Výsledky vyhledávání - "Roemer Klaus"

Akademický článek

Resistance of mitochondrial p53 to dominant inhibition

Autor: Mestres Pedro, Armbruester Vivienne, Mueller Daniel, Schmitt Katrin, Heyne Kristina, Roemer Klaus

Publikováno v: Molecular Cancer, Vol 7, Iss 1, p 54 (2008)

Abstract Background Mutation of a tumor suppressor allele leaves the second as backup. Not necessarily so with p53. This homo-tetrameric transcription factor can become contaminated with mutant p53 through hetero-tetramerization. In addition, it can

Externí odkaz: https://doaj.org/article/2f24e5c982dd403297f1842a51063f10

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Akademický článek

MDM2 gene SNP309 T/G and p53 gene SNP72 G/C do not influence diffuse large B-cell non-Hodgkin lymphoma onset or survival in central European Caucasians

Autor: Landt Olfert, Truemper Lorenz, Kreuz Markus, Kerschenmeyer Lynn, Mueller Monika, Wabo Alain, Parisot Frédérique, Bittenbring Joerg, Menzel Alain, Pfreundschuh Michael, Roemer Klaus

Publikováno v: BMC Cancer, Vol 8, Iss 1, p 116 (2008)

Abstract Background SNP309 T/G (rs2279744) causes higher levels of MDM2, the most important negative regulator of the p53 tumor suppressor. SNP72 G/C (rs1042522) gives rise to a p53 protein with a greatly reduced capacity to induce apoptosis. Both po

Externí odkaz: https://doaj.org/article/6e2a650d068c4e87b02ece5751509410

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Akademický článek

Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells

Autor: Roemer Klaus, Köhler Hans, Mahyar-Roemer Mojgan

Publikováno v: BMC Cancer, Vol 2, Iss 1, p 27 (2002)

Abstract Background The natural plant polyphenol resveratrol present in some foods including grapes, wine, and peanuts, has been implicated in the inhibition, delay, and reversion of cellular events associated with heart diseases and tumorigenesis. R

Externí odkaz: https://doaj.org/article/c8d3f705213c45669c875037436826f5

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