Zobrazeno 1 - 10
of 645
pro vyhledávání: '"Roeland E"'
Autor:
Jorge Alemán-Báez, Jose Fernando Acevedo-Zamora, Johan Bucher, Chengcheng Cai, Roeland E. Voorrips, Guusje Bonnema
Publikováno v:
Horticultural Plant Journal, Vol 10, Iss 4, Pp 1007-1019 (2024)
The vegetative development of cabbage (Brassica oleracea var. capitata) passes through seedling, rosette, folding and heading stages. Leaves that form the rosette are large and mostly flat. In the following developmental stages, the plants produce le
Externí odkaz:
https://doaj.org/article/e9b2e23520104e38a0903d9eedb81009
Autor:
Aida N. Kawuma, Roeland E. Wasmann, Phumla Sinxadi, Simiso M. Sokhela, Nomathemba Chandiwana, Willem D. F. Venter, Lubbe Wiesner, Gary Maartens, Paolo Denti
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 6, Pp 821-830 (2023)
Abstract Tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) are prodrugs of the nucleotide analogue tenofovir, which acts intracellularly to inhibit HIV replication. Whereas TDF converts to tenofovir in plasma and may cause kidney an
Externí odkaz:
https://doaj.org/article/d0c5aa5d4d6040aa8aeab8553a6989ac
Autor:
Lufina Tsirizani Galileya, Roeland E Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F Cotton, Helen McIlleron, Paolo Denti
Publikováno v:
PLoS Medicine, Vol 20, Iss 11, p e1004303 (2023)
BackgroundThe current World Health Organization (WHO) pediatric tuberculosis dosing guidelines lead to suboptimal drug exposures. Identifying factors altering the exposure of these drugs in children is essential for dose optimization. Pediatric pharm
Externí odkaz:
https://doaj.org/article/aa73b4c4db55463fb38f8af390a8ffa2
Autor:
Roeland E. Voorrips, Giorgio Tumino
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background For genetic analyses, multi-allelic markers have an advantage over bi-allelic markers like SNPs (single nucleotide polymorphisms) in that they carry more information about the genetic constitution of individuals. This is especiall
Externí odkaz:
https://doaj.org/article/ca3a2a722853435c91992caf5ec626df
Autor:
Roeland E. Wasmann, Tiziana Masini, Kerri Viney, Sabine Verkuijl, Annemieke Brands, Anneke C. Hesseling, Helen McIlleron, Paolo Denti, Kelly E. Dooley
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Following infection with Mycobacterium tuberculosis, young children are at high risk of developing severe forms of tuberculosis (TB) disease, including TB meningitis (TBM), which is associated with significant morbidity and mortality. In 2022, the Wo
Externí odkaz:
https://doaj.org/article/7d5f5eb528d14b1ea543e2e421c070cb
Autor:
Alejandro Thérèse Navarro, Giorgio Tumino, Roeland E. Voorrips, Paul Arens, Marinus J. M. Smulders, Eric van de Weg, Chris Maliepaard
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Quantitative trait locus (QTL) analysis allows to identify regions responsible for a trait and to associate alleles with their effect on phenotypes. When using biallelic markers to find these QTL regions, two alleles per QTL are modelled. Th
Externí odkaz:
https://doaj.org/article/b86e93c1479d41b69b2d35655df3ec9b
Publikováno v:
Agronomy, Vol 13, Iss 5, p 1434 (2023)
Pepper (Capsicum spp.) is an important vegetable crop worldwide with high economic and nutritional value. The Capsicum genus comprises more than 30 species, of which C. annuum, C. chinense, C. baccatum, C. frutescens, and C. pubescens are the five do
Externí odkaz:
https://doaj.org/article/4312e286b82c4c868a807835aba34f7e
Autor:
Peter M. Bourke, Christine A. Hackett, Roeland E. Voorrips, Richard G. F. Visser, Chris Maliepaard
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2107-2122 (2019)
New genotyping technologies, offering the possibility of high genetic resolution at low cost, have helped fuel a surge in interest in the genetic analysis of polyploid species. Nevertheless, autopolyploid species present extra challenges not encounte
Externí odkaz:
https://doaj.org/article/2bcc2d881f3b411ca55109236188bf86
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Genetic studies in tetraploids are lagging behind in comparison with studies of diploids as the complex genetics of tetraploids require much more elaborated computational methodologies. Recent advancements in development of molecu
Externí odkaz:
https://doaj.org/article/49eed4b9976341b2a12a464f14d00727
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 8 (2021)
AbstractUnreduced gametes (2n gametes), possessing double the haploid genome, whatever ploidy that happens to be, are a common source of ploidy variation in plant populations. First and second division restitution (FDR and SDR) are the dominant mecha
Externí odkaz:
https://doaj.org/article/bd8ca58634df4770ad95141bc5e54a1f