Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Rodrigo Said Razo-Hernández"'
Autor:
Estefany Bello-Vargas, Mario Alberto Leyva-Peralta, Zeferino Gómez-Sandoval, Mario Ordóñez, Rodrigo Said Razo-Hernández
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1688 (2023)
Among the biological targets extensively investigated to improve inflammation and chronic inflammatory conditions, cyclooxygenase enzymes (COXs) occupy a prominent position. The inhibition of these enzymes, essential for mitigating inflammatory proce
Externí odkaz:
https://doaj.org/article/d111d1ee1d904dd4beb43f06eebc6991
Autor:
Diana López-López, Rodrigo Said Razo-Hernández, César Millán-Pacheco, Mario Alberto Leyva-Peralta, Omar Aristeo Peña-Morán, Jessica Nayelli Sánchez-Carranza, Verónica Rodríguez-López
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1647 (2023)
Cervical cancer is a malignant neoplastic disease, mainly associated to HPV infection, with high mortality rates. Among natural products, iridoids have shown different biological activities, including cytotoxic and antitumor effects, in different can
Externí odkaz:
https://doaj.org/article/893e575b378f4e9bb29c4043f4d634e8
Autor:
Isis A. Y. Ventura-Salazar, Francisco J. Palacios-Can, Leticia González-Maya, Jessica Nayelli Sánchez-Carranza, Mayra Antunez-Mojica, Rodrigo Said Razo-Hernández, Laura Alvarez
Publikováno v:
Molecules, Vol 28, Iss 14, p 5486 (2023)
In this work, we carried out the design and synthesis of new chimeric compounds from the natural cytotoxic chalcone 2′,4′-dihydroxychalcone (2′,4′-DHC, A) in combination with cinnamic acids. For this purpose, a descriptive and predictive quan
Externí odkaz:
https://doaj.org/article/3a6b09bebb9c4996bdcf6e428f159cd5
Autor:
Abimelek Cortes-Pacheco, María Adelina Jiménez-Arellanes, Francisco José Palacios-Can, José Antonio Valcarcel-Gamiño, Rodrigo Said Razo-Hernández, María del Carmen Juárez-Vázquez, Adolfo López-Torres, Oscar Abelardo Ramírez-Marroquín
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1277-1287 (2020)
Bisphosphonic acids (or bisphosphonates) have been successfully used in the clinic treatment of bone diseases for over decades. Additionally, the antiinflammatory activity of these compounds has been gaining attention. In our previous work, we synthe
Externí odkaz:
https://doaj.org/article/7f2c12e9a4154e5391106e51fb739bb1
Autor:
Hiram Hernández-López, Socorro Leyva-Ramos, Cesar Fernando Azael Gómez-Durán, Alberto Pedraza-Alvarez, Irving Rubén Rodríguez-Gutiérrez, Mario Alberto Leyva-Peralta, Rodrigo Said Razo-Hernández
Publikováno v:
ACS Omega, Vol 5, Iss 23, Pp 14061-14068 (2020)
Externí odkaz:
https://doaj.org/article/9922ce9afd9745b9a9f67293957da96e
Autor:
Francisco José Palacios-Can, Jesús Silva-Sánchez, Ismael León-Rivera, Hugo Tlahuext, Nina Pastor, Rodrigo Said Razo-Hernández
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 250 (2023)
As the rate of discovery of new antibacterial compounds for multidrug-resistant bacteria is declining, there is an urge for the search for molecules that could revert this tendency. Acinetobacter baumannii has emerged as a highly virulent Gram-negati
Externí odkaz:
https://doaj.org/article/6314eddc85264a739061d3a06b9ffb1b
Autor:
Alberto Marbán-González, Armando Hernández-Mendoza, Mario Ordóñez, Rodrigo Said Razo-Hernández, José Luis Viveros-Ceballos
Publikováno v:
Molecules, Vol 26, Iss 24, p 7606 (2021)
Chitinases represent an alternative therapeutic target for opportunistic invasive mycosis since they are necessary for fungal cell wall remodeling. This study presents the design of new chitinase inhibitors from a known hydrolysis intermediate. First
Externí odkaz:
https://doaj.org/article/e8d1f8f67772479c8d3e8a4d86243dd5
Autor:
Rodrigo Said Razo-Hernández, José Luis Viveros-Ceballos, Josué Vazquez-Chavez, Mario Ordóñez, Marcos Hernández-Rodríguez, Alberto Marbán-González, Gaspar Maravilla-Moreno
Publikováno v:
The Journal of Organic Chemistry. 86:16361-16368
Kinetically controlled cyclocondensation of stereoisomeric and ring-chain tautomeric mixture of (±)-hydroxylactone 1 and 0.5 equiv of (R)-phenylglycinol provided tricyclic oxazoloisoindolone lactam (3R,5aS,9aR,9bS)-2a, a versatile intermediate for f
Autor:
Rodrigo Said Razo-Hernández, Eusebio Juaristi, Edmundo Castillo, Nina Pastor, Jaime Escalante, Marina A. Ortega-Rojas
Publikováno v:
European Journal of Organic Chemistry. 2021:4790-4802
Autor:
Jaime, Cardoso-Ortiz, Socorro, Leyva-Ramos, Kim M, Baines, Cesar Fernando Azael, Gómez-Durán, Hiram, Hernández-López, Francisco José, Palacios-Can, José Antonio, Valcarcel-Gamiño, Mario Alberto, Leyva-Peralta, Rodrigo Said, Razo-Hernández
Publikováno v:
Journal of molecular structure. 1274
This study was designed to synthesize hybridizing molecules from ciprofloxacin and norfloxacin by enhancing their biological activity with tetrazoles. The synthesized compounds were investigated in the interaction with the target enzyme of fluoroquin