Personalized medicine for patients with COPD: where are we?

Autor: Franssen FME, Alter P, Bar N, Benedikter BJ, Iurato S, Maier D, Maxheim M, Roessler FK, Spruit MA, Vogelmeier CF, Wouters EFM, Schmeck B

Publikováno v: International Journal of COPD, Vol Volume 14, Pp 1465-1484 (2019)

Frits ME Franssen1,2, Peter Alter,3 Nadav Bar,4 Birke J Benedikter5,6, Stella Iurato,7 Dieter Maier,8 Michael Maxheim,3 Fabienne K Roessler,4 Martijn A Spruit,1–2,9 Claus F Vogelmeier,3 Emiel FM Wouters1,2, Bernd Schmeck3,5 On behalf of the SysMed

Externí odkaz: https://doaj.org/article/fb150424839247308795fab751df2a03

Noradrenaline release from the locus coeruleus shapes stress-induced hippocampal gene expression.

Autor: Privitera M; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH Zurich and University of Zurich, Switzerland, Zurich, Switzerland., von Ziegler LM; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH Zurich and University of Zurich, Switzerland, Zurich, Switzerland., Floriou-Servou A; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH Zurich and University of Zurich, Switzerland, Zurich, Switzerland., Duss SN; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH Zurich and University of Zurich, Switzerland, Zurich, Switzerland., Zhang R; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Waag R; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH Zurich and University of Zurich, Switzerland, Zurich, Switzerland., Leimbacher S; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Sturman O; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH Zurich and University of Zurich, Switzerland, Zurich, Switzerland., Roessler FK; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Heylen A; Laboratory of Neurochemistry and Behavior, Experimental Neurobiology Unit, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Vermeiren Y; Laboratory of Neurochemistry and Behavior, Experimental Neurobiology Unit, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Division of Human Nutrition and Health, Chair Group of Nutritional Biology, Wageningen University & Research (WUR), Wageningen, Netherlands., Van Dam D; Laboratory of Neurochemistry and Behavior, Experimental Neurobiology Unit, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Department of Neurology and Alzheimer Center, University of Groningen and University Medical Center Groningen (UMCG), Groningen, Netherlands., De Deyn PP; Laboratory of Neurochemistry and Behavior, Experimental Neurobiology Unit, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Department of Neurology and Alzheimer Center, University of Groningen and University Medical Center Groningen (UMCG), Groningen, Netherlands.; Department of Neurology, Memory Clinic of Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken, Antwerp, Belgium., Germain PL; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH Zurich and University of Zurich, Switzerland, Zurich, Switzerland.; Computational Neurogenomics, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zürich, Zurich, Switzerland.; Laboratory of Statistical Bioinformatics, University of Zürich, Zürich, Switzerland., Bohacek J; Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH Zurich and University of Zurich, Switzerland, Zurich, Switzerland.

Publikováno v: ELife [Elife] 2024 Mar 13; Vol. 12. Date of Electronic Publication: 2024 Mar 13.

Direct R-Loop Visualization on Genomic DNA by Native Automated Electron Microscopy.

Autor: Stoy H; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland., Luethi J; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.; Center for Microscopy and Image Analysis, University of Zurich, Zurich, Switzerland.; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Roessler FK; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.; Center for Microscopy and Image Analysis, University of Zurich, Zurich, Switzerland.; Department of Chemical Engineering, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Riemann J; Center for Microscopy and Image Analysis, University of Zurich, Zurich, Switzerland., Kaech A; Center for Microscopy and Image Analysis, University of Zurich, Zurich, Switzerland., Lopes M; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland. lopes@imcr.uzh.ch.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2528, pp. 1-20.

ATR-Mediated Global Fork Slowing and Reversal Assist Fork Traverse and Prevent Chromosomal Breakage at DNA Interstrand Cross-Links.

Autor: Mutreja K; Institute of Molecular Cancer Research, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Krietsch J; Institute of Molecular Cancer Research, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Hess J; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Ursich S; Institute of Molecular Cancer Research, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Berti M; Institute of Molecular Cancer Research, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Roessler FK; Institute of Molecular Cancer Research, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland; Center for Microscopy and Image Analysis, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Zellweger R; Institute of Molecular Cancer Research, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Patra M; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Gasser G; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Lopes M; Institute of Molecular Cancer Research, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. Electronic address: lopes@imcr.uzh.ch.

Publikováno v: Cell reports [Cell Rep] 2018 Sep 04; Vol. 24 (10), pp. 2629-2642.e5.