Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rogério Amino"'
Autor:
Yara C Blanco, Alessandro S Farias, Uta Goelnitz, Stefanie C P Lopes, Wagner W Arrais-Silva, Bruna O Carvalho, Rogério Amino, Gerhard Wunderlich, Leonilda M B Santos, Selma Giorgio, Fabio T M Costa
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3126 (2008)
BACKGROUND: Cerebral malaria (CM) is a syndrome characterized by neurological signs, seizures and coma. Despite the fact that CM presents similarities with cerebral stroke, few studies have focused on new supportive therapies for the disease. Hyperba
Externí odkaz:
https://doaj.org/article/a8a69cfc675d4dee9922d73c36ff33cd
Autor:
Pauline Formaglio, Marina E. Wosniack, Raphael M. Tromer, Jaderson G. Polli, Yuri B. Matos, Hang Zhong, Ernesto P. Raposo, Marcos G. E. da Luz, Rogerio Amino
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Plasmodium sporozoites actively migrate in the dermis and enter blood vessels to infect the liver. Despite their importance for malaria infection, little is known about these cutaneous processes. We combine intravital imaging in a rodent mal
Externí odkaz:
https://doaj.org/article/cbf177dddd22493795a1a330835f24ec
Autor:
Manuela C. Aguirre-Botero, Lawrence T. Wang, Pauline Formaglio, Eduardo Aliprandini, Jean-Michel Thiberge, Arne Schön, Yevel Flores-Garcia, Shamika Mathis-Torres, Barbara J. Flynn, Lais da Silva Pereira, Yann Le Duff, Mathew Hurley, Adéla Nacer, Paul W. Bowyer, Fidel Zavala, Azza H. Idris, Joseph R. Francica, Robert A. Seder, Rogerio Amino
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112681- (2023)
Summary: Human monoclonal antibodies (hmAbs) targeting the Plasmodium falciparum circumsporozoite protein (PfCSP) on the sporozoite surface are a promising tool for preventing malaria infection. However, their mechanisms of protection remain unclear.
Externí odkaz:
https://doaj.org/article/0e7fe2937927407cbebd3d4c244d9741
Autor:
Manuela C. Aguirre-Botero, Eduardo Aliprandini, Anisha Gladston, Olga Pacios, Rafael Miyazawa Martins, Jean-Luc Poyet, Rogerio Amino
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 480 (2024)
Membranolytic molecules constitute the first line of innate immune defense against pathogenic microorganisms. Plasmodium sporozoites are potentially exposed to these cytotoxic molecules in the hemolymph and salivary glands of mosquitoes, as well as i
Externí odkaz:
https://doaj.org/article/4f5d4429d3264601ad82e325d1de34de
Autor:
Selma Belhimeur, Sylvie Briquet, Roger Peronet, Jennifer Pham, Pierre-Henri Commere, Pauline Formaglio, Rogerio Amino, Artur Scherf, Olivier Silvie, Salaheddine Mecheri
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPlasmodium sporozoites (SPZ) inoculated by Anopheles mosquitoes into the skin of the mammalian host migrate to the liver before infecting hepatocytes. Previous work demonstrated that early production of IL-6 in the liver is detrimental fo
Externí odkaz:
https://doaj.org/article/e6990ab4637447d6accce1152de062d0
Autor:
Adéla Nacer, Gaily Kivi, Raini Pert, Erkki Juronen, Pavlo Holenya, Eduardo Aliprandini, Rogerio Amino, Olivier Silvie, Doris Quinkert, Yann Le Duff, Matthew Hurley, Ulf Reimer, Andres Tover, Simon J. Draper, Sarah Gilbert, Mei Mei Ho, Paul W. Bowyer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Malaria, an infection caused by apicomplexan parasites of the genus Plasmodium, continues to exact a significant toll on public health with over 200 million cases world-wide, and annual deaths in excess of 600,000. Considerable progress has been made
Externí odkaz:
https://doaj.org/article/964ca94ca03a4486ab7310ec1cba72cb
Autor:
Matthias Paulus Wagner, Pauline Formaglio, Olivier Gorgette, Jerzy Michal Dziekan, Christèle Huon, Isabell Berneburg, Stefan Rahlfs, Jean-Christophe Barale, Sheldon I. Feinstein, Aron B. Fisher, Didier Ménard, Zbynek Bozdech, Rogerio Amino, Lhousseine Touqui, Chetan E. Chitnis
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110923- (2022)
Summary: The uptake and digestion of host hemoglobin by malaria parasites during blood-stage growth leads to significant oxidative damage of membrane lipids. Repair of lipid peroxidation damage is crucial for parasite survival. Here, we demonstrate t
Externí odkaz:
https://doaj.org/article/19eda5da865f4a5c9cee9657e6e2cb8f
Autor:
Johanna Ripp, Jessica Kehrer, Xanthoula Smyrnakou, Nathalie Tisch, Joana Tavares, Rogerio Amino, Carmen Ruiz de Almodovar, Friedrich Frischknecht
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp 1-10 (2021)
Abstract Transmission of malaria‐causing parasites to and by the mosquito relies on active parasite migration and constitutes bottlenecks in the Plasmodium life cycle. Parasite adaption to the biochemically and physically different environments mus
Externí odkaz:
https://doaj.org/article/63f1ac9b587f4af5846981f633ee39af
Autor:
Anthony A. Ruberto, Caitlin Bourke, Nicolas Merienne, Thomas Obadia, Rogerio Amino, Ivo Mueller
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract In the malaria-causing parasite’s life cycle, Plasmodium sporozoites must travel from the midgut of a mosquito to the salivary glands before they can infect a mammalian host. However, only a fraction of sporozoites complete the journey. Si
Externí odkaz:
https://doaj.org/article/3ed21ec8665144f28e647dfbfbc05286
Autor:
Ana Rafaela Teixeira, Begoña Pérez-Cabezas, David M. Costa, Mónica Sá, Sylvain Golba, Hélèna Sefiane-Djemaoune, Joana Ribeiro, Izumi Kaneko, Shiroh Iwanaga, Masao Yuda, Moriya Tsuji, Silvia Beatriz Boscardin, Rogerio Amino, Anabela Cordeiro-da-Silva, Joana Tavares
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Malaria is a major public health concern, as a highly effective human vaccine remains elusive. The efficacy of a subunit vaccine targeting the most abundant protein of the sporozoite surface, the circumsporozoite protein (CSP) has been hindered by di
Externí odkaz:
https://doaj.org/article/39b48b40b8af477b896617e5648234ba