Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Roelof Oosting"'
Publikováno v:
Toxicologie Analytique et Clinique. 34:S45-S46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31c54e007a255c7ccb5aa4561dba65d7
https://doi.org/10.1016/j.toxac.2022.06.050
https://doi.org/10.1016/j.toxac.2022.06.050
Publikováno v:
Forensic Science International. 256:38-41
Introduction Toxicological findings in deaths by asphyxiation due to a pure inert gas like helium are rare. We present three suicide cases of asphyxial death attributed to anoxia caused by inhalation of helium in a plastic bag positioned over the hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be610e971fae5c6fb3baadeab6b33a9d
https://doi.org/10.1016/j.forsciint.2015.06.028
https://doi.org/10.1016/j.forsciint.2015.06.028
Autor:
Klaas J. Lusthof, A. Maes, Miranda Verschraagen, Annette Sprong, Roelof Oosting, Albert Dijkhuizen
Publikováno v:
Forensic Science International. 206:e93-e95
A 36-year old man, having injured himself severely by smashing windows in a rage of fury, was arrested by the police. He died despite resuscitation attempts. The forensic autopsy showed many superficial skin lacerations, bruises and minor brain swell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e599932bf50ebeb38920453b325557
https://doi.org/10.1016/j.forsciint.2010.12.014
https://doi.org/10.1016/j.forsciint.2010.12.014
Publikováno v:
Toxicology and Applied Pharmacology. 159:214-223
The formation of glutathione (GSH) conjugates of racemic 4-hydroxy-trans-2,3-nonenal (4-HNE) in the rat in vivo in the perfused rat liver and rat erythrocytes has been studied. An HPLC system was developed for the assay of 4-HNE-glutathione conjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634559d22d6eca7122f60f314a60a096
https://doi.org/10.1006/taap.1999.8742
https://doi.org/10.1006/taap.1999.8742
Publikováno v:
British Journal of Pharmacology. 123:361-370
In the present study it was tested whether known P-glycoprotein (P-gp) substrates/MDR reversal agents interact with small (type 1) and bulky (type 2) cationic drugs at the level of biliary excretion in the rat isolated perfused liver model (IPRL). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::026920ff2bbc93e1577f968f5d46cc9e
https://doi.org/10.1038/sj.bjp.0701606
https://doi.org/10.1038/sj.bjp.0701606
Publikováno v:
Pharmaceutical Research. 11:144-150
The hepatic disposition of two glycosidase inhibitors was studied in the isolated perfused rat liver and after subcellular fractionation. The mannosidase inhibitor 1-deoxymannojirimycin (dMM) and the glucosidase inhibitor N-methyl-1-deoxynojirimycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9eedc1049a37a66d3dae564b8969884
https://doi.org/10.1023/a:1018970400323
https://doi.org/10.1023/a:1018970400323
Autor:
A. H. J. Scaf, Wim E.M. Mol, Jan E. Paanakker, Ferdie Rombout, Roelof Oosting, Dirk K. F. Meijer
Publikováno v:
Biochemical Pharmacology. 44:1453-1459
Both in humans and animals hepatic elimination is an important factor determining the duration of action of non-depolarizing neuromuscular blocking drugs. To elucidate the hepato-biliary disposition of muscle relaxants the pharmacokinetics of several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd05f4c3747e820752dfccb4ec247937
https://doi.org/10.1016/0006-2952(92)90548-w
https://doi.org/10.1016/0006-2952(92)90548-w
Publikováno v:
Pharmaceutical Research. :1442-1450
We studied the pharmacokinetics of two synthetic derivatives of 1-deoxynojirimycin in the rat after intravenous administration. The mannosidase IA/B inhibitor 1-deoxymannojirimycin and the glucosidase inhibitor N-methyl- 1-deoxynojirimycin exhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::516c251fe5b01f7a0ddd645b5ae47419
https://doi.org/10.1023/a:1015810913257
https://doi.org/10.1023/a:1015810913257
Autor:
Roelof Oosting, Machiel J. Hardonk, Grietje Molema, Rw Jansen, T. L. Ching, Frits Moolenaar, G Harms, Dkf Meijer
Publikováno v:
Journal of Biological Chemistry. 266:3343-3348
We synthesized several para-aminophenyl (pap-) mannose-terminated albumins with varying sugar density (Man7-HSA, Man22-HSA, and Man40-HSA) and compared hepatic uptake with (thio-)mannose-terminated bovine serum albumin (Man-43-AI-BSA) The rate of upt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5a9d2da1f38f03ecb96735dca6b57b9
https://doi.org/10.1016/s0021-9258(18)49994-2
https://doi.org/10.1016/s0021-9258(18)49994-2
Autor:
Henderik W. Frijlink, Roelof Oosting, Eric J. F. Franssen, Anko C. Eissens, Dirk K. F. Meijer, Coenraad F. Lerk
Publikováno v:
Pharmaceutical Research. :380-384
Naproxen and flurbiprofen form complexes with hydroxypropyl-beta-cyclodextrin; with stability constants of 2207 and 12515 M-1, respectively. However, only small fractions of the drug remain complexed when the drug-cyclodextrin complex is added to pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38a0ccab8e508af6bd5d475972fd1bc5
https://doi.org/10.1023/a:1015857902238
https://doi.org/10.1023/a:1015857902238