Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rodrigo Peña Hernández"'
Publikováno v:
Genomics Data, Vol 4, Iss C, Pp 17-21 (2015)
CTCF is a key regulator of nuclear chromatin structure, chromatin organization and gene regulation. The impact of CTCF on transcriptional output is quite varied, ranging from repression, to transcriptional pausing and transactivation. The multifuncti
Externí odkaz:
https://doaj.org/article/29444bd56e88482aa70c2e4aeb510187
Autor:
Raffaella Santoro, Rodrigo Peña-Hernández, Daniel Spies, Constance Ciaudo, Markus Mueller, M. Schaefer, T. Faeh
The Argonaute proteins (AGO) are well-known for their essential role in post-transcriptional gene silencing in the microRNA (miRNA) biogenesis pathway. Only two AGOs (AGO1 and AGO2) are expressed in mouse embryonic stem cells (mESCs). The transcripto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc06694ec4f29e00dd284ef26a774a66
https://doi.org/10.1101/2021.10.18.464771
https://doi.org/10.1101/2021.10.18.464771
Autor:
Marc W. Schmid, Tuncay Baubec, Raffaella Santoro, Damian Dalcher, Ana C. Marques, Rostyslav Kuzyakiv, Stefan Butz, Valerio Bianchi, Jennifer Y. Tan, Cristiana Bersaglieri, Marcin Roganowicz, Rodrigo Peña-Hernández, Stefan Zeyen, Eva Vollenweider
Publikováno v:
The EMBO Journal
Chromosomes have an intrinsic tendency to segregate into compartments, forming long‐distance contacts between loci of similar chromatin states. How genome compartmentalization is regulated remains elusive. Here, comparison of mouse ground‐state e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1755360ffa7f513ddf732988cf559a0
http://europepmc.org/articles/PMC7705451
http://europepmc.org/articles/PMC7705451
Autor:
Sandra C Frommel, Karolina Pietrzak, Seraina Steiger, Rodrigo Peña-Hernández, Marcin Roganowicz, Raffaella Santoro, Juliana Bizzarro, Rossana Aprigliano
Prostate cancer (PCa) is one of the most prevalent cancers in men. Cancer stem cells are thought to be associated with PCa relapse and represent a target against metastatic PCa. Here we show that BAZ2A (also known as TIP5), a factor previously implic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33ee24a876cf8fbd847d01ca6791efdc
https://doi.org/10.1101/2020.07.03.185843
https://doi.org/10.1101/2020.07.03.185843
Autor:
Stefan Zeyen, Valerio Bianchi, Rodrigo Peña-Hernández, Raffaella Santoro, Eva Vollenweider, Cristiana Bersaglieri, Marc W. Schmid, Rostyslav Kuzyakiv, Damian Dalcher, Jennifer Y. Tan, Tuncay Baubec, Ana C. Marques, Stefan Butz
Chromosomes have an intrinsic tendency to segregate into compartments, forming long-distance contacts between loci of similar chromatin states. However, how genome compartmentalization is regulated remains elusive. We analyzed two closely and develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206975aaaeb6e8625665f879232ee7d7
https://doi.org/10.1101/2019.12.20.882282
https://doi.org/10.1101/2019.12.20.882282
Autor:
Lukas Sommer, Mitchell P. Levesque, Yudong Zhang, Ana T. Antunes, Eylul Tuncer, Kwok-Kin Wong, Rodrigo Peña-Hernández, Konrad Basler, Simon M. Schaefer, Phil F. Cheng, Dario Zimmerli, Raquel R. Calçada, Raphaël Bossart, Jessica Haeusel, Daniel Zingg, Julien Debbache, Reinhard Dummer, Raffaella Santoro
Publikováno v:
Cancer cell. 34(1)
Human melanomas frequently harbor amplifications of EZH2. However, the contribution of EZH2 to melanoma formation has remained elusive. Taking advantage of murine melanoma models, we show that EZH2 drives tumorigenesis from benign BrafV600E- or NrasQ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b187ba8bbaf80c509ded5d2d2d4d446f
https://pubmed.ncbi.nlm.nih.gov/29990499
https://pubmed.ncbi.nlm.nih.gov/29990499
Autor:
Michael Witcher, Amine Saad, Todd Ashworth, Sonia V. del Rincón, Khalid Hilmi, Maud Marques, Moulay A. Alaoui-Jamali, Rodrigo Peña-Hernández, Ananda L. Roy, Beverly M. Emerson, Teijun Zhao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(7)
CCCTC-binding factor (CTCF) is a key regulator of nuclear chromatin structure and gene regulation. The impact of CTCF on transcriptional output is highly varied, ranging from repression to transcriptional pausing and transactivation. The multifunctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd9699744c6fe7997bcf4d55fdd0fbe
https://pubmed.ncbi.nlm.nih.gov/25646466
https://pubmed.ncbi.nlm.nih.gov/25646466
Publikováno v:
Genomics Data
Genomics Data, Vol 4, Iss C, Pp 17-21 (2015)
Genomics Data, Vol 4, Iss C, Pp 17-21 (2015)
CTCF is a key regulator of nuclear chromatin structure, chromatin organization and gene regulation. The impact of CTCF on transcriptional output is quite varied, ranging from repression, to transcriptional pausing and transactivation. The multifuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5a1a11d42f26d022f05f0658873c67
Autor:
Madlen Müller, Moritz Schaefer, Tara Fäh, Daniel Spies, Victoria Hermes, Richard Patryk Ngondo, Rodrigo Peña-Hernández, Raffaella Santoro, Constance Ciaudo
Publikováno v:
Stem Cell Reports, 17 (5)
The Argonaute proteins (AGOs) are well known for their role in post-transcriptional gene silencing in the microRNA (miRNA) pathway. Here we show that in mouse embryonic stem cells, AGO1&2 serve additional functions that go beyond the miRNA pathway. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7cd7ddb0026756e6785331e94e2cf2
Autor:
Sandra C Frommel, Marcin Roganowicz, Luigi Lerra, Raffaella Santoro, Karolina Pietrzak, Rossana Aprigliano, Seraina Steiger, Rodrigo Peña-Hernández, Juliana Bizzarro
Publikováno v:
EMBO Reports
EMBO reports
EMBO reports
Prostate cancer (PCa) is one of the most prevalent cancers in men. Cancer stem cells are thought to be associated with PCa relapse. Here, we show that BAZ2A is required for PCa cells with a cancer stem‐like state. BAZ2A genomic occupancy in PCa cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e27ff0ece415d8b321fcc93b7d9eab