Adherent invasive Escherichia coli (AIEC) strain LF82, but not Candida albicans, plays a profibrogenic role in the intestine

Autor: Dina Chokr, Marjorie Cornu, Christel Neut, Clovis Bortolus, Rogatien Charlet, Pierre Desreumaux, Silvia Speca, Boualem Sendid

Publikováno v: Gut Pathogens, Vol 13, Iss 1, Pp 1-10 (2021)

Abstract Background Intestinal fibrosis is a frequent complication of Crohn’s disease. However, the factors that cause chronicity and promote fibrogenesis are not yet understood. Aims In the present study, we evaluated the profibrotic effects of ad

Externí odkaz: https://doaj.org/article/e6317032f90244d796b013f38488586c

A decrease in anaerobic bacteria promotes Candida glabrata overgrowth while β-glucan treatment restores the gut microbiota and attenuates colitis

Autor: Rogatien Charlet, Clovis Bortolus, Melissandre Barbet, Boualem Sendid, Samir Jawhara

Publikováno v: Gut Pathogens, Vol 10, Iss 1, Pp 1-9 (2018)

Abstract Background The intestinal microbiota plays a crucial role in the maintenance of gut homeostasis. Changes in crosstalk between the intestinal epithelial cells, immune cells and the microbiota are critically involved in the development of infl

Externí odkaz: https://doaj.org/article/4eaef966353d4d0ba141d75d30a4f7f9

Fungal Chitin Reduces Platelet Activation Mediated via TLR8 Stimulation

Autor: Jordan Leroy, Clovis Bortolus, Karine Lecointe, Melissa Parny, Rogatien Charlet, Boualem Sendid, Samir Jawhara

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)

Platelets play an important role in the innate immune response. During candidaemia, circulating fungal polysaccharides, including chitin, are released into the bloodstream and can interact with platelets and induce modulation of platelet activities.

Externí odkaz: https://doaj.org/article/a217cd8f32c649b98f6f1bb9c6fac9e3

Intravenous Immunoglobulin Therapy Eliminates Candida albicans and Maintains Intestinal Homeostasis in a Murine Model of Dextran Sulfate Sodium-Induced Colitis

Autor: Rogatien Charlet, Boualem Sendid, Srini V. Kaveri, Daniel Poulain, Jagadeesh Bayry, Samir Jawhara

Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 6, p 1473 (2019)

Intravenous immunoglobulin (IVIg) therapy has diverse anti-inflammatory and immunomodulatory effects and has been employed successfully in autoimmune and inflammatory diseases. The role of IVIg therapy in the modulation of intestinal inflammation and

Externí odkaz: https://doaj.org/article/6302b5e076804b269f5b8dcec6e2d45b

H89 Treatment Reduces Intestinal Inflammation and Candida albicans Overgrowth in Mice

Autor: Rogatien Charlet, Ali Bettaieb, Samir Jawhara, Corentin Dumortier

Publikováno v: Microorganisms, Vol 8, Iss 2039, p 2039 (2020)
Microorganisms
Microorganisms, MDPI, 2020, 8 (12), pp.2039. ⟨10.3390/microorganisms8122039⟩
Microorganisms, 2020, 8 (12), pp.2039. ⟨10.3390/microorganisms8122039⟩
Volume 8
Issue 12

Deregulation of the dynamic crosstalk between the gut microbiota, intestinal epithelial cells, and immune cells is critically involved in the development of inflammatory bowel disease and the overgrowth of opportunistic pathogens, including the human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea460d232b812eff96ad4ca47191390e
https://www.mdpi.com/2076-2607/8/12/2039