Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Roelof A. de Paus"'
1
Akademický článek
Complement Component C1q as Serum Biomarker to Detect Active Tuberculosis
Autor: Rosalie Lubbers, Jayne S. Sutherland, Delia Goletti, Roelof A. de Paus, Coline H. M. van Moorsel, Marcel Veltkamp, Stefan M. T. Vestjens, Willem J. W. Bos, Linda Petrone, Franca Del Nonno, Ingeborg M. Bajema, Karin Dijkman, Frank A. W. Verreck, Gerhard Walzl, Kyra A. Gelderman, Geert H. Groeneveld, Annemieke Geluk, Tom H. M. Ottenhoff, Simone A. Joosten, Leendert A. Trouw
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
Background: Tuberculosis (TB) remains a major threat to global health. Currently, diagnosis of active TB is hampered by the lack of specific biomarkers that discriminate active TB disease from other (lung) diseases or latent TB infection (LTBI). Inte
Externí odkaz: https://doaj.org/article/284ee675f05148ea83612a8c2d040f94
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2
Akademický článek
Impaired Immune Response to Primary but Not to Booster Vaccination Against Hepatitis B in Older Adults
Autor: Birgit Weinberger, Mariëlle C. Haks, Roelof A. de Paus, Tom H. M. Ottenhoff, Tanja Bauer, Beatrix Grubeck-Loebenstein
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
Many current vaccines are less immunogenic and less effective in elderly compared to younger adults due to age-related changes of the immune system. Most vaccines utilized in the elderly contain antigens, which the target population has had previous
Externí odkaz: https://doaj.org/article/8a8ef6d33ea84626871061232ef968c8
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3
Cross-laboratory evaluation of multiplex bead assays including independent common reference standards for immunological monitoring of observational and interventional human studies
Autor: Anne M. F. H. Drittij, Mei M. Ho, Helen McShane, Bhagwati Khatri, Steven G. Smith, Jelle J. Goeman, Hazel M. Dockrell, Krista E. van Meijgaarden, Simone A. Joosten, Tom H. M. Ottenhoff, Roelof A. de Paus
Publikováno v: PLoS ONE, 13(9)
PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0201205 (2018)
© 2018 van Meijgaarden et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and sour
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73a2355c8963bc9607e7640f7a77a1e
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4
Impaired Immune Response to Primary but Not to Booster Vaccination Against Hepatitis B in Older Adults
Autor: Mariëlle C. Haks, Roelof A. de Paus, Tom H. M. Ottenhoff, Tanja Bauer, Birgit Weinberger, Beatrix Grubeck-Loebenstein
Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, 9
Front. Immunol. 9:1035 (2018)
Many current vaccines are less immunogenic and less effective in elderly compared to younger adults due to age-related changes of the immune system. Most vaccines utilized in the elderly contain antigens, which the target population has had previous
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40c87ec7e4d9bbd18b455020ea01b4f
https://doi.org/10.3389/fimmu.2018.01035
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5
Immunological characterization of latent tuberculosis infection in a low endemic country
Autor: Margreet H. Kamphorst, Sandra M. Arend, Tom H. M. Ottenhoff, Roelof A. de Paus, Krista E. van Meijgaarden, Simone A. Joosten, Corine Prins
Publikováno v: Tuberculosis, 106, 62-72
The diagnosis of a latent tuberculosis infection (LTBI) is based on detection of immunity against Mycobacterium tuberculosis (Mtb). The tuberculin skin test (TST), the Quantiferon (QFT) and a prolonged lymphocyte stimulation test using either ESAT-6/
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d148d6de461ff8d5ad9049c0e7926d0d
http://hdl.handle.net/1887/115051
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6
IL-23 modulates CD56+/CD3- NK Cell and CD56+/CD3+ NK-like T Cell function differentially from IL-12
Autor: Diederik van de Wetering, Jaap T. van Dissel, Esther van de Vosse, Roelof A. de Paus
Publikováno v: International Immunology. 21:145-153
NK and NK-like T cells play an essential role in linking innate and adaptive immunity through their ability to secrete IFN-gamma. The exact trigger initiating production of IFN-gamma is uncertain. Antigen-presenting cell (APC)-derived IL-12 is though
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbda1c8994225bd26b289fec2e119056
https://doi.org/10.1093/intimm/dxn132
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7
IL-23 and IL-12 responses in activated human T cells retrovirally transduced with IL-23 receptor variants
Autor: Esther van de Vosse, Jaap T. van Dissel, Roelof A. de Paus, Diederik van de Wetering
Publikováno v: Molecular Immunology. 45:3889-3895
Interleukin-23 (IL-23) is a regulator of cellular immune responses involved in controlling infections and autoimmune diseases. Effects of IL-23 on T cells are mediated via a receptor complex consisting of an IL-12Rbeta1 and a specific IL-23R chain. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10ef19d17c5093d4645762a31c68378
https://doi.org/10.1016/j.molimm.2008.06.029
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8
Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved alpha joining region
Autor: Roelof A. de Paus, Mirjam H.M. Heemskerk, Els Goulmy, J.H. Frederik Falkenburg, Roel Willemze, Menno A. W. G. van der Hoorn, Michel G.D. Kester, Manja Hoogeboom
Publikováno v: Blood. 102:3530-3540
Donor-derived T lymphocytes directed against minor histocompatibility antigens (mHags) exclusively expressed on cells of the hematopoietic lineages can eliminate hematologic malignancies. Transfer of T-cell receptors (TCRs) directed against these mHa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ee884897d0677bc9f924ac69f13719
https://doi.org/10.1182/blood-2003-05-1524
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10
The influence of influenza virus infections on the development of tuberculosis
Autor: Reinout van Crevel, Sangkot Marzuki, Roelof A. de Paus, Bachti Alisjahbana, Tom H. M. Ottenhoff, Esther van de Vosse, Ruud van Beek, Jaap T. van Dissel, Edhyana Sahiratmadja, Guus F. Rimmelzwaan
Publikováno v: Tuberculosis; Vol 93
Tuberculosis, 93, 3, pp. 338-42
Tuberculosis, 93(3), 338-342. Churchill Livingstone
Tuberculosis
Tuberculosis, 93, 338-42
Recently, it was shown that interferon-gamma mediated immune responses, which play a major role in the control of infection with Mycobacterium tuberculosis (Mtb), can be inhibited by type I interferons. Since type I interferons are abundantly induced
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7029286abd74fece2ad3601f9262347b
http://hdl.handle.net/1887/97490
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