Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Rodrigo Portes Ureshino"'
Autor:
Tiago Nicoliche, Cynthia Silva Bartolomeo, Robertha Mariana Rodrigues Lemes, Gabriela Cruz Pereira, Tamires Alves Nunes, Rafaela Brito Oliveira, Arthur Luiz Miranda Nicastro, Érica Novaes Soares, Brenno Fernandes da Cunha Lima, Beatriz Moreira Rodrigues, Juliana Terzi Maricato, Liria Hiromi Okuda, Mirela Inês de Sairre, Carla Máximo Prado, Rodrigo Portes Ureshino, Roberta Sessa Stilhano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract COVID-19, caused by SARS-CoV-2, affects neuronal cells, causing several symptoms such as memory loss, anosmia and brain inflammation. Curcuminoids (Me08 e Me23) and curcumin (CUR) are derived from Curcuma Longa extract (EXT). Many therapeuti
Externí odkaz:
https://doaj.org/article/bbe8f6f09dce40cf953471393c987929
Autor:
Érica Novaes Soares, Ana Carla dos Santos Costa, Gabriel de Jesus Ferrolho, Rodrigo Portes Ureshino, Bruk Getachew, Silvia Lima Costa, Victor Diogenes Amaral da Silva, Yousef Tizabi
Publikováno v:
Cells, Vol 13, Iss 6, p 474 (2024)
Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by resting tremor, bradykinesia, rigidity, and postural instability that also includes non-motor symptoms such as mood dysregulation. Dopamine (DA) is the primary neu
Externí odkaz:
https://doaj.org/article/1b2d12e45f5f4e76b51ef1e49c31f1ad
Autor:
Cássia Arruda de Souza Pereira, Natalia de Castro Medaglia, Rodrigo Portes Ureshino, Claudia Bincoletto, Manuela Antonioli, Gian Maria Fimia, Mauro Piacentini, Gustavo José da Silva Pereira, Adolfo Garcia Erustes, Soraya Soubhi Smaili
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5593 (2023)
Huntington’s disease (HD) is a progressive neurodegenerative disease characterized by mutations in the huntingtin gene (mHtt), causing an unstable repeat of the CAG trinucleotide, leading to abnormal long repeats of polyglutamine (poly-Q) in the N-
Externí odkaz:
https://doaj.org/article/ea9be9a1522b41b58781fda1541b26f1
Autor:
Robertha Mariana Rodrigues Lemes, Angelica Jardim Costa, Cynthia Silva Bartolomeo, Taysa Bervian Bassani, Michelle Sayuri Nishino, Gustavo Jose da Silva Pereira, Soraya Soubhi Smaili, Rui Monteiro de Barros Maciel, Carla Torres Braconi, Edgar Ferreira da Cruz, Ana Lopez Ramirez, Juliana Terzi Maricatto, Luiz Mario Ramos Janini, Carla Máximo Prado, Roberta Sessa Stilhano, Rodrigo Portes Ureshino
Publikováno v:
Physiological Reports, Vol 9, Iss 2, Pp n/a-n/a (2021)
Abstract The COVID‐19 has originated from Wuhan, China, in December 2019 and has been affecting the public health system, society, and economy in an unheard‐of manner. There is no specific treatment or vaccine available for COVID‐19. Previous d
Externí odkaz:
https://doaj.org/article/d42a52c6b6f548f6a806c498751adc62
Autor:
Mari Luminosa Muler, Fernanda Antunes, Gabriel Cicolin Guarache, Rafaela Brito Oliveira, Rodrigo Portes Ureshino, Claudia Bincoletto, Gustavo José da Silva Pereira, Soraya Soubhi Smaili
Publikováno v:
Einstein (São Paulo), Vol 18 (2020)
ABSTRACT Objective To investigate if ICI 182,780 (fulvestrant), a selective estrogen receptor alpha/beta (ERα/ERβ) antagonist, and G-1, a selective G-protein-coupled receptor (GPER) agonist, can potentially induce autophagy in breast cancer cell li
Externí odkaz:
https://doaj.org/article/9f80c369e15d459fa3994de9a1e13075
Autor:
Fernanda Antunes, Adolfo Garcia Erustes, Angélica Jardim Costa, Ana Carolina Nascimento, Claudia Bincoletto, Rodrigo Portes Ureshino, Gustavo José Silva Pereira, Soraya Soubhi Smaili
Publikováno v:
Clinics, Vol 73, Iss suppl 1 (2018)
Cancer is a leading cause of death worldwide, and its incidence is continually increasing. Although anticancer therapy has improved significantly, it still has limited efficacy for tumor eradication and is highly toxic to healthy cells. Thus, novel t
Externí odkaz:
https://doaj.org/article/e00c0d840d7d40c183b74012255cbbcd
Autor:
Angelica Jardim Costa, Adolfo Garcia Erustes, Rita Sinigaglia, Carlos Eduardo Neves Girardi, Gustavo José da Silva Pereira, Rodrigo Portes Ureshino, Soraya Soubhi Smaili
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 135 (2021)
The pharmacological modulation of autophagy is considered a promising neuroprotective strategy. While it has been postulated that lithium regulates this cellular process, the age-related effects have not been fully elucidated. Here, we evaluated lith
Externí odkaz:
https://doaj.org/article/8f43aee2f30946d09fa573ccd63c37dc
Autor:
Ana Cristina Breithaupt-Faloppa, Cristiano de Jesus Correia, Carla Máximo Prado, Roberta Sessa Stilhano, Rodrigo Portes Ureshino, Luiz Felipe Pinho Moreira
Publikováno v:
Clinics, Vol 75
Considering that female sexual hormones may modulate the inflammatory response and also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the sex differences and the role of estradiol in modulating the lung and sy
Externí odkaz:
https://doaj.org/article/77f40d38651a4774bb930bfb79d2e0b7
Autor:
Claudia Bincoletto, Gustavo J.S. Pereira, Adolfo Garcia Erustes, Rodrigo Portes Ureshino, Gabriel Cicolin Guarache, Manuela D’Eletto, Soraya S. Smaili, Mauro Piacentini
Publikováno v:
Journal of Neuroscience Research. 99:2932-2947
Mitochondria-associated ER membranes (MAMs) are formed by close and specific components in the contact sites between the endoplasmic reticulum (ER) and mitochondria, which participate in several cell functions, including lipid metabolism, autophagy,
Autor:
Angelica Jardim Costa, Robertha Mariana Rodrigues Lemes, Cynthia Silva Bartolomeo, Tamires Alves Nunes, Gabriela Cruz Pereira, Rafaela Brito Oliveira, Alexandre Lopes Gomes, Soraya Soubhi Smaili, Rui Monteiro de Barros Maciel, Louise Newson, Ana Lopez Ramirez, Liria Hiromi Okuda, Carla Máximo Prado, Roberta Sessa Stilhano, Rodrigo Portes Ureshino
Publikováno v:
Molecular and cellular endocrinology. 558
Gender-bias in COVID-19 severity has been suggested by clinical data. Experimental data in cell and animal models have demonstrated the role of sex hormones, particularly estrogens, in viral infections such as in COVID-19. SARS-CoV-2 uses ACE2 as a r