Výsledky vyhledávání - "Rodrigues, Felipe A. R."

Cytotoxic Evaluation of Substituted Benzaldehydes

Autor: Rodrigues, Felipe A. R., Oliveira, Augusto C. A., Cavalcanti, Bruno C., Costa, Marcília P., Pessoa, Claudia, Souza, Marcus V. N. de, Pinheiro, Alessandra C.

Publikováno v: Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC

A series of fifty-four commercial aldehydes have been synthesized and evaluated for their activity against peripheral blood mononuclear cells (PBMC) and four human cancer cell lines, exhibiting potent citotoxicity (IC50 ranging from 0.36 to 4.75 μg/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8485412600e6470984422704f1c2884c

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Biological Evaluation of Pyrazinamide Derivatives as An Anticancer Class

Autor: Rodrigues, Felipe A. R., Bomfim, Igor Da S., Cavalcanti, Bruno C., Pessoa, Claudia Do Ó, Pinheiro, Alessandra C., Lima, Camilo H. S., De Souza, Marcus V. N.

A series of fifty one pyrazinyl derivatives have been synthesized and evaluated for their activity against four cancer cell lines, exhibiting good citotoxicity (IC50 ranging from 1.1 to 5.6μg/mL). The structure-activity relationship (SAR) analysis i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d63dcd72b549233d455bc9c55afa34e8

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Arylamino-nor-b-lapachone derivative-induced apoptosis in human prostate cancer cells: involvement of NAD(P)H :quinone oxidoreductase (NQO1)

Autor: Cavalcanti, Bruno C., Magalhães, Hemerson I. F., Rodrigues, Felipe A. R., Moraes Filho, Manoel Odorico de, Pessoa, Cláudia

Publikováno v: Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC

b-lapachone, a DNA repair inhibitor, has been recognized as important prototype with activity against cancer cells devoided of cytotoxicity in non-tumor cells. NQO1 is a reductive enzyme that is important for the activation of many bioreductive quino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::97c01c8b59f7cca64a931798efe1190c
http://www.repositorio.ufc.br/handle/riufc/7232

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Genetic toxicology evaluation of essential oil of Alpinia zerumbet and its chemoprotective effects against H 2 O 2 -induced DNA damage in cultured human leukocytes

Autor: Cavalcanti, Bruno C., Ferreira, José R. O., Cabral, Igor O., Magalhães, Hemerson I. F., Oliveira, Cecília C. de, Rodrigues, Felipe A. R., Rocha, Danilo D., Barros, Francisco W. A., Silva, Cecília R. da, Nobre Júnior, Hélio Vitoriano, Canuto, Kirley M., Silveira, Edilberto R., Pessoa, Cláudia, Moraes Filho, Manoel Odorico de

Publikováno v: Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC

Essential oil (EO) of Alpinia zerumbet leaves, at non-toxic concentrations (50–300 l g/mL), did not induce genotoxicity in human leukocytes. However, at the highest concentration (500 l g/mL) tested caused a reduction in cell proliferation and viab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::0a17d27f5b07a1849e92d4952b3947d8
http://www.repositorio.ufc.br/handle/riufc/5542

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In vitro studies on Bothrops venoms cytotoxic effect on tumor cells

Autor: Jorge, Roberta J. B., Martins, Alice M. C., Morais, Isabel C. O., Ximenes, Rafael M., Rodrigues, Felipe A. R., Soares, Bruno M., Evangelista, Janaina S. A. M., Toyama, Marcos H. [UNESP], Martins, Aline M. A., Moraes Filho, Manoel O., Monteiro, Helena S. A.

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2022-04-29T02:17:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-12-29 Background: Animal venoms are complex mixtures of proteins and non proteins components with several biological activities. Snake venoms repre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::7a4ccc08866bb1ef2310199298305400

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