Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Rogério Silva do Nascimento"'
1
Akademický článek
T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections
Autor: Igor Santiago-Carvalho, Gislane Almeida-Santos, Bruna Gois Macedo, Caio Cesar Barbosa-Bomfim, Fabricio Moreira Almeida, Marcos Vinícios Pinheiro Cione, Trupti Vardam-Kaur, Mia Masuda, Sarah Van Dijk, Bruno Marcel Melo, Rogério Silva do Nascimento, Rebeka da Conceição Souza, Alba Lucínia Peixoto-Rangel, Robson Coutinho-Silva, Mario Hiroyuki Hirata, José Carlos Alves-Filho, José Maria Álvarez, Elena Lassounskaia, Henrique Borges da Silva, Maria Regina D’Império-Lima
Publikováno v: Cell Reports, Vol 42, Iss 11, Pp 113448- (2023)
Summary: CD4+ T cells are key components of the immune response during lung infections and can mediate protection against tuberculosis (TB) or influenza. However, CD4+ T cells can also promote lung pathology during these infections, making it unclear
Externí odkaz: https://doaj.org/article/fe5978ef17a34b0d8f92e8f6d5272a3f
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2
Akademický článek
Absence of Bim sensitizes mice to experimental Trypanosoma cruzi infection
Autor: Marcela Hernández-Torres, Rogério Silva do Nascimento, Monica Cardozo Rebouças, Alexandra Cassado, Kely Catarine Matteucci, Maria Regina D’Império-Lima, José Ronnie C. Vasconcelos, Karina R. Bortoluci, José Maria Alvarez, Gustavo P. Amarante-Mendes
Publikováno v: Cell Death and Disease, Vol 12, Iss 7, Pp 1-8 (2021)
Abstract Chagas disease is a life-threatening disorder caused by the protozoan parasite Trypanosoma cruzi. Parasite-specific antibodies, CD8+ T cells, as well as IFN-γ and nitric oxide (NO) are key elements of the adaptive and innate immunity agains
Externí odkaz: https://doaj.org/article/2c6b3786ec0642e3842473ee3f88b295
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4
Akademický článek
MyD88 activation in cardiomyocytes contributes to the heart immune response to acute Trypanosoma cruzi infection with no effect on local parasite control.
Autor: Danni Yohani Santana, Rafael Moysés Salgado, Marina Fevereiro, Rogério Silva do Nascimento, Raissa Fonseca, Niels Olsen Saraiva Câmara, Sabrina Epiphanio, Cláudio Romero Farias Marinho, Maria Luiza Barreto-Chaves, Maria Regina D' Império-Lima, José M Álvarez
Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 8, p e0006617 (2018)
Cardiomyopathy is the most serious consequence of Chagas disease, a neglected human disorder caused by Trypanosoma cruzi infection. Because T. cruzi parasites invade cardiomyocytes, we sought to investigate whether these cells recognize the parasite
Externí odkaz: https://doaj.org/article/6b89d81dc8f84510916bbbb27095f04b
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5
Akademický článek
Programmed Cell Death Protein 1–PDL1 Interaction Prevents Heart Damage in Chronic Trypanosoma cruzi Infection
Autor: Raíssa Fonseca, Rafael Moysés Salgado, Henrique Borges da Silva, Rogério Silva do Nascimento, Maria Regina D’Império-Lima, José Maria Alvarez
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
Chagas disease is a neglected parasitic infection that affects around six to seven million people, mainly in Latin America. About 30–35% of infected people present chronic Chagas cardiomyopathy (CCC), which eventually leads to death. This condition
Externí odkaz: https://doaj.org/article/809f2e7cabd14fb1a8201ed9f8decfae
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6
Akademický článek
The liver plays a major role in clearance and destruction of blood trypomastigotes in Trypanosoma cruzi chronically infected mice.
Autor: Luiz Roberto Sardinha, Tainá Mosca, Rosa Maria Elias, Rogério Silva do Nascimento, Lígia A Gonçalves, Daniella Zanetti Bucci, Cláudio Romero Farias Marinho, Carlos Penha-Gonçalves, Maria Regina D'Império Lima, José Maria Alvarez
Publikováno v: PLoS Neglected Tropical Diseases, Vol 4, Iss 1, p e578 (2010)
Intravenous challenge with Trypanosoma cruzi can be used to investigate the process and consequences of blood parasite clearance in experimental Chagas disease. One hour after intravenous challenge of chronically infected mice with 5x10(6) trypomasti
Externí odkaz: https://doaj.org/article/420c1cbe5d7f445688450321921ad5b6
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8
Harmful Effects of Granulocytic Myeloid-Derived Suppressor Cells on Tuberculosis Caused by Hypervirulent Mycobacteria
Autor: Araceli Aparecida Hastreiter, Mario Hiroyuki Hirata, Fabrício Moreira Almeida, Maria Regina D'Império Lima, Gislane de Almeida Santos, Elena B. Lasunskaia, José M. Alvarez, Érika Machado de Salles, Eduardo P. Amaral, Caio César Barbosa Bomfim, Rogério Silva do Nascimento, Ricardo Ambrósio Fock, Thatiana Lopes Biá Ventura Simão, Andreza Linhares Rezende, Igor Santiago-Carvalho
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
J Infect Dis
Background The role of myeloid-derived suppressor cells (MDSCs) in patients with severe tuberculosis who suffer from uncontrolled pulmonary inflammation caused by hypervirulent mycobacterial infection remains unclear. Methods This issue was addressed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c59e20af5a6fef68980c0d32a0f8c4a
https://doi.org/10.1093/infdis/jiaa708
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10
Murine infection by Trypanossoma cruzi Sylvio X10/4: The humoral response to the parasite in the absence of the CD28 receptor
Autor: Rogério Silva do Nascimento
Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP
A infecção murina pelo T. cruzi Sylvio X10/4, um parasita de baixa virulência, possibilita que camundongos CD28KO infectados sobrevivam por um longo período de tempo. Esta característica permite estudar o impacto da ausência de CD28 sobre vári
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247ef363c655c6c6a45d3d35764cd580
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