Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Roel GW. Verhaak"'
Autor:
Wajd N. Al-Holou, Hanxiao Wang, Visweswaran Ravikumar, Sunita Shankar, Morgan Oneka, Ziad Fehmi, Roel GW Verhaak, Hoon Kim, Drew Pratt, Sandra Camelo-Piragua, Corey Speers, Daniel R Wahl, Todd Hollon, Oren Sagher, Jason A Heth, Karin M. Muraszko, Theodore S. Lawrence, Ana C de Carvalho, Tom Mikkelsen, Arvind Rao, Alnawaz Rehemtulla
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 36, Iss , Pp 100872- (2023)
Purpose: Glioblastoma(GBM) is a lethal disease characterized by inevitable recurrence. Here we investigate the molecular pathways mediating resistance, with the goal of identifying novel therapeutic opportunities. Experimental design: We developed a
Externí odkaz:
https://doaj.org/article/a0132180ec4b462dbadc5529f928818b
Autor:
John FP. Bridges, Cheryl Willman, Nikhil Wagle, Roel GW. Verhaak, Jeffrey M. Trent, Jessica C. Tiner, Andrew L. Sussman, Mariana C. Stern, Charité Ricker, Timothy R. Rebbeck, Electra D. Paskett, Shiraz I. Mishra, Qin Ma, Heinz-Josef Lenz, Bethany M. Kwan, Katherine A. Janeway, Ryan C. Fields, Bettina F. Drake, Li Ding, Graham A. Colditz, Elizabeth B. Claus, John D. Carpten, Cindy K. Blair, Melinda Bachini, Norah L. Crossnohere, Anne LR. Schuster
Banner authorship list
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486c2f9d174044a0b36f8d1f06ee97f1
https://doi.org/10.1158/1055-9965.22494715.v1
https://doi.org/10.1158/1055-9965.22494715.v1
Autor:
John FP. Bridges, Cheryl Willman, Nikhil Wagle, Roel GW. Verhaak, Jeffrey M. Trent, Jessica C. Tiner, Andrew L. Sussman, Mariana C. Stern, Charité Ricker, Timothy R. Rebbeck, Electra D. Paskett, Shiraz I. Mishra, Qin Ma, Heinz-Josef Lenz, Bethany M. Kwan, Katherine A. Janeway, Ryan C. Fields, Bettina F. Drake, Li Ding, Graham A. Colditz, Elizabeth B. Claus, John D. Carpten, Cindy K. Blair, Melinda Bachini, Norah L. Crossnohere, Anne LR. Schuster
Background:Engaging diverse populations in cancer genomics research is of critical importance and is a fundamental goal of the NCI Participant Engagement and Cancer Genome Sequencing (PE-CGS) Network. Established as part of the Cancer Moonshot, PE-CG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8490d3be146999ed05fa40f5d41d30
https://doi.org/10.1158/1055-9965.c.6534607.v1
https://doi.org/10.1158/1055-9965.c.6534607.v1
Autor:
Georgette Tanner, Rhiannon Barrow, Martina Finetti, Shoaib Ajaib, Nazia Ahmed, Steven Pollock, Nora Rippaus, Alexander F. Bruns, Khaja Syed, James Poulter, Erica Wilson, Colin Johnson, Frederick S. Varn, Anke Brüning-Richardson, Catherine Hogg, Alastair Droop, Arief Gusnanto, Matthew A. Care, Luisa Cutillo, David Westhead, Susan C. Short, Michael D. Jenkinson, Andrew Brodbelt, Aruna Chakrabarty, Azzam Ismail, Roel GW Verhaak, Lucy F. Stead
Glioblastoma (GBM) brain tumours lackingIDH1mutations (IDHwt) have the worst prognosis of all brain neoplasms. Patients receive surgery and chemoradiotherapy but tumours almost always fatally recur. Using RNAseq data from 107 pairs of pre- and post-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3974987cc1bd108afe32b74c23969c12
https://doi.org/10.1101/2023.02.03.526945
https://doi.org/10.1101/2023.02.03.526945
Autor:
Shoaib Ajaib, Disha Lodha, Steven Pollock, Gemma Hemmings, Martina A. Finetti, Arief Gusnanto, Aruna Chakrabarty, Azzam Ismail, Erica Wilson, Frederick S Varn, Bethany Hunter, Andrew Filby, Asa A. Brockman, David McDonald, Roel GW Verhaak, Rebecca A. Ihrie, Lucy F. Stead
Publikováno v:
Neuro-Oncology.
The biological and clinical impact of neoplastic and immune cell type ratios in the glioblastoma (GBM) tumour microenvironment is being realised. Characterising and quantifying cell types within GBMs at scale will facilitate a better understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc48c1927d253202ef85cf3f0cdc163
https://doi.org/10.1093/neuonc/noad021
https://doi.org/10.1093/neuonc/noad021
Autor:
Frederick S. Varn, Kevin C. Johnson, Jan Martinek, Jason T. Huse, MacLean P. Nasrallah, Pieter Wesseling, Lee A.D. Cooper, Tathiane M. Malta, Taylor E. Wade, Thais S. Sabedot, Daniel Brat, Peter V. Gould, Adelheid Wöehrer, Kenneth Aldape, Azzam Ismail, Santhosh K. Sivajothi, Floris P. Barthel, Hoon Kim, Emre Kocakavuk, Nazia Ahmed, Kieron White, Indrani Datta, Hyo-Eun Moon, Steven Pollock, Christine Goldfarb, Ga-Hyun Lee, Luciano Garofano, Kevin J. Anderson, Djamel Nehar-Belaid, Jill S. Barnholtz-Sloan, Spyridon Bakas, Annette T. Byrne, Fulvio D’Angelo, Hui K. Gan, Mustafa Khasraw, Simona Migliozzi, D. Ryan Ormond, Sun Ha Paek, Erwin G. Van Meir, Annemiek M.E. Walenkamp, Colin Watts, Tobias Weiss, Michael Weller, Karolina Palucka, Lucy F. Stead, Laila M. Poisson, Houtan Noushmehr, Antonio Iavarone, Roel G.W. Verhaak, Kristin D. Alfaro, Samirkumar B. Amin, David M. Ashley, Christoph Bock, Andrew Brodbelt, Ketan R. Bulsara, Ana Valeria Castro, Jennifer M. Connelly, Joseph F. Costello, John F. de Groot, Gaetano Finocchiaro, Pim J. French, Anna Golebiewska, Ann C. Hau, Chibo Hong, Craig Horbinski, Kasthuri S. Kannan, Mathilde CM. Kouwenhoven, Anna Lasorella, Peter S. LaViolette, Keith L. Ligon, Allison K. Lowman, Shwetal Mehta, Hrvoje Miletic, Annette M. Molinaro, Ho Keung Ng, Simone P. Niclou, Johanna M. Niers, Joanna J. Phillips, Raul Rabadan, Ganesh Rao, Guido Reifenberger, Nader Sanai, Susan C. Short, Peter Sillevis Smitt, Andrew E. Sloan, Marion Smits, James M. Snyder, Hiromichi Suzuki, Ghazaleh Tabatabai, Georgette Tanner, William H. Tomaszewski, Michael Wells, Bart A. Westerman, Helen Wheeler, Jichun Xie, W.K. Alfred Yung, Gelareh Zadeh, Junfei Zhao, Roel GW. Verhaak
Publikováno v:
Cell, 185(12), 2184-2199.e16. Cell Press
Cell
Cell, vol 185, iss 12
The GLASS Consortium 2022, ' Glioma progression is shaped by genetic evolution and microenvironment interactions ', Cell, vol. 185, no. 12, pp. 2184-2199.e16 . https://doi.org/10.1016/j.cell.2022.04.038
Cell, 185(12), 2184-2199.e16. CELL PRESS
Cell
Cell, vol 185, iss 12
The GLASS Consortium 2022, ' Glioma progression is shaped by genetic evolution and microenvironment interactions ', Cell, vol. 185, no. 12, pp. 2184-2199.e16 . https://doi.org/10.1016/j.cell.2022.04.038
Cell, 185(12), 2184-2199.e16. CELL PRESS
The factors driving therapy resistance in diffuse glioma remain poorly understood. To identify treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA sequencing data from the temporally separated tumor pairs of 304 adult patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36aa8231290284197e37208bfab4dbba
https://research.vumc.nl/en/publications/312bbb0a-1328-4405-bfbe-cce4f07b8a67
https://research.vumc.nl/en/publications/312bbb0a-1328-4405-bfbe-cce4f07b8a67
Autor:
Wajd N. Al-Holou, Hanxiao Wang, Visweswaran Ravikumar, Morgan Oneka, Roel GW Verhaak, Hoon Kim, Drew Pratt, Sandra Camelo-Piragua, Corey Speers, Daniel R Wahl, Sunita Shankar, Todd Hollon, Oren Sagher, Jason A Heth, Karin M. Muraszko, Theodore S. Lawrence, Ana C de Carvalho, Tom Mikkelsen, Arvind Rao, Alnawaz Rehemtulla
PurposeGlioblastoma (GBM) is a lethal disease characterized by inevitable recurrence. Here we investigate the molecular pathways mediating resistance, with the goal of identifying therapeutic opportunities to target this tumor.Experimental DesignWe d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93c8cd1ffa4a0f30c85cd4f3ba9de731
https://doi.org/10.1101/2021.09.10.459454
https://doi.org/10.1101/2021.09.10.459454