Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Roel P. H. De Maeyer"'
Autor:
Karen T. Feehan, Hannah E. Bridgewater, Jan Stenkiewicz-Witeska, Roel P. H. De Maeyer, John Ferguson, Matthias Mack, Jeremy Brown, Giuseppe Ercoli, Connar M. Mawer, Arne N. Akbar, James R. W. Glanville, Parinaaz Jalali, Olivia V. Bracken, Anna Nicolaou, Alexandra C. Kendall, Michelle A. Sugimoto, Derek W. Gilroy
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Resolving inflammation is thought to return the affected tissue back to homoeostasis but recent evidence supports a non-linear model of resolution involving a phase of prolonged immune activity. Here we show that within days following resolu
Externí odkaz:
https://doaj.org/article/2c3602528dd144b09810421a90f86c86
Autor:
David R. Pearce, Ayse U. Akarca, Roel P. H. De Maeyer, Emily Kostina, Ariana Huebner, Monica Sivakumar, Takahiro Karasaki, Kavina Shah, Sam M. Janes, Nicholas McGranahan, Venkat Reddy, Arne N. Akbar, David A. Moore, Teresa Marafioti, Charles Swanton, Robert E. Hynds
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundPatient-derived xenograft (PDX) models involve the engraftment of tumour tissue in immunocompromised mice and represent an important pre-clinical oncology research method. A limitation of non-small cell lung cancer (NSCLC) PDX model derivat
Externí odkaz:
https://doaj.org/article/cae9afdbf4674ceea00f1d3863b707db
Autor:
Roel P H, De Maeyer, Derek W, Gilroy
Publikováno v:
Nature metabolism. 4(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bae0baa865cf77091fff6c0210880513
https://pubmed.ncbi.nlm.nih.gov/35361955
https://pubmed.ncbi.nlm.nih.gov/35361955
Autor:
Roel P H, De Maeyer, Rachel C, van de Merwe, Rikah, Louie, Olivia V, Bracken, Oliver P, Devine, Daniel R, Goldstein, Mohib, Uddin, Arne N, Akbar, Derek W, Gilroy
Publikováno v:
Nature immunology. 21(6)
Increasing age alters innate immune-mediated responses; however, the mechanisms underpinning these changes in humans are not fully understood. Using a human dermal model of acute inflammation, we found that, although inflammatory onset is similar bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c948dc57aee78171889abed1b71f15d8
https://pubmed.ncbi.nlm.nih.gov/32303726
https://pubmed.ncbi.nlm.nih.gov/32303726
Autor:
Justine, Newson, Madhur P, Motwani, Alexandra C, Kendall, Anna, Nicolaou, Giulio G, Muccioli, Mireille, Alhouayek, Melanie, Bennett, Rachel, Van De Merwe, Sarah, James, Roel P H, De Maeyer, Derek W, Gilroy
Publikováno v:
Cell Reports
Summary Acute inflammation is characterized by granulocyte infiltration followed by efferocytosing mononuclear phagocytes, which pave the way for inflammatory resolution. Until now, it was believed that resolution then leads back to homeostasis, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf767bc118c0131cf1094d24f69e951b
https://pubmed.ncbi.nlm.nih.gov/28954232
https://pubmed.ncbi.nlm.nih.gov/28954232
Autor:
Derek W, Gilroy, Matthew L, Edin, Roel P H, De Maeyer, Jonas, Bystrom, Justine, Newson, Fred B, Lih, Melanie, Stables, Darryl C, Zeldin, David, Bishop-Bailey
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(23)
Resolution of inflammation has emerged as an active process in immunobiology, with cells of the mononuclear phagocyte system being critical in mediating efferocytosis and wound debridement and bridging the gap between innate and adaptive immunity. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa84ba654cf16e1fd2fed754b1090015
https://pubmed.ncbi.nlm.nih.gov/27226306
https://pubmed.ncbi.nlm.nih.gov/27226306
Autor:
James N, Fullerton, Elisabetta, Segre, Roel P H, De Maeyer, Alexander A N, Maini, Derek W, Gilroy
Publikováno v:
Journal of Visualized Experiments : JoVE
Activation of inflammatory pathways represents a central mechanism in multiple disease states both acute and chronic. Triggered via either pathogen or tissue damage-associated molecular motifs, common biochemical pathways lead to conserved yet variab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49ba93af0cde08ea0cf7e26957caa569
https://pubmed.ncbi.nlm.nih.gov/27213711
https://pubmed.ncbi.nlm.nih.gov/27213711
Autor:
Feehan, Karen T., Bridgewater, Hannah E., Stenkiewicz-Witeska, Jan, De Maeyer, Roel P. H., Ferguson, John, Mack, Matthias, Brown, Jeremy, Ercoli, Giuseppe, Mawer, Connar M., Akbar, Arne N., Glanville, James R. W., Jalali, Parinaaz, Bracken, Olivia V., Nicolaou, Anna, Kendall, Alexandra C., Sugimoto, Michelle A., Gilroy, Derek W.
Publikováno v:
Nature Communications; 5/21/2024, Vol. 15 Issue 1, p1-17, 17p
Autor:
Falih, Israa Qusay1 israaqusai@uomisan.edu.iq, Tahir, Noor Thair2 dr.noorthair.ndc@uomustansiriyah.edu.iq, Alkubaisi, Mithal R.3
Publikováno v:
Jordan Journal of Biological Sciences. Jun2022, Vol. 15 Issue 3, p423-429. 7p.
Autor:
Covre, Luciana P.1,2 (AUTHOR), De Maeyer, Roel P. H.1 (AUTHOR), Gomes, Daniel C. O.2 (AUTHOR) dgomes@ndi.ufes.br, Akbar, Arne N.1 (AUTHOR) a.akbar@ucl.ac.uk
Publikováno v:
Aging Cell. Dec2020, Vol. 19 Issue 12, p1-9. 9p.