Zobrazeno 1 - 10
of 395
pro vyhledávání: '"Roger, Le Grand"'
Autor:
Joshua S. Woodworth, Vanessa Contreras, Dennis Christensen, Thibaut Naninck, Nidhal Kahlaoui, Anne-Sophie Gallouët, Sébastien Langlois, Emma Burban, Candie Joly, Wesley Gros, Nathalie Dereuddre-Bosquet, Julie Morin, Ming Liu Olsen, Ida Rosenkrands, Ann-Kathrin Stein, Grith Krøyer Wood, Frank Follmann, Thomas Lindenstrøm, Tu Hu, Roger Le Grand, Gabriel Kristian Pedersen, Rasmus Mortensen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Development of new vaccines tailored for difficult-to-target diseases is hampered by a lack of diverse adjuvants for human use, and none of the currently available adjuvants induce Th17 cells. Here, we develop a liposomal adjuvant, CAF®10b,
Externí odkaz:
https://doaj.org/article/247707a325064a6ea6e1237d4d196721
Autor:
Steve Huvelle, Antoine Pinon, Christine Coulon, Thomas Bonasera, Catherine Chapon, Thibaut Naninck, Roger Le Grand, Chris M. Parry, Bertrand Kuhnast, Fabien Caillé
Publikováno v:
ACS Omega, Vol 9, Iss 40, Pp 41732-41741 (2024)
Externí odkaz:
https://doaj.org/article/19496fc1ee754918bc9b9e3a2670b273
Autor:
Louis Reot, Cindy Adapen, Claude Cannou, Natalia Nunez, Sabrine Lakoum, Camille Pimienta, Laetitia Lacroix, Olivier Binois, Nelly Frydman, Marie-Thérèse Nugeyre, Roger Le Grand, Elisabeth Menu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Seminal plasma (SP) is the main vector of C. trachomatis (CT) during heterosexual transmission from male to female. It has immunomodulatory properties and impacts the susceptibility to HIV-1 infection, but its role has not been explored duri
Externí odkaz:
https://doaj.org/article/51fd9c8595f84ffe97cf084718c8c1cc
Autor:
Charles Egloff, Claire-Maëlle Fovet, Jessica Denis, Quentin Pascal, Laetitia Bossevot, Sophie Luccantoni, Marco Leonec, Nathalie Dereuddre-Bosquet, Isabelle Leparc-Goffart, Roger Le Grand, Guillaume André Durand, Cyril Badaut, Olivier Picone, Pierre Roques
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Early pregnancy Zika virus (ZIKV) infection is associated with major brain damage in fetuses, leading to microcephaly in 0.6–5.0% of cases, but the underlying mechanisms remain largely unknown. Methods To understand the kinetics
Externí odkaz:
https://doaj.org/article/9e485b9b11a64d92b877266a8cf4b633
Autor:
Katia Lemdani, Romain Marlin, Céline Mayet, Vladimir Perkov, Quentin Pascal, Manon Ripoll, Francis Relouzat, Nina Dhooge, Laetitia Bossevot, Nathalie Dereuddre-Bosquet, Gihad Dargazanli, Kevin Thibaut-Duprey, Jean Haensler, Catherine Chapon, Christine Prost, Roger Le Grand
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract The characterization of vaccine distribution to relevant tissues after in vivo administration is critical to understanding their mechanisms of action. Vaccines based on mRNA lipid nanoparticles (LNPs) are now being widely considered against
Externí odkaz:
https://doaj.org/article/9a16683cef5943cfbca28efe52bdabf2
Autor:
Mathilde Galhaut, Urban Lundberg, Romain Marlin, Robert Schlegl, Stefan Seidel, Ursula Bartuschka, Jürgen Heindl-Wruss, Francis Relouzat, Sébastien Langlois, Nathalie Dereuddre-Bosquet, Julie Morin, Maxence Galpin-Lebreau, Anne-Sophie Gallouët, Wesley Gros, Thibaut Naninck, Quentin Pascal, Catherine Chapon, Karine Mouchain, Guillaume Fichet, Julien Lemaitre, Mariangela Cavarelli, Vanessa Contreras, Nicolas Legrand, Andreas Meinke, Roger Le Grand
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background The fight against COVID-19 requires mass vaccination strategies, and vaccines inducing durable cross-protective responses are still needed. Inactivated vaccines have proven lasting efficacy against many pathogens and good safety r
Externí odkaz:
https://doaj.org/article/b20cf0b0a10841d78b8331ab24c32b42
Autor:
Elodie Paulet, Vanessa Contreras, Mathilde Galhaut, Ida Rosenkrands, Martin Holland, Matthew Burton, Jes Dietrich, Anne-Sophie Gallouet, Nathalie Bosquet, Francis Relouzat, Sébastien Langlois, Frank Follmann, Roger Le Grand, Marc Labetoulle, Antoine Rousseau
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 8, p e0012388 (2024)
BackgroundTrachoma is a leading cause of infection-related blindness worldwide. This disease is caused by recurrent Chlamydia trachomatis (Ct) infections of the conjunctiva and develops in two phases: i) active (acute trachoma, characterized by folli
Externí odkaz:
https://doaj.org/article/567abb83692e47a99420ae56ed8462b9
Autor:
Klara Lenart, Rodrigo Arcoverde Cerveira, Fredrika Hellgren, Sebastian Ols, Daniel J. Sheward, Changil Kim, Alberto Cagigi, Matthew Gagne, Brandon Davis, Daritza Germosen, Vicky Roy, Galit Alter, Hélène Letscher, Jérôme Van Wassenhove, Wesley Gros, Anne-Sophie Gallouët, Roger Le Grand, Harry Kleanthous, Mimi Guebre-Xabier, Ben Murrell, Nita Patel, Gregory Glenn, Gale Smith, Karin Loré
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract The immune responses to Novavax’s licensed NVX-CoV2373 nanoparticle Spike protein vaccine against SARS-CoV-2 remain incompletely understood. Here, we show in rhesus macaques that immunization with Matrix-MTM adjuvanted vaccines predominant
Externí odkaz:
https://doaj.org/article/c088a289c59c484090d22680d31eac78
Autor:
Caroline Passaes, Delphine Desjardins, Anaïs Chapel, Valérie Monceaux, Julien Lemaitre, Adeline Mélard, Federico Perdomo-Celis, Cyril Planchais, Maël Gourvès, Nastasia Dimant, Annie David, Nathalie Dereuddre-Bosquet, Aurélie Barrail-Tran, Hélène Gouget, Céline Guillaume, Francis Relouzat, Olivier Lambotte, Jérémie Guedj, Michaela Müller-Trutwin, Hugo Mouquet, Christine Rouzioux, Véronique Avettand-Fenoël, Roger Le Grand, Asier Sáez-Cirión
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract HIV remission can be achieved in some people, called post-treatment HIV controllers, after antiretroviral treatment discontinuation. Treatment initiation close to the time of infection was suggested to favor post-treatment control, but the c
Externí odkaz:
https://doaj.org/article/661b86229b42429d8450453e606a9ab0
Autor:
Paul-Henri Romeo, Laurine Conquet, Sébastien Messiaen, Quentin Pascal, Stéphanie G. Moreno, Anne Bravard, Jacqueline Bernardino-Sgherri, Nathalie Dereuddre-Bosquet, Xavier Montagutelli, Roger Le Grand, Vanessa Petit, Federica Ferri
Publikováno v:
Antioxidants, Vol 13, Iss 9, p 1083 (2024)
Few therapeutic options are available to treat COVID-19. The KEAP1/NRF2 pathway, the major redox-responsive pathway, has emerged as a potential therapeutic target for COVID-19 as it regulates redox homeostasis and inflammation that are altered during
Externí odkaz:
https://doaj.org/article/9045a7db6cb849198cd19ce7364ba5aa