Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rodsy Modhurima"'
Autor:
Han B. Lee, Soaleha Shams, Viet Ha Dang Thi, Grace E. Boyum, Rodsy Modhurima, Emma M. Hall, Izzabella K. Green, Elizabeth M. Cervantes, Fernando E. Miguez, Karl J. Clark
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract The vertebrate stress response (SR) is mediated by the hypothalamic–pituitary–adrenal (HPA) axis and contributes to generating context appropriate physiological and behavioral changes. Although the HPA axis plays vital roles both in stre
Externí odkaz:
https://doaj.org/article/2098392ad32f4515bf10d2115e196394
Autor:
Maurizio Fazio, Ellen van Rooijen, Michelle Dang, Glenn van de Hoek, Julien Ablain, Jeffrey K Mito, Song Yang, Andrew Thomas, Jonathan Michael, Tania Fabo, Rodsy Modhurima, Patrizia Pessina, Charles K Kaufman, Yi Zhou, Richard M White, Leonard I Zon
Publikováno v:
eLife, Vol 10 (2021)
Recent genomic and scRNA-seq analyses of melanoma demonstrated a lack of recurrent genetic drivers of metastasis, while identifying common transcriptional states correlating with invasion or drug resistance. To test whether transcriptional adaptation
Externí odkaz:
https://doaj.org/article/b2a52bd0b3874cc18579f387a8732b1a
Autor:
Megan L. Insco, Brian J. Abraham, Sara J. Dubbury, Ines H. Kaltheuner, Sofia Dust, Constance Wu, Kevin Y. Chen, David Liu, Stanislav Bellaousov, Anna M. Cox, Benjamin J. E. Martin, Tongwu Zhang, Calvin G. Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E. Esgdaille, Telmo Henriques, Kevin M. Brown, Stephen J. Chanock, Matthias Geyer, Karen Adelman, Phillip A. Sharp, Richard A. Young, Paul L. Boutz, Leonard I. Zon
Publikováno v:
Science
RNA surveillance pathways detect and degrade defective transcripts to ensure RNA fidelity. We found that disrupted nuclear RNA surveillance is oncogenic. Cyclin-dependent kinase 13 ( CDK13 ) is mutated in melanoma, and patient-mutated CDK13 accelerat
Autor:
Han B. Lee, Viet Ha Dang Thi, Grace E. Boyum, Rodsy Modhurima, Emma M. Hall, Izzabella K. Green, Elizabeth Cervantes, Soaleha Shams, Karl J. Clark
The hypothalamic-pituitary-adrenal (HPA) axis and its effector molecules—glucocorticoids—modulate diverse aspects of physiology in vertebrates ranging from metabolism to immune function, behavior, and circadian cycle. While the glucocorticoid rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a0c530eb4b543f8f0e4d14ce7121836
https://doi.org/10.1101/2022.05.14.491921
https://doi.org/10.1101/2022.05.14.491921
Autor:
Jeffrey K. Mito, Rodsy Modhurima, Leonard I. Zon, Song Yang, Erika Weiskopf, Ellen van Rooijen, Maurizio Fazio
Publikováno v:
Pigment Cell Melanoma Res
A progressive increase in copy number variation (CNV) characterizes the natural history of cutaneous melanoma progression toward later disease stages, but our understanding of genetic drivers underlying chromosomal arm-level CNVs remains limited. To
Autor:
Marlies P. Rossmann, Maurizio Fazio, Dorothee Bornhorst, Michael J. Fairchild, Avik Choudhuri, Leonard I. Zon, Jodi Weiss, Shannon Freyer, Audrey Sporrij, Iris T. Chan, Rodsy Modhurima, Julien Ablain, Meera Prasad, Hadley M Moreau, Margaret C. Weber, Meredith E. Stanhope, Elliott J. Hagedorn, Jason D. Boisvert, Julia Barbano, Serine Avagyan, Mackenzie Smith, Alicia M. McConnell, Rebecca J. Freeman
Publikováno v:
Cell. 184(7)
Many scientists spend unnecessary time reformatting papers to submit them to different journals. We propose a uniform submission format that we hope journals will include in their options for submission. Widespread adoption of this uniform submission
Autor:
Richard M. White, Song Yang, Glenn van de Hoek, Andrew Thomas, Charles K. Kaufman, Rodsy Modhurima, Leonard I. Zon, Ellen van Rooijen, Yi Zhou, Patrizia Pessina, Maurizio Fazio, Jonathan Michael, Tania Fabo, Jeffrey K. Mito, Julien Ablain, Michelle Dang
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Recent genomic and scRNA-seq analyses of melanoma demonstrated a lack of recurrent genetic drivers of metastasis, while identifying common transcriptional states correlating with invasion or drug resistance. To test whether transcriptional adaptation
Autor:
Charles K. Kaufman, Julien Ablain, Michelle Dang, Richard M. White, Maurizio Fazio, Ellen van Rooijen, Jonathan Michael, Tania Fabo, Jeffrey K. Mito, Yi Zhou, Andrew Thomas, Patrizia Pessina, Song Yang, Glenn van de Hoek, Rodsy Modhurima, Leonard I. Zon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc7beb98fc71816eacce647852e80843
https://doi.org/10.7554/elife.64370.sa2
https://doi.org/10.7554/elife.64370.sa2
Autor:
Rida Ansari, Lior Appelbaum, W. Philip Bartel, Carla Denise Bonan, Caroline H. Brennan, Edward A. Burton, Michael J. Carvan III, Karl J. Clark, Rosane Souza Da Silva, Konstantin A. Demin, Flavia De Santis, Vincenzo Di Donato, Elena Dreosti, Marc Ekker, Amanda Facciol, Gert Flik, Robert T. Gerlai, Marnix Gorissen, Fabrizio Grieco, Su Guo, Amanda A. Heeren, Dennis M. Higgs, Ellen J. Hoffman, Kerstin Howe, Khang Hua, Arnim Jenett, Allan V. Kalueff, Konstantinos Kalyviotis, Justin W. Kenney, Anton M. Lakstygal, Han B. Lee, Emmanuel Marquez-Legorreta, Noam Miller, Rodsy Modhurima, Stephan C.F. Neuhauss, Lucas P.J.J. Noldus, William HJ. Norton, Periklis Pantazis, David M. Parichy, Marielle Piber, John H. Postlethwait, David Pritchett, Hanyu Qin, Jason Rihel, Domino K. Schlegel, Ethan K. Scott, Alexander Stankiewicz, S.J. Stednitz, Ruud A.J. Tegelenbosch, Javier Terriente, Steven Tran, Benjamin Tsang, Sachiko Tsuda, Ruud van den Bos, Victor S. Van Laar, Monica Ryff Moreira Roca Vianna, P. Washbourne, Svante Winberg, Jiale Xu, David Zada, Irina V. Zhdanova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac2d8bf5edd950288cc2f43ee814830f
https://doi.org/10.1016/b978-0-12-817528-6.01002-0
https://doi.org/10.1016/b978-0-12-817528-6.01002-0
Autor:
Julien Ablain, Shixin Yang, Maurizio Fazio, Charles K. Kaufman, van Rooijen E, Rodsy Modhurima, Jeffrey K. Mito, Jonathan Michael, Andrew Thomas, Leonard I. Zon, Michelle Dang, Yunli Zhou, Richard M. White, Tania Fabo, Patrizia Pessina, van de Hoek G
Recent genomic and scRNA-seq analyses of melanoma identified common transcriptional states correlating with invasion or drug resistance, but failed to find recurrent drivers of metastasis. To test whether transcriptional adaptation can drive melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2143569dabd66b23b254f00b69e0b271
https://doi.org/10.1101/2020.11.01.364406
https://doi.org/10.1101/2020.11.01.364406