Zobrazeno 1 - 10
of 563
pro vyhledávání: '"Roger, Stupp"'
Autor:
Víctor A. Arrieta, Andrew Gould, Kwang-Soo Kim, Karl J. Habashy, Crismita Dmello, Gustavo I. Vázquez-Cervantes, Irina Palacín-Aliana, Graysen McManus, Christina Amidei, Cristal Gomez, Silpol Dhiantravan, Li Chen, Daniel Y. Zhang, Ruth Saganty, Meghan E. Cholak, Surya Pandey, Matthew McCord, Kathleen McCortney, Brandyn Castro, Rachel Ward, Miguel Muzzio, Guillaume Bouchoux, Carole Desseaux, Michael Canney, Alexandre Carpentier, Bin Zhang, Jason M. Miska, Maciej S. Lesniak, Craig M. Horbinski, Rimas V. Lukas, Roger Stupp, Catalina Lee-Chang, Adam M. Sonabend
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Given the marginal penetration of most drugs across the blood-brain barrier, the efficacy of various agents remains limited for glioblastoma (GBM). Here we employ low-intensity pulsed ultrasound (LIPU) and intravenously administered microbub
Externí odkaz:
https://doaj.org/article/79679c002d644430b29884550815aa26
Autor:
Priya Kumthekar, Madison Lyleroehr, Leilani Lacson, Rimas V. Lukas, Karan Dixit, Roger Stupp, Timothy Kruser, Jeff Raizer, Alexander Hou, Sean Sachdev, Margaret Schwartz, Jessica Bajas PA, Ray Lezon, Karyn Schmidt, Christina Amidei, Karen Kaiser
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Tumor Treating Fields (TTFields) Therapy is an FDA-approved therapy in the first line and recurrent setting for glioblastoma. Despite Phase 3 evidence showing improved survival with TTFields, it is not uniformly utilized. We aimed
Externí odkaz:
https://doaj.org/article/d7895edb0e734564b205c572113db00c
Autor:
Alexandre Carpentier, Roger Stupp, Adam M. Sonabend, Henry Dufour, Olivier Chinot, Bertrand Mathon, François Ducray, Jacques Guyotat, Nathalie Baize, Philippe Menei, John de Groot, Jeffrey S. Weinberg, Benjamin P. Liu, Eric Guemas, Carole Desseaux, Charlotte Schmitt, Guillaume Bouchoux, Michael Canney, Ahmed Idbaih
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Here, the results of a phase 1/2 single-arm trial (NCT03744026) assessing the safety and efficacy of blood-brain barrier (BBB) disruption with an implantable ultrasound system in recurrent glioblastoma patients receiving carboplatin are repo
Externí odkaz:
https://doaj.org/article/e712a20f4c934b6c8309df6f0e891005
Autor:
Matthew McCord, Pouya Jamshidi, Vineeth Thirunavu, Lucas Santana-Santos, Erica Vormittag-Nocito, David Dittman, Stephanie Parker, Joseph Baczkowski, Lawrence Jennings, Jordain Walshon, Kathleen McCortney, Kristyn Galbraith, Hui Zhang, Rimas V. Lukas, Roger Stupp, Karan Dixit, Priya Kumthekar, Amy B. Heimberger, Matija Snuderl, Craig Horbinski
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract MGMT promoter methylation testing is required for prognosis and predicting temozolomide response in gliomas. Accurate results depend on sufficient tumor cellularity, but histologic estimates of cellularity are subjective. We sought to determ
Externí odkaz:
https://doaj.org/article/c76fde180aa142ce9de66226ad2f660b
Autor:
Pierre Bady, Christine Marosi, Michael Weller, Bjørn H. Grønberg, Henrik Schultz, Martin J. B. Taphoorn, Johanna M. M. Gijtenbeek, Martin J. van den Bent, Andreas von Deimling, Roger Stupp, Annika Malmström, Monika E. Hegi
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-18 (2022)
Abstract Elderly patients represent a growing proportion of individuals with glioblastoma, who however, are often excluded from clinical trials owing to poor expected prognosis. We aimed at identifying age-related molecular differences that would jus
Externí odkaz:
https://doaj.org/article/f25d671f678e412283b2b0a390e01828
Autor:
Víctor A. Arrieta, Crismita Dmello, Daniel J. McGrail, Daniel J. Brat, Catalina Lee-Chang, Amy B. Heimberger, Dhan Chand, Roger Stupp, Adam M. Sonabend
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
Immune checkpoint blockade (ICB) has revolutionized modern cancer therapy, arousing great interest in the neuro-oncology community. While several reports show that subsets of patients with glioma exhibit durable responses to immunotherapy, the effica
Externí odkaz:
https://doaj.org/article/e5116efe28b640fab150259dd932a2e9
Autor:
Tobias Kessler, Anne Berberich, Ahmed Sadik, Felix Sahm, Thierry Gorlia, Christoph Meisner, Dirk C. Hoffmann, Antje Wick, Philipp Kickingereder, Petra Rübmann, Martin Bendszus, Christiane Opitz, Michael Weller, Martin van denBent, Roger Stupp, Frank Winkler, Alba Brandes, Andreas vonDeimling, Michael Platten, Wolfgang Wick
Publikováno v:
Cancer Medicine, Vol 9, Iss 22, Pp 8373-8385 (2020)
Abstract Background Gliomas evade current therapies through primary and acquired resistance and the effect of temozolomide is mainly restricted to methylguanin‐O6-methyltransferase promoter (MGMT) promoter hypermethylated tumors. Further resistance
Externí odkaz:
https://doaj.org/article/c172af256fd74be38c24abc7248654c9
Autor:
Claudia Canella, Michael Mikolasek, Matthias Rostock, Matthias Guckenberger, Josef Jenewein, Esther Linka, Claudia Six, Sarah Stoll, Roger Stupp, Claudia M. Witt
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Although cancer-related fatigue (CRF) has gained increased attention in the past decade, therapy remains a challenge. Treatment programs are more likely to be effective if the needs and interests of the persons involved are well r
Externí odkaz:
https://doaj.org/article/28f9b9e2afa54271a19b080f6c12303d
Autor:
Chandrakanth Jayachandran Preetha, MSc, Hagen Meredig, MD, Gianluca Brugnara, MD, Mustafa A Mahmutoglu, MD, Martha Foltyn, MD, Fabian Isensee, PhD, Tobias Kessler, MD, Irada Pflüger, MD, Marianne Schell, MD, Ulf Neuberger, MD, Jens Petersen, PhD, Antje Wick, MD, Sabine Heiland, ProfPhD, Jürgen Debus, ProfMD, Michael Platten, ProfMD, Ahmed Idbaih, MD, Alba A Brandes, ProfMD, Frank Winkler, ProfMD, Martin J van den Bent, ProfMD, Burt Nabors, ProfMD, Roger Stupp, ProfMD, Klaus H Maier-Hein, ProfPhD, Thierry Gorlia, PhD, Jörg-Christian Tonn, ProfMD, Michael Weller, ProfMD, Wolfgang Wick, ProfMD, Martin Bendszus, ProfMD, Philipp Vollmuth, MD
Publikováno v:
The Lancet: Digital Health, Vol 3, Iss 12, Pp e784-e794 (2021)
Summary: Background: Gadolinium-based contrast agents (GBCAs) are widely used to enhance tissue contrast during MRI scans and play a crucial role in the management of patients with cancer. However, studies have shown gadolinium deposition in the brai
Externí odkaz:
https://doaj.org/article/1d0604c10cd74d3aaeb41f01be7c60b0
Autor:
Andrew Gould, Victor Andrés Arrieta Gonzales, Crismita Clement Dmello, Ruth Saganty, Rimas V. Lukas, Daniel Y. Zhang, Amy B. Heimberger, Michael Canney, Alexandre Carpentier, Carole Desseaux, Guillaume Bouchoux, Roger Stupp, Adam M. Sonabend
Publikováno v:
Advances in Oncology. 3:77-86
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7764978c1ecb4b8c7a11155921c6f847
https://doi.org/10.1016/j.yao.2023.01.017
https://doi.org/10.1016/j.yao.2023.01.017