National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer

Autor: Johannes A. Langendijk, MD, PhD, Frank J. P. Hoebers, MD, PhD, Martin A. de Jong, MD, Patricia Doornaert, MD, PhD, Chris H. J. Terhaard, MD, PhD, Roel J. H. M. Steenbakkers, MD, PhD, Olga Hamming-Vrieze, MD, PhD, Jeroen B. van de Kamer, PhD, Wilko F. A. R. Verbakel, PhD, Fatma Keskin-Cambay, MD, Johannes B. Reitsma, MD, PhD, Arjen van der Schaaf, PhD, Liesbeth J. Boersma, MD, PhD, Ewoud Schuit, PhD

Publikováno v: International Journal of Particle Therapy, Vol 8, Iss 1, Pp 354-365 (2021)

In the Netherlands, the model-based approach is used to identify patients with head and neck cancer who may benefit most from proton therapy in terms of prevention of late radiation-induced side effects in comparison with photon therapy. To this purp

Externí odkaz: https://doaj.org/article/c42933b6792841108c4c14c899f0673e

Accurate segmentation of head and neck radiotherapy CT scans with 3D CNNs: consistency is key

Autor: Edward G A Henderson, Eliana M Vasquez Osorio, Marcel van Herk, Charlotte L Brouwer, Roel J H M Steenbakkers, Andrew F Green

Publikováno v: Henderson, E, Vasquez osorio, E, Van herk, M, Brouwer, C L, Steenbakkers, R J H M & Green, A F 2023, ' Accurate segmentation of head and neck radiotherapy CT scans with 3D CNNs: consistency is key ', Physics in Medicine & Biology . https://doi.org/10.1088/1361-6560/acc309
Physics in Medicine and Biology, 68(8):085003. IOP PUBLISHING LTD

Objective. Automatic segmentation of organs-at-risk in radiotherapy planning computed tomography (CT) scans using convolutional neural networks (CNNs) is an active research area. Very large datasets are usually required to train such CNN models. In r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b632f2baca56110ed3b62bfb6334fcee
https://research.manchester.ac.uk/en/publications/e013d333-a3f4-4cce-be5e-b875ca651d40

Validation of the

Autor: Yan, Li, N M, Sijtsema, S P M, de Vette, Roel J H M, Steenbakkers, Fan, Zhang, Walter, Noordzij, Lisa, Van den Bosch, J A, Langendijk, L V, van Dijk

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Previously, PET image biomarkers (PET-IBMs) - the 90thpercentile standardized uptake value (P90-SUV) and the Mean SUV (Mean-SUV) ofthe contralateral parotid gland (cPG) - were identified as predictors for late-xerostomiafollowing head and neck cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::809d4bd76ea7e76382433ba744383c4f
https://pubmed.ncbi.nlm.nih.gov/36608769

Development of advanced preselection tools to reduce redundant plan comparisons in model-based selection of head and neck cancer patients for proton therapy

Autor: E. Oldehinkel, Hans Paul van der Laan, J. Free, Wouter Rutgers, Tineke W.H. Meijer, Arjen van der Schaaf, D. Scandurra, Stefan Both, Makbule Tambas, Johanna G M van den Hoek, Johannes A. Langendijk, Roel J H M Steenbakkers

Publikováno v: Radiotherapy and Oncology
Radiotherapy and Oncology, 160, 61-68. ELSEVIER IRELAND LTD

PURPOSE: In the Netherlands, head and neck cancer (HNC) patients are selected for proton therapy (PT) based on estimated normal tissue complication probability differences (ΔNTCP) between photons and protons, which requires a plan comparison (VMAT v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06346e7a142339179cfac62122e07de
https://doi.org/10.1016/j.radonc.2021.04.012

Comprehensive toxicity risk profiling in radiation therapy for head and neck cancer: A new concept for individually optimised treatment

Autor: Karel G.M. Moons, Johanna G M van den Hoek, Lisa Van den Bosch, Oda B. Wijers, Johannes A. Langendijk, Johannes B. Reitsma, Roel J H M Steenbakkers, Hans Paul van der Laan, Ewoud Schuit, Arjen van der Schaaf, Frank J. P. Hoebers

Publikováno v: Radiotherapy and Oncology, 157, 147-154. Elsevier Ireland Ltd
Radiotherapy and oncology, 157, 147-154. Elsevier Ireland Ltd
Radiotherapy and Oncology, 157, 147-154. ELSEVIER IRELAND LTD

Background and purpose: A comprehensive individual toxicity risk profile is needed to improve radiation treatment optimisation, minimising toxicity burden, in head and neck cancer (HNC) patients. We aimed to develop and externally validate NTCP model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999b28924f4a7222ca9160f940b3c1e3
https://doi.org/10.1016/j.radonc.2021.01.024