Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Roei D Mazor"'
Autor:
Jonathan Zorea, Yair Motro, Roei D. Mazor, Yifat Koren Carmi, Ziv Shulman, Jamal Mahajna, Jacob Moran-Gilad, Moshe Elkabets
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Ovarian cancer (OC) is known for exhibiting low response rates to immune checkpoint inhibitors that activate T cells. However, immunotherapies that activate B cells have not yet been extensively explored and may be a potential tar
Externí odkaz:
https://doaj.org/article/55a4f78cd4024880a535e0d242aff914
Autor:
Thibaud, Chazal, Francesco, Pegoraro, Gaia, Manari, Alessandra, Bettiol, Valerio, Maniscalco, Elena, Gelain, Frédéric, Charlotte, Roei D, Mazor, Raphaele, Renard-Penna, Zahir, Amoura, Fleur, Cohen-Aubart, Julien, Haroche, Hassan, Izzedine, Augusto, Vaglio
Publikováno v:
Kidney International. 103:177-186
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis that frequently infiltrates the peri-kidney space ("hairy kidney" appearance), kidney pelvis and proximal ureters, leading to obstructive uropathy. Here, we analyzed the clinic
Autor:
Paul Szabolcs, Roei D. Mazor, Dima Yackoubov, Stuart Levy, Patrick Stiff, Andrew Rezvani, Rabi Hanna, John Wagner, Amy Keating, Caroline A. Lindemans, Nicole Karras, Joseph McGuirk, Nelson Hamerschlak, Ivan López-Torija, Guillermo Sanz, David Valcarcel, Mitchell E. Horwitz
Publikováno v:
Transplantation and Cellular Therapy.
Autor:
Ran Weissman, Eli L. Diamond, Julien Haroche, Nir Pillar, Guy Shapira, Benjamin H. Durham, Justin Buthorn, Fleur Cohen, Michelle Ki, Galia Stemer, Gary A. Ulaner, Zahir Amoura, Jean-François Emile, Roei D. Mazor, Noam Shomron, Omar I. Abdel-Wahab, Ofer Shpilberg, Oshrat Hershkovitz-Rokah
Publikováno v:
Cancers, Vol 12, Iss 11, p 3240 (2020)
The pathogenesis of histiocytic neoplasms is driven by mutations activating the MAPK/ERK pathway, but little is known about the transcriptional and post-transcriptional alterations involved in these neoplasms. We analyzed microRNA (miRNA) expression
Externí odkaz:
https://doaj.org/article/9a9d8e8209f9487bbb51247b9d6e5860
Autor:
Justin Buthorn, Noam Shomron, Fleur Cohen, Jean-François Emile, Roei D Mazor, Ofer Shpilberg, Omar Abdel-Wahab, Zahir Amoura, Eli L. Diamond, Ran Weissman, Benjamin H. Durham, Julien Haroche, Oshrat Hershkovitz-Rokah
Publikováno v:
Leukemia
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2021, ⟨10.1038/s41375-021-01472-2⟩
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2021, ⟨10.1038/s41375-021-01472-2⟩
Erdheim–Chester disease (ECD) is characterized by excessive production and accumulation of histiocytes within multiple tissues and organs. ECD patients harbor recurrent mutations of genes associated with the RAS/RAF/MEK/ERK signaling pathway, parti
Autor:
Xin Xin Cao, Benjamin H. Durham, Paul C. Hendrie, Aaron M. Goodman, Jennifer Picarsic, Eric D. Jacobsen, Juvianee Estrada-Veras, Andre Abdo, Michael Girschikofsky, Matthew Collin, Kenneth L. McClain, Mineo Kurokawa, Ronald S. Go, Augusto Vaglio, Mark L. Heaney, Kazuhiro Toyama, Lorenzo Dagna, Julien Haroche, Oshrat Hershkovitz-Rokah, Eli L. Diamond, Ofer Shpilberg, Roei D Mazor, Filip Janku, Fleur Cohen-Aubart, Gaurav Goyal
Publikováno v:
Blood. 135:1929-1945
Erdheim-Chester disease (ECD) is a rare histiocytosis that was recently recognized as a neoplastic disorder owing to the discovery of recurrent activating MAPK (RAS-RAF-MEK-ERK) pathway mutations. Typical findings of ECD include central diabetes insi
Autor:
Ronen Gabizon, Eilat Shinar, Ron Diskin, Lihee Moss, Roei D Mazor, Sigal Leviatan, Shelley Klompus, Nachum Nathan, Gur Yaari, Hadas Cohen Dvashi, Liat Stoler-Barak, Sharon Kagan Ben Tikva, Anastasia Godneva, Ziv Shulman, Iris N. Kalka, Thomas Vogl, Eran Segal, Nir London, Adina Weinberger, Ayelet Peres
Publikováno v:
Science Immunology
The spillover of animal coronaviruses (aCoVs) to humans has caused SARS, MERS, and COVID-19. While antibody responses displaying cross-reactivity between SARS-CoV-2 and seasonal/common cold human coronaviruses (hCoVs) have been reported, potential cr
Autor:
Ran Weissman, Omar Abdel-Wahab, Ofer Shpilberg, Shirley Shapira, Judith Luckman, Eli L. Diamond, Roei D Mazor, Liran Domachevsky, Oshrat Hershkovitz-Rokah, David Groshar
Publikováno v:
Neuro-oncology Advances
Background Erdheim–Chester disease (ECD), a rare inflammatory myeloid neoplasm, is known to be fundamentally reliant on the constitutive activation of the MAPK signaling pathway in the majority of patients. Consequently, inhibition of the V600E-mut
Autor:
Nir Pillar, Galia Stemer, Eli L. Diamond, Benjamin H. Durham, Ofer Shpilberg, Omar Abdel-Wahab, Zahir Amoura, Ran Weissman, Jean-François Emile, Julien Haroche, Fleur Cohen, Justin Buthorn, Michelle Ki, Gary A. Ulaner, Oshrat Hershkovitz-Rokah, Guy Shapira, Noam Shomron, Roei D Mazor
Publikováno v:
Cancers
Cancers, MDPI, 2020, 12 (11), pp.1-20. ⟨10.3390/cancers12113240⟩
Volume 12
Issue 11
Cancers, Vol 12, Iss 3240, p 3240 (2020)
Cancers, MDPI, 2020, 12 (11), pp.1-20. ⟨10.3390/cancers12113240⟩
Volume 12
Issue 11
Cancers, Vol 12, Iss 3240, p 3240 (2020)
The pathogenesis of histiocytic neoplasms is driven by mutations activating the MAPK/ERK pathway, but little is known about the transcriptional and post-transcriptional alterations involved in these neoplasms. We analyzed microRNA (miRNA) expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2377320e7004ec40620f441afabf4d
https://hal.archives-ouvertes.fr/hal-03032298
https://hal.archives-ouvertes.fr/hal-03032298
Autor:
Irina Zaretsky, Alexander D. Gitlin, Liat Stoler-Barak, Adi Biram, Sara W. Feigelson, Ziv Shulman, Roei D Mazor, Britta Engelhardt, Ofir Atrakchi
Publikováno v:
The Journal of Experimental Medicine
Zaretsky, Irina; Atrakchi, Ofir; Mazor, Roei D; Stoler-Barak, Liat; Biram, Adi; Feigelson, Sara W; Gitlin, Alexander D; Engelhardt, Britta; Shulman, Ziv (2017). ICAMs support B cell interactions with T follicular helper cells and promote clonal selection. The Journal of experimental medicine, 214(11), pp. 3435-3448. Rockefeller Univ. Press 10.1084/jem.20171129
Zaretsky, Irina; Atrakchi, Ofir; Mazor, Roei D; Stoler-Barak, Liat; Biram, Adi; Feigelson, Sara W; Gitlin, Alexander D; Engelhardt, Britta; Shulman, Ziv (2017). ICAMs support B cell interactions with T follicular helper cells and promote clonal selection. The Journal of experimental medicine, 214(11), pp. 3435-3448. Rockefeller Univ. Press 10.1084/jem.20171129
The molecular mechanism governing affinity-based B cell selection for germinal center colonization is unclear. Zaretsky et al. show that B cell ICAMs promote efficient B cell selection for clonal expansion by supporting sustained interactions with T