Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Rodrigo Said"'
Autor:
Estefany Bello-Vargas, Mario Alberto Leyva-Peralta, Zeferino Gómez-Sandoval, Mario Ordóñez, Rodrigo Said Razo-Hernández
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1688 (2023)
Among the biological targets extensively investigated to improve inflammation and chronic inflammatory conditions, cyclooxygenase enzymes (COXs) occupy a prominent position. The inhibition of these enzymes, essential for mitigating inflammatory proce
Externí odkaz:
https://doaj.org/article/d111d1ee1d904dd4beb43f06eebc6991
Autor:
Diana López-López, Rodrigo Said Razo-Hernández, César Millán-Pacheco, Mario Alberto Leyva-Peralta, Omar Aristeo Peña-Morán, Jessica Nayelli Sánchez-Carranza, Verónica Rodríguez-López
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1647 (2023)
Cervical cancer is a malignant neoplastic disease, mainly associated to HPV infection, with high mortality rates. Among natural products, iridoids have shown different biological activities, including cytotoxic and antitumor effects, in different can
Externí odkaz:
https://doaj.org/article/893e575b378f4e9bb29c4043f4d634e8
Autor:
Isis A. Y. Ventura-Salazar, Francisco J. Palacios-Can, Leticia González-Maya, Jessica Nayelli Sánchez-Carranza, Mayra Antunez-Mojica, Rodrigo Said Razo-Hernández, Laura Alvarez
Publikováno v:
Molecules, Vol 28, Iss 14, p 5486 (2023)
In this work, we carried out the design and synthesis of new chimeric compounds from the natural cytotoxic chalcone 2′,4′-dihydroxychalcone (2′,4′-DHC, A) in combination with cinnamic acids. For this purpose, a descriptive and predictive quan
Externí odkaz:
https://doaj.org/article/3a6b09bebb9c4996bdcf6e428f159cd5
Autor:
Matt D. T. Hitchings, Otavio T. Ranzani, Murilo Dorion, Tatiana Lang D’Agostini, Regiane Cardoso de Paula, Olivia Ferreira Pereira de Paula, Edlaine Faria de Moura Villela, Mario Sergio Scaramuzzini Torres, Silvano Barbosa de Oliveira, Wade Schulz, Maria Almiron, Rodrigo Said, Roberto Dias de Oliveira, Patricia Vieira Silva, Wildo Navegantes de Araújo, Jean Carlo Gorinchteyn, Jason R. Andrews, Derek A. T. Cummings, Albert I. Ko, Julio Croda
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Here, the authors investigate the effectiveness of the Oxford-AstraZeneca (ChAdOx1) vaccine during extensive Gamma variant SARS-CoV-2 circulation in São Paulo state, Brazil, and find that a two-dose regime is more effective than one dose against mil
Externí odkaz:
https://doaj.org/article/25345dc94b034a88babc4fab31866050
Autor:
Francisco José Palacios-Can, Jesús Silva-Sánchez, Ismael León-Rivera, Hugo Tlahuext, Nina Pastor, Rodrigo Said Razo-Hernández
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 250 (2023)
As the rate of discovery of new antibacterial compounds for multidrug-resistant bacteria is declining, there is an urge for the search for molecules that could revert this tendency. Acinetobacter baumannii has emerged as a highly virulent Gram-negati
Externí odkaz:
https://doaj.org/article/6314eddc85264a739061d3a06b9ffb1b
Autor:
Abimelek Cortes-Pacheco, María Adelina Jiménez-Arellanes, Francisco José Palacios-Can, José Antonio Valcarcel-Gamiño, Rodrigo Said Razo-Hernández, María del Carmen Juárez-Vázquez, Adolfo López-Torres, Oscar Abelardo Ramírez-Marroquín
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1277-1287 (2020)
Bisphosphonic acids (or bisphosphonates) have been successfully used in the clinic treatment of bone diseases for over decades. Additionally, the antiinflammatory activity of these compounds has been gaining attention. In our previous work, we synthe
Externí odkaz:
https://doaj.org/article/7f2c12e9a4154e5391106e51fb739bb1
Autor:
Hiram Hernández-López, Socorro Leyva-Ramos, Cesar Fernando Azael Gómez-Durán, Alberto Pedraza-Alvarez, Irving Rubén Rodríguez-Gutiérrez, Mario Alberto Leyva-Peralta, Rodrigo Said Razo-Hernández
Publikováno v:
ACS Omega, Vol 5, Iss 23, Pp 14061-14068 (2020)
Externí odkaz:
https://doaj.org/article/9922ce9afd9745b9a9f67293957da96e
Autor:
Matt D.T. Hitchings, Otavio T. Ranzani, Mario Sergio Scaramuzzini Torres, Silvano Barbosa de Oliveira, Maria Almiron, Rodrigo Said, Ryan Borg, Wade L. Schulz, Roberto Dias de Oliveira, Patricia Vieira da Silva, Daniel Barros de Castro, Vanderson de Souza Sampaio, Bernardino Cláudio de Albuquerque, Tatyana Costa Amorim Ramos, Shadia Hussami Hauache Fraxe, Cristiano Fernandes da Costa, Felipe Gomes Naveca, Andre M. Siqueira, Wildo Navegantes de Araújo, Jason R. Andrews, Derek A.T. Cummings, Albert I. Ko, Julio Croda
Publikováno v:
The Lancet Regional Health. Americas, Vol 1, Iss , Pp 100025- (2021)
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant, Gamma, emerged in the city of Manaus in late 2020 during a large resurgence of coronavirus disease (COVID-19), and has spread throughout Brazil. The effectiveness of va
Externí odkaz:
https://doaj.org/article/dd7204efd65940959cc4d0ed2aeccf21
Autor:
Alberto Marbán-González, Armando Hernández-Mendoza, Mario Ordóñez, Rodrigo Said Razo-Hernández, José Luis Viveros-Ceballos
Publikováno v:
Molecules, Vol 26, Iss 24, p 7606 (2021)
Chitinases represent an alternative therapeutic target for opportunistic invasive mycosis since they are necessary for fungal cell wall remodeling. This study presents the design of new chitinase inhibitors from a known hydrolysis intermediate. First
Externí odkaz:
https://doaj.org/article/e8d1f8f67772479c8d3e8a4d86243dd5
Autor:
Jessica Nayelli Sanchez-Carranza, Leticia González-Maya, Rodrigo Said Razo-Hernández, Enrique Salas-Vidal, Ninfa Yaret Nolasco-Quintana, Aldo F. Clemente-Soto, Lucero García-Arizmendi, Mariana Sánchez-Ramos, Silvia Marquina, Laura Alvarez
Publikováno v:
Pharmaceutics, Vol 11, Iss 10, p 512 (2019)
Multidrug resistance (MDR) has become a major obstacle in the treatment of cancer, and is associated with mechanisms such as increased drug outflow, reduction of apoptosis, and/or altered drug metabolism. These problems can be mitigated by the coadmi
Externí odkaz:
https://doaj.org/article/82ceffc9034d465da36b789c5ddfa0de