Inhibiting N-glycan processing increases the antibody binding affinity and effector function of human natural killer cells.

Autor: Rodriguez Benavente MC; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA., Hughes HB; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA., Kremer PG; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA., Subedi GP; Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa, USA., Barb AW; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.; Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa, USA.; Department of Chemistry, University of Georgia, Athens, Georgia, USA.; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.

Publikováno v: Immunology [Immunology] 2023 Oct; Vol. 170 (2), pp. 202-213. Date of Electronic Publication: 2023 May 22.

The antibody-binding Fc gamma receptor IIIa / CD16a is N-glycosylated with high occupancy at all five sites.

Autor: Lampros EA; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA., Kremer PG; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA., Aguilar Díaz de León JS; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA., Roberts ET; Department of Chemistry, University of Georgia, Athens, GA, USA., Rodriguez Benavente MC; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA., Amster IJ; Department of Chemistry, University of Georgia, Athens, GA, USA.; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, USA., Barb AW; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA.; Department of Chemistry, University of Georgia, Athens, GA, USA.; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.

Publikováno v: Current research in immunology [Curr Res Immunol] 2022 Jun 09; Vol. 3, pp. 128-135. Date of Electronic Publication: 2022 Jun 09 (Print Publication: 2022).

Fc γ receptor IIIa/CD16a processing correlates with the expression of glycan-related genes in human natural killer cells.

Autor: Patel KR; Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa, USA., Rodriguez Benavente MC; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA., Lorenz WW; Georgia Genomics and Bioinformatics Core and Institute of Bioinformatics, University of Georgia, Athens, Georgia, USA., Mace EM; Department of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA., Barb AW; Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa, USA; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA. Electronic address: abarb@uga.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100183. Date of Electronic Publication: 2020 Dec 16.

Positional Scanning MUC1 Glycopeptide Library Reveals the Importance of PDTR Epitope Glycosylation for Lectin Binding.

Autor: Singh Y; From the Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science , Florida Atlantic University , 777 Glades Road , Boca Raton , Florida 33431 , United States., Rodriguez Benavente MC; From the Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science , Florida Atlantic University , 777 Glades Road , Boca Raton , Florida 33431 , United States., Al-Huniti MH; From the Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science , Florida Atlantic University , 777 Glades Road , Boca Raton , Florida 33431 , United States., Beckwith D; From the Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science , Florida Atlantic University , 777 Glades Road , Boca Raton , Florida 33431 , United States., Ayyalasomayajula R; From the Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science , Florida Atlantic University , 777 Glades Road , Boca Raton , Florida 33431 , United States., Patino E; From the Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science , Florida Atlantic University , 777 Glades Road , Boca Raton , Florida 33431 , United States., Miranda WS; From the Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science , Florida Atlantic University , 777 Glades Road , Boca Raton , Florida 33431 , United States., Wade A; From the Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science , Florida Atlantic University , 777 Glades Road , Boca Raton , Florida 33431 , United States., Cudic M; From the Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science , Florida Atlantic University , 777 Glades Road , Boca Raton , Florida 33431 , United States.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2020 Feb 07; Vol. 85 (3), pp. 1434-1445. Date of Electronic Publication: 2019 Dec 18.

Glycosylation pathways at the ocular surface.

Autor: Rodriguez Benavente MC; Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, U.S.A., Argüeso P; Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, U.S.A. pablo_argueso@meei.harvard.edu.

Publikováno v: Biochemical Society transactions [Biochem Soc Trans] 2018 Apr 17; Vol. 46 (2), pp. 343-350. Date of Electronic Publication: 2018 Mar 09.