Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Roel P F Schins"'
Autor:
Verena Wilhelmi, Ute Fischer, Heike Weighardt, Klaus Schulze-Osthoff, Carmen Nickel, Burkhard Stahlmecke, Thomas A J Kuhlbusch, Agnes M Scherbart, Charlotte Esser, Roel P F Schins, Catrin Albrecht
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65704 (2013)
In view of the steadily increasing use of zinc oxide nanoparticles in various industrial and consumer applications, toxicological investigations to evaluate their safety are highly justified. We have investigated mechanisms of ZnO nanoparticle-induce
Externí odkaz:
https://doaj.org/article/46b48c391f7440b282f572247b23628e
Publikováno v:
Swiss Medical Weekly, Vol 142, Iss 4546 (2012)
After the health catastrophe resulting from the widespread use of asbestos which was once hailed as a new miracle material, the increasing use of carbon nanotubes (CNTs) has spawned major concern due to their similarities in terms of size, shape and
Externí odkaz:
https://doaj.org/article/6091ef6ba0ae457f81980804f065ab77
Autor:
Torben Stermann, Thach Nguyen, Burkhard Stahlmecke, Ana Maria Todea, Selina Woeste, Inken Hacheney, Jean Krutmann, Klaus Unfried, Roel P. F. Schins, Andrea Rossi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Cystic fibrosis is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) that can lead to terminal respiratory failure. Ultrafine carbonaceous particles, which are ubiquitous in
Externí odkaz:
https://doaj.org/article/d7c64df7cb9a4ae78e391e5e35ce98aa
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The NLRP3 inflammasome plays an important role in intestinal homeostasis as well as inflammation. However, in vivo studies investigating the role of the NLRP3 inflammasome in inflammatory bowel disease (IBD) report contrasting results, leaving it unc
Externí odkaz:
https://doaj.org/article/2feabaf62b1d4f0b87f1a50d87d2a09c
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
As with toxicology in general, major challenges have emerged in its subfield neurotoxicology regarding the testing of engineered nanomaterials (ENM). This is on the one hand due to their complex physicochemical properties, like size, specific surface
Externí odkaz:
https://doaj.org/article/ab384bfe8a384a5eb368c5d245085a97
Autor:
Agnes W. Boots, Carmen Veith, Catrin Albrecht, Roger Bartholome, Marie-José Drittij, Sandra M. H. Claessen, Aalt Bast, Martin Rosenbruch, Leonie Jonkers, Frederik-Jan van Schooten, Roel P. F. Schins
Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic, lethal disease of which the etiology is still not fully understood. Current treatment comprises two FDA-approved drugs that can slow down yet not stop or reverse the disease. As IP
Externí odkaz:
https://doaj.org/article/ec960b18230d4e878b5617abf0ee4443
Autor:
Mathias Busch, Gerrit Bredeck, Friedrich Waag, Khosrow Rahimi, Haribaskar Ramachandran, Tobias Bessel, Stephan Barcikowski, Andreas Herrmann, Andrea Rossi, Roel P. F. Schins
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1095 (2022)
Due to the ubiquity of environmental micro- and nanoplastics (MNPs), inhalation and ingestion by humans is very likely, but human health effects remain largely unknown. The NLRP3 inflammasome is a key player of the innate immune system and is involve
Externí odkaz:
https://doaj.org/article/c6b82c6c1938420497951c92c1263b21
Autor:
Linda Elberskirch, Adriana Sofranko, Julia Liebing, Norbert Riefler, Kunigunde Binder, Christian Bonatto Minella, Matthias Razum, Lutz Mädler, Klaus Unfried, Roel P. F. Schins, Annette Kraegeloh, Christoph van Thriel
Publikováno v:
Nanomaterials, Vol 12, Iss 7, p 1053 (2022)
It has been widely recognized that nanosafety studies are limited in reproducibility, caused by missing or inadequate information and data gaps. Reliable and comprehensive studies should be performed supported by standards or guidelines, which need t
Externí odkaz:
https://doaj.org/article/8dd9b552a0d54a179664af8cfbaa422d
Autor:
Maja Hullmann, Catrin Albrecht, Damiën van Berlo, Miriam E. Gerlofs-Nijland, Tina Wahle, Agnes W. Boots, Jean Krutmann, Flemming R. Cassee, Thomas A. Bayer, Roel P. F. Schins
Publikováno v:
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-14 (2017)
Abstract Background Increasing evidence from toxicological and epidemiological studies indicates that the central nervous system is an important target for ambient air pollutants. We have investigated whether long-term inhalation exposure to diesel e
Externí odkaz:
https://doaj.org/article/b0c62015f660490993716ccc4dc3da7b
Autor:
Mathias Busch, Hugo Brouwer, Germaine Aalderink, Gerrit Bredeck, Angela A. M. Kämpfer, Roel P. F. Schins, Hans Bouwmeester
Publikováno v:
Frontiers in Toxicology. 5
Plastic particles in the nanometer range–called nanoplastics–are environmental contaminants with growing public health concern. As plastic particles are present in water, soil, air and food, human exposure via intestine and lung is unavoidable, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4daaa812b5d3cc7a33e87f271d822dcf
https://doi.org/10.3389/ftox.2023.1112212
https://doi.org/10.3389/ftox.2023.1112212