natalia Hernandez-Pacheco, Patrícia Soares, Michael Kabesch, Fook Tim Chew, Esteban G. Burchard, Inger Kull, Erik Melén, Munir Pirmohamed, Vojko Berce, Somnath Mukhopadhyay, Almudena Corrales, Olaia Sardón, Cyrielle Maroteau, Daniel B Hawcutt, Niloufar Farzan, Esther Herrera-Luis, Leila Karimi, Mario Gorenjak, Uroš Potočnik, Yang Yie Sio, Kelan G. Tantisira, Maria Pino-Yanes, Javier Perez-Garcia, Carlos Flores, Raquel Granell, Katia M.C. Verhamme, Susanne J. H. Vijverberg, Jiang Li, Lina Pérez-Méndez, Celeste Eng, Anke H. Maitland-van der Zee, Roger Tavendale, Colin N. A. Palmer, Ryan Lethem
Publikováno v:
European respiratory journal, 57(5):2003388. European Respiratory Society
Eur Respir J
Hernandez-Pacheco, N, Granell, R & Maitland-van der Zee, A 2021, ' Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use ', European Respiratory Journal, vol. 57, no. 5, 2003388 . https://doi.org/10.1183/13993003.03388-2020
EUROPEAN RESPIRATORY JOURNAL
European Respiratory Journal, 57(5):2003388. European Respiratory Society
Eur Respir J
Hernandez-Pacheco, N, Granell, R & Maitland-van der Zee, A 2021, ' Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use ', European Respiratory Journal, vol. 57, no. 5, 2003388 . https://doi.org/10.1183/13993003.03388-2020
EUROPEAN RESPIRATORY JOURNAL
European Respiratory Journal, 57(5):2003388. European Respiratory Society
RationaleSubstantial variability in response to asthma treatment with inhaled corticosteroids (ICS) has been described among individuals and populations, suggesting the contribution of genetic factors. Nonetheless, only a few genes have been identifi
Autor:
Somnath Mukhopadhyay, James D. Chalmers, Anke-Hilse Maitland-van der Zee, Maria Pino-Yanes, Karen Wilson, Esther Herrera-Luis, Roger Tavendale, Natalia Hernandez-Pacheco, Glenda Lassi, Colin N. A. Palmer, Adam Platt, Sundararajan Srinivasan, Simon Young, Esteban G. Burchard, Steve Turner, Cyrielle Maroteau, Fiona Carr, Antonio Espuela-Ortiz
Leukotrienes play a central pathophysiological role in both pediatric and adult asthma. However, 35% to 78% of asthmatics do not respond to leukotriene inhibitors. To test the role of theLTA4Hregulatory variant rs2660845 and age of asthma onset in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::badf49c70efe06ffdd9e00ee0562eb93
https://doi.org/10.1101/2020.10.05.20206847
https://doi.org/10.1101/2020.10.05.20206847
Autor:
Jonathan Grigg, Roger Tavendale, Helen Smith, Somnath Mukhopadhyay, Roberta Littleford, Kristina Pilvinyte, Colin N. A. Palmer, Fiona Hogarth, Christina J Jones, Steve Turner, Thomas Ruffles, Brian J. Lipworth, Petra Rauchhaus
Publikováno v:
Paediatric asthma and allergy.
Introduction: The A allele of rs1042713 (Arg16 amino acid) is associated with poor response to long-acting β2 agonist (LABA) in young people with asthma. We aimed to evaluate whether prescribing asthma controller medication according to rs1042713 ge