Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rodrigo Pontiggia"'
Autor:
Rodrigo Pontiggia, Santiago Di Lella, Darío A. Estrin, Javier M. Montserrat, Adolfo M. Iribarren, Joachim W. Engels, Laura Robaldo
Publikováno v:
The Journal of Physical Chemistry B. 117:57-69
The hybridization performance of a set of 12-mer RNA:RNA duplexes containing 2'-C-methyluridine, 5-bromo-2'-C-methyluridine, or (2'S)-2'-deoxy-2'-C-methyluridine was analyzed. Melting point temperatures of the modified duplexes showed an important Δ
Autor:
Luis E. Iglesias, Rodrigo Pontiggia, Javier M. Montserrat, María A. Zinni, Silvio D. Rodríguez, Adolfo M. Iribarren
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 29:129-132
Candida antarctica-B (CAL-B) lipase-catalysed alcoholysis of a set of 3',5'-di-O-acetyl-2'-deoxynucleosides (la-e) gave the corresponding 3'-O-acetyl-2'-deoxy-nucleosides (2a-e) in yields ranging from 50 to 96%. The alcohol employed in the biotransfo
Autor:
Javier M. Montserrat, Marina Simian, Rodrigo Pontiggia, Adolfo M. Iribarren, Joachim W. Engels, Osvaldo Pontiggia
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(9)
A new synthesis of 2′-C-methyluridine phosphoramidite is presented. Special emphasis is dedicated to the improvement of the protection of the tertiary 2′-hydroxyl group. Comparison to previous protecting strategies and analysis of stability under
Publikováno v:
Scopus-Elsevier
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
DNAzymes and Ribozymes find applications as inhibitors of gene expression and in detection systems such as biosensors, among others. In particular, we are interested in the properties of hammerhead ribozymes carrying 2′-C-methylnucleotides and 10
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