Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Roel Neijts"'
Autor:
Shilu Amin, Roel Neijts, Salvatore Simmini, Carina van Rooijen, Sander C. Tan, Lennart Kester, Alexander van Oudenaarden, Menno P. Creyghton, Jacqueline Deschamps
Publikováno v:
Cell Reports, Vol 17, Iss 12, Pp 3165-3177 (2016)
In vertebrate embryos, anterior tissues are generated early, followed by the other axial structures that emerge sequentially from a posterior growth zone. The genetic network driving posterior axial elongation in mice, and its disturbance in mutants
Externí odkaz:
https://doaj.org/article/4ab8ee6139bb4f9fa7f97daeb5e5aefe
Publikováno v:
FEBS Letters. 594(21):3439-3449
The three-dimensional organization of our genome is an important determinant for the transcriptional output of a gene in (patho)physiological contexts. The spatial organization of linear chromosomes within nucleus is dominantly inferred using two dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808d03af2171891ef69f4cadfbd21d09
https://hdl.handle.net/20.500.11755/fabbfbcb-d829-4a62-9d95-e293fdfef1c3
https://hdl.handle.net/20.500.11755/fabbfbcb-d829-4a62-9d95-e293fdfef1c3
Autor:
Roel Neijts, Jacqueline Deschamps
Publikováno v:
Developmental Biology, 428(2), 293-299. Academic Press
Developmental Biology, 428(2), 293. Academic Press Inc.
Developmental Biology, 428(2), 293. Academic Press Inc.
Hox genes are crucial players in the generation and pattering of the vertebrate trunk and posterior body during embryogenesis. Their initial expression takes place shortly after the establishment of the primitive streak, in the posterior-most part of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8138c457fca3b89ea7c4e4677977d70
https://doi.org/10.1016/j.ydbio.2017.02.009
https://doi.org/10.1016/j.ydbio.2017.02.009
Publikováno v:
Developmental Dynamics. 243:88-98
Background: The vertebrate body axis extends sequentially from the posterior tip of the embryo, fueled by the gastrulation process at the primitive streak and its continuation within the tailbud. Anterior structures are generated early, and subsequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a62447961b235eb73742a0c36a5a070
https://doi.org/10.1002/dvdy.24027
https://doi.org/10.1002/dvdy.24027
Publikováno v:
Developmental Biology. Academic Press
Developmental Biology, 422(2), 146. Academic Press Inc.
Developmental Biology, 422(2), 146. Academic Press Inc.
Cdx and Hox transcription factors are important regulators of axial patterning and are required for tissue generation along the vertebrate body axis. Cdx genes have been demonstrated to act upstream of Hox genes in midgestation embryos. Here, we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0900c092e7521f1544294dec6374a4c1
https://pure.knaw.nl/portal/en/publications/b58c0c7f-9853-4781-b442-37c037e807c3
https://pure.knaw.nl/portal/en/publications/b58c0c7f-9853-4781-b442-37c037e807c3
Autor:
Sander C. Tan, Wouter de Laat, Roel Neijts, Menno P. Creyghton, Shilu Amin, Jacqueline Deschamps, Carina van Rooijen
Publikováno v:
Genes and Development, 30(17), 1937. Cold Spring Harbor Laboratory Press
Genes & Development, 30(17), 1937-42. Cold Spring Harbor Laboratory Press
Genes & Development, 30(17), 1937-42. Cold Spring Harbor Laboratory Press
Sequential 3′-to-5′ activation of the Hox gene clusters in early embryos is a most fascinating issue in developmental biology. Neither the trigger nor the regulatory elements involved in the transcriptional initiation of the 3′-most Hox genes h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416797857625b42755ae8076889fcf9e
https://dspace.library.uu.nl/handle/1874/349286
https://dspace.library.uu.nl/handle/1874/349286
Autor:
Frank C. P. Holstege, Wadia H. Almirza, J. Peter H. Burbach, Elisa J. Hoekstra, Annemarie J. A. van der Linden, Marian J. A. Groot Koerkamp, Frank M. J. Jacobs, Dik van Leenen, Roel Neijts, Marten P. Smidt, Jesse V. Veenvliet, Lars von Oerthel
Publikováno v:
Development-The Company of Biologists, 138(23), 5213-5222. Company of Biologists Ltd
Development of meso-diencephalic dopamine (mdDA) neurons requires the combined actions of the orphan nuclear receptor Nurr1 and the paired-like homeobox transcription factor Pitx3. Whereas all mdDA neurons require Nurr1 for expression of Th and survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a12ed90a3b9d32b4cac243c28c3bf0
https://doi.org/10.1242/dev.071704
https://doi.org/10.1242/dev.071704
Autor:
Roel, Neijts, Salvatore, Simmini, Fabrizio, Giuliani, Carina, van Rooijen, Jacqueline, Deschamps
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 243(1)
The vertebrate body axis extends sequentially from the posterior tip of the embryo, fueled by the gastrulation process at the primitive streak and its continuation within the tailbud. Anterior structures are generated early, and subsequent nascent ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15a4ff26454c2f881235926777bd3d05
https://pubmed.ncbi.nlm.nih.gov/23913366
https://pubmed.ncbi.nlm.nih.gov/23913366
Autor:
Menno P. Creyghton, Shilu Amin, Jacqueline Deschamps, Alexander van Oudenaarden, Roel Neijts, Carina van Rooijen, Lennart Kester, Sander C. Tan, Salvatore Simmini
Publikováno v:
Cell Reports [E], 17(12), 3165. Cell Press
Cell Reports, Vol 17, Iss 12, Pp 3165-3177 (2016)
Cell Reports, 17(12), 3165-3177. Cell Press
Cell Reports, Vol 17, Iss 12, Pp 3165-3177 (2016)
Cell Reports, 17(12), 3165-3177. Cell Press
In vertebrate embryos, anterior tissues are generated early, followed by the other axial structures that emerge sequentially from a posterior growth zone. The genetic network driving posterior axial elongation in mice, and its disturbance in mutants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a12c049cc6cbe4f37f4cdcc0d88d24
https://doi.org/10.1016/j.celrep.2016.11.069
https://doi.org/10.1016/j.celrep.2016.11.069
Autor:
Monika Bialecka, Jacqueline Deschamps, Carina van Rooijen, Salvatore Simmini, Felix Beck, Cesca van de Ven, Roel Neijts
Publikováno v:
Development, 139(14), 2576-2583. Company of Biologists Ltd
Mouse Cdx genes are involved in axial patterning and partial Cdx mutants exhibit posterior embryonic defects. We found that mouse embryos in which all three Cdx genes are inactivated fail to generate any axial tissue beyond the cephalic and occipital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01432b6ef1d2e2f991c9a74b4ca44412
https://pure.knaw.nl/portal/en/publications/7b1033e9-02b0-4c5a-bf0f-922e131edb31
https://pure.knaw.nl/portal/en/publications/7b1033e9-02b0-4c5a-bf0f-922e131edb31