Influence of Network Topology on the Viscoelastic Properties of Dynamically Crosslinked Hydrogels

Autor: Emilia M. Grad, Isabell Tunn, Dion Voerman, Alberto S. de Léon, Roel Hammink, Kerstin G. Blank

Publikováno v: Frontiers in Chemistry, Vol 8 (2020)

Biological materials combine stress relaxation and self-healing with non-linear stress-strain responses. These characteristic features are a direct result of hierarchical self-assembly, which often results in fiber-like architectures. Even though str

Externí odkaz: https://doaj.org/article/d8e92c5c44f84a32bdaa6285bccf20b0

Biomaterial-Based Activation and Expansion of Tumor-Specific T Cells

Autor: Marjolein Schluck, Roel Hammink, Carl G. Figdor, Martijn Verdoes, Jorieke Weiden

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Traditional tumor vaccination approaches mostly focus on activating dendritic cells (DCs) by providing them with a source of tumor antigens and/or adjuvants, which in turn activate tumor-reactive T cells. Novel biomaterial-based cancer immunotherapeu

Externí odkaz: https://doaj.org/article/22e9ff0fed3c496b8a9a42a5c478b9f0

Through-Space Stabilization of an Imidazolium Cation by Aromatic Rings

Autor: Jie Jian, Darina Barkhatova, Roel Hammink, Paul Tinnemans, F. Matthias Bickelhaupt, Jordi Poater, Jasmin Mecinović

Publikováno v: Journal of Organic Chemistry, 87, 12, pp. 7875-7883
Journal of Organic Chemistry, 87, 7875-7883
Jian, J, Barkhatova, D, Hammink, R, Tinnemans, P, Bickelhaupt, F M, Poater, J & Mecinović, J 2022, ' Through-Space Stabilization of an Imidazolium Cation by Aromatic Rings ', Journal of Organic Chemistry, vol. 87, no. 12, pp. 7875-7883 . https://doi.org/10.1021/acs.joc.2c00533
Journal of Organic Chemistry, 87(12), 7875-7883. American Chemical Society

Imidazole-based compounds are widely found in natural products, synthetic molecules, and biomolecules. Noncovalent interactions between the imidazole ring and other functional groups play an important role in determining the function of diverse molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa2799ff8700b2bf6a3477a1d3f9303
https://hdl.handle.net/1871.1/b709851a-3294-48cb-a793-ca8a2c75ca20

Probing Polar-π Interactions Between Tetrazoles and Aromatic Rings

Autor: Jie Jian, Roel Hammink, Paul Tinnemans, F. Matthias Bickelhaupt, Jordi Poater, Jasmin Mecinović

Publikováno v: Jian, J, Hammink, R, Tinnemans, P, Bickelhaupt, F M, Poater, J & Mecinović, J 2023, ' Probing Polar-π Interactions Between Tetrazoles and Aromatic Rings ', Chemistry-An Asian Journal, vol. 18, no. 10, e202300192, pp. 1-9 . https://doi.org/10.1002/asia.202300192
Chemistry-An Asian Journal, 18(10):e202300192, 1-9. John Wiley and Sons Ltd
Chemistry, an Asian Journal, 18, 10, pp. 1-9
Chemistry, an Asian Journal, 18, 1-9

The heterocyclic tetrazole, a well-established bioisosteric replacement of carboxylic acid, plays an important role in medicinal chemistry. To deepen the functional understanding of tetrazoles in chemical sciences, it is essential to investigate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbeadd293b04863cac71b2e005f5b13a
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/293011

Probing Noncovalent Interactions in [3,3]Metaparacyclophanes

Autor: Jie Jian, Roel Hammink, Paul Tinnemans, F. Matthias Bickelhaupt, Christine J. McKenzie, Jordi Poater, Jasmin Mecinović

Publikováno v: Journal of Organic Chemistry, 87(9), 6087-6096. American Chemical Society
Journal of Organic Chemistry, 87, 6087-6096
Jian, J, Hammink, R, Tinnemans, P, Bickelhaupt, F M, McKenzie, C J, Poater, J & Mecinović, J 2022, ' Probing noncovalent interactions in [3,3]Metaparacyclophanes ', The Journal of Organic Chemistry, vol. 87, no. 9, pp. 6087-6096 . https://doi.org/10.1021/acs.joc.2c00350
Journal of Organic Chemistry, 87, 9, pp. 6087-6096
Jian, J, Hammink, R, Tinnemans, P, Bickelhaupt, F M, McKenzie, C J, Poater, J & Mecinović, J 2022, ' Probing Noncovalent Interactions in [3,3]Metaparacyclophanes ', Journal of Organic Chemistry, vol. 87, no. 9, pp. 6087-6096 . https://doi.org/10.1021/acs.joc.2c00350

Arene-arene interactions are fundamentally important in molecular recognition. To precisely probe arene-arene interactions in cyclophanes, we designed and synthesized (2,6-phenol)paracyclophanes and (2,6-aniline)paracyclophanes that possess two aroma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6f99fb59d4c07111a0735b9234d508
https://research.vu.nl/en/publications/291dd518-0dc3-4c2c-83fa-b09e179c1873