Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rofeamor P. Obena"'
Autor:
Rofeamor P. Obena, Dvir Rotem, Aaron James F. Reyes, Shir Elbaz, Roman Zhuravel, Shlomo Yitzchaik, Einav Amit, Danny Porath, Yu-Ju Chen, Yi-Ting Wang, Assaf Friedler
Publikováno v:
Chemical Science. 6:4756-4766
We present an integrated approach for highly sensitive identification and validation of substrate-specific kinases as cancer biomarkers. Our approach combines phosphoproteomics for high throughput cancer-related biomarker discovery from patient tissu
Autor:
Chi-Ling Chen, Chih-Hsiang Chang, Yu-Ju Chen, Wei-Chun Chen, Tung-Hung Su, Rofeamor P. Obena, Pei-Jer Chen, Rey Y. Capangpangan, Yi-Ju Chen, Mira Anne C. dela Rosa
Publikováno v:
Analytical chemistry. 89(7)
We report a one-pot two-nanoprobe approach coupled to mass spectrometry for simultaneous quantification and post-translational modification (PTM) profiling of targeted protein in biofluid. Using N-glycoprotein as model, the assay employs two nanoprob
Autor:
Hong-Jie Dai, Rofeamor P. Obena, Yung-Yu Shih, Chi-Yang Wu, Nai-Wen Chang, Yen-Jen Oyang, Wen-Lian Hsu, Yu-Ju Chen, Mira Anne C. dela Rosa
Publikováno v:
Database: The Journal of Biological Databases and Curation
Hepatocellular carcinoma (HCC), one of the most common causes of cancer-related deaths, carries a 5-year survival rate of 18%, underscoring the need for robust biomarkers. In spite of the increased availability of HCC related literatures, many of the
Autor:
Ming-Feng Huang, Chung-Yi Wu, Yu-Ju Chen, Mei-Chun Tseng, Indah Primadona, Rey Y. Capangpangan, Yi-Sheng Wang, Shiou-Ting Li, Huan-Tsung Chang, Yin-Hung Lai, Chun-Cheng Lin, Wei-Ting Chien, Rofeamor P. Obena
Publikováno v:
The Analyst. 141(21)
Glycoconjugates are ubiquitously present and play a critical role in various biological processes. Due to their low stability and incredibly high degree of structural diversity, the structural characterization of glycan generally requires chemical de
Autor:
Rofeamor P. Obena, Rey Y. Capangpangan, Mira Anne C. dela Rosa, Ming-Hsi Chiang, Yu-jen Chou, Der-Lii M. Tzou, Shao-Ju Shih, Chun-Cheng Lin, Yu-Ju Chen
Publikováno v:
The Analyst. 140(22)
To enhance the detection sensitivity of target clinical protein biomarkers, a simple and rapid nanoprobe-based immuno-affinity mass spectrometry assay employing biocompatible monodisperse magnetic nanoparticles (MNPs) is reported herein. The MNPs wer
Autor:
Rofeamor P. Obena, Indah Primadona, Yu-Ju Chen, Rey Y. Capangpangan, I-Che Li, Wan-Sheung Li, Hsiu-Fong Lu, Chun-Cheng Lin, Mei-Chun Tseng, Ito Chao, Jun Hsiao
Publikováno v:
Chemical Science
Our work highlights DHB@MNP-induced pseudo-MS/MS for oligosaccharide characterization, with some insights on this nanoparticle-mediated energy transfer dynamics.
The structure-specific fragmentation of gas-phase ions in tandem mass spectrometry
The structure-specific fragmentation of gas-phase ions in tandem mass spectrometry
Publikováno v:
The Analyst. 139(4)
Protein glycosylation has received increased attention for its critical role in cell biology and diseases. Developing new methodologies to discern phenotype-dependent glycosylation will not only elucidate the mechanistic aspects of cell signaling cas
Autor:
I-Che Li, Ying-Wei Lu, Chung-Chen Lin, Florian R. del Mundo, Guillermo Nuesca, Rofeamor P. Obena, Po-Chiao Lin, Yu-Ju Chen, Susan D. Arco
Publikováno v:
Analytical chemistry. 83(24)
The significance and epidemiological effects of metals to life necessitate the development of direct, efficient, and rapid method of analysis. Taking advantage of its simple, fast, and high-throughput features, we present a novel approach to metal io
Autor:
Ying-Wei Lu, Chun-Cheng Lin, Ping-Yu Lin, Mei-Chun Tseng, Yen Yung-Sheng, Jiann-Tsuen Lin, Po-Chiao Lin, Kuang-Lieh Lu, Long-Li Lai, Yu-Ju Chen, Li-De Huang, Rofeamor P. Obena
Publikováno v:
Journal of the American Society for Mass Spectrometry. 21(11)
Efficient structural characterization is important for quality control when developing novel materials. In this study, we demonstrated the soft ionization capability of the hybrid of immobilized silica and 2,5-dihydrobenzoic acid (DHB) on iron oxide