Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Roger, Caothien"'
Autor:
Honglin Chen, Steffen Durinck, Hetal Patel, Oded Foreman, Kathryn Mesh, Jeffrey Eastham, Roger Caothien, Robert J. Newman, Merone Roose-Girma, Spyros Darmanis, Soren Warming, Annalisa Lattanzi, Yuxin Liang, Benjamin Haley
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 431-449 (2022)
With the aim of expediting drug target discovery and validation for respiratory diseases, we developed an optimized method for in situ somatic gene disruption in murine lung epithelial cells via AAV6-mediated CRISPR-Cas9 delivery. Efficient gene edit
Externí odkaz:
https://doaj.org/article/113e78dbbb674feba29efc5e54161173
Autor:
Akshay T. Krishnamurty, Justin A. Shyer, Minh Thai, Vineela Gandham, Matthew B. Buechler, Yeqing Angela Yang, Rachana N. Pradhan, Amber W. Wang, Patricia L. Sanchez, Yan Qu, Beatrice Breart, Cécile Chalouni, Debra Dunlap, James Ziai, Justin Elstrott, Neelie Zacharias, Weiguang Mao, Rebecca K. Rowntree, Jack Sadowsky, Gail D. Lewis, Thomas H. Pillow, Barzin Y. Nabet, Romain Banchereau, Lucinda Tam, Roger Caothien, Natasha Bacarro, Merone Roose-Girma, Zora Modrusan, Sanjeev Mariathasan, Sören Müller, Shannon J. Turley
Publikováno v:
Nature. 611:148-154
Recent single-cell studies of cancer in both mice and humans have identified the emergence of a myofibroblast population specifically marked by the highly restricted leucine-rich-repeat-containing protein 15 (LRRC15)1–3. However, the molecular sign
Autor:
Charles Yu, Roger Caothien, Marques Jackson, Brian Nakao, Anna Pham, Lucinda Tam, Merone Roose-Girma
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629895
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7201a40d22dd298aefa6f9e3ee275123
https://doi.org/10.1007/978-1-0716-2990-1_7
https://doi.org/10.1007/978-1-0716-2990-1_7
Autor:
Charles Yu, Roger Caothien, Anna Pham, Lucinda Tam, Tuija Alcantar, Natasha Bacarro, Juan Reyes, Marques Jackson, Brian Nakao, Merone Roose-Girma
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629895
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::012421f5ae13ec04c436d5c3b95bf2d6
https://doi.org/10.1007/978-1-0716-2990-1_5
https://doi.org/10.1007/978-1-0716-2990-1_5
Autor:
Roger Caothien, Charles Yu, Lucinda Tam, Robert Newman, Brian Nakao, Tuija Alcantar, Natasha Bacarro, Juan Reyes, Anna Pham, Merone Roose-Girma
Publikováno v:
Molecular Biology Reports. 49:3281-3288
Gene targeting in mouse ES cells replaces or modifies genes of interest; conditional alleles, reporter knock-ins, and amino acid changes are common examples of how gene targeting is used. For example, enhanced green fluorescent protein or Cre recombi
Autor:
Yeqing Angela Yang, Christian Cox, Matthew B. Buechler, Zora Modrusan, Merone Roose-Girma, Rachana N. Pradhan, Roger Caothien, Richard Bourgon, Sören Müller, Amber W. Wang, Akshay T. Krishnamurty, Shannon J. Turley, Aslihan Karabacak Calviello, Joseph R. Arron, Lucinda Tam
Publikováno v:
Nature. 593:575-579
Fibroblasts are non-haematopoietic structural cells that define the architecture of organs, support the homeostasis of tissue-resident cells and have key roles in fibrosis, cancer, autoimmunity and wound healing1. Recent studies have described fibrob
Autor:
Roger Caothien, Charles Yu, Lucinda Tam, Robert Newman, Brian Nakao, Tuija Alcantar, Natasha Baccaro, Juan Reyes, Anna Pham, Merone Roose-Girma
Gene targeting in mouse ES cells replaces or modifies genes of interest; conditional alleles, reporter knock-ins, and amino acid changes are common examples of how gene targeting is used. For example, enhanced green fluorescent protein or Cre recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8892dcebaa313d5edd36dd6bcc08399e
https://doi.org/10.21203/rs.3.rs-748320/v1
https://doi.org/10.21203/rs.3.rs-748320/v1
Autor:
Akshay T, Krishnamurty, Justin A, Shyer, Minh, Thai, Vineela, Gandham, Matthew B, Buechler, Yeqing Angela, Yang, Rachana N, Pradhan, Amber W, Wang, Patricia L, Sanchez, Yan, Qu, Beatrice, Breart, Cécile, Chalouni, Debra, Dunlap, James, Ziai, Justin, Elstrott, Neelie, Zacharias, Weiguang, Mao, Rebecca K, Rowntree, Jack, Sadowsky, Gail D, Lewis, Thomas H, Pillow, Barzin Y, Nabet, Romain, Banchereau, Lucinda, Tam, Roger, Caothien, Natasha, Bacarro, Merone, Roose-Girma, Zora, Modrusan, Sanjeev, Mariathasan, Sören, Müller, Shannon J, Turley
Publikováno v:
Nature. 611(7934)
Recent single-cell studies of cancer in both mice and humans have identified the emergence of a myofibroblast population specifically marked by the highly restricted leucine-rich-repeat-containing protein 15 (LRRC15)
Autor:
Alexander D, Gitlin, Klaus, Heger, Alexander F, Schubert, Rohit, Reja, Donghong, Yan, Victoria C, Pham, Eric, Suto, Juan, Zhang, Youngsu C, Kwon, Emily C, Freund, Jing, Kang, Anna, Pham, Roger, Caothien, Natasha, Bacarro, Trent, Hinkle, Min, Xu, Brent S, McKenzie, Benjamin, Haley, Wyne P, Lee, Jennie R, Lill, Merone, Roose-Girma, Monika, Dohse, Joshua D, Webster, Kim, Newton, Vishva M, Dixit
Publikováno v:
Nature. 587(7833)
Mutations in the death receptor FAS
Inflammatory Bowel Disease Susceptibility Gene C1ORF106 Regulates Intestinal Epithelial Permeability
Autor:
Ryan Ichikawa, Roger Caothien, Paolo Manzanillo, Arthur Wuster, Naruhisa Ota, Alexis Scherl, Gabriela Alvarado, Meron Roose-Girma, Youngsu Kwon, Mary E. Keir, Tangsheng Yi, Søren Warming, Brent S. McKenzie, Bingbing Dai, Wenjun Ouyang, Benjamin Haley, Maria Mouchess
Publikováno v:
ImmunoHorizons. 2:164-171
Intestinal epithelial cells form a physical barrier that is tightly regulated to control intestinal permeability. Proinflammatory cytokines, such as TNF-α, increase epithelial permeability through disruption of epithelial junctions. The regulation o