Impact of sex on use of low tidal volume ventilation in invasively ventilated ICU patients-A mediation analysis using two observational cohorts.

Autor: Pien Swart, Rodrigo Octavio Deliberato, Alistair E W Johnson, Tom J Pollard, Lucas Bulgarelli, Paolo Pelosi, Marcelo Gama de Abreu, Marcus J Schultz, Ary Serpa Neto

Publikováno v: PLoS ONE, Vol 16, Iss 7, p e0253933 (2021)

BackgroundStudies in patients receiving invasive ventilation show important differences in use of low tidal volume (VT) ventilation (LTVV) between females and males. The aims of this study were to describe temporal changes in VT and to determine what

Externí odkaz: https://doaj.org/article/fdbd73436382459ca97d8102f014b058

Duration of antibiotic treatment using procalcitonin-guided treatment algorithms in older patients

Autor: Philipp Schuetz, Gaëtan Gavazzi, Rodrigo Octavio Deliberato, Eva Heilmann, Lila Bouadma, Jin-Xiang Wang, Tobias Welte, Florence Tubach, Albertus Beishuizen, Stefan Schroeder, Yahya Shehabi, Konrad Reinhart, Jos A H van Oers, Alessia Verduri, Angela Branche, Stella Sala Soares Lima, Sabine Drevet, Armand R. J. Girbes, Vandack Nobre, Claudia Gregoriano, Kristina B. Kristoffersen, Jean Chastre, Mirjam Christ-Crain, Long Wei, Maarten W. N. Nijsten, Michael Tamm, Caspar Corti, Carolina F. Oliveira, Djillali Annane, Evelien de Jong, Michel Wolff, Charles-Edouard Luyt, Pierre Damas, Beat Mueller, Daiana Stolz, Nathalie Layios, Dylan W. de Lange, Matthias Briel

Publikováno v: Heilmann, E, Gregoriano, C, Annane, D, Reinhart, K, Bouadma, L, Wolff, M, Chastre, J, Luyt, C E, Tubach, F, Branche, A R, Briel, M, Christ-Crain, M, Welte, T, Corti, C, de Jong, E, Nijsten, M, de Lange, D W, van Oers, J A H, Beishuizen, A, Girbes, A R J, Deliberato, R O, Schroeder, S, Kristoffersen, K B, Layios, N, Damas, P, Lima, S S S, Nobre, V, Wei, L, Oliveira, C F, Shehabi, Y, Stolz, D, Tamm, M, Verduri, A, Wang, J X, Drevet, S, Gavazzi, G, Mueller, B & Schuetz, P 2021, ' Duration of antibiotic treatment using procalcitonin-guided treatment algorithms in older patients : a patient-level meta-analysis from randomized controlled trials ', Age and Ageing, vol. 50, no. 5, pp. 1546-1556 . https://doi.org/10.1093/ageing/afab078
Age and Ageing
Heilmann, E, Gregoriano, C, Annane, D, Reinhart, K, Bouadma, L, Wolff, M, Chastre, J, Luyt, C-E, Tubach, F, Branche, A R, Briel, M, Christ-Crain, M, Welte, T, Corti, C, de Jong, E, Nijsten, M, de Lange, D W, van Oers, J A H, Beishuizen, A, Girbes, A R J, Deliberato, R O, Schroeder, S, Kristoffersen, K B, Layios, N, Damas, P, Lima, S S S, Nobre, V, Wei, L, Oliveira, C F, Shehabi, Y, Stolz, D, Tamm, M, Verduri, A, Wang, J-X, Drevet, S, Gavazzi, G, Mueller, B & Schuetz, P 2021, ' Duration of antibiotic treatment using procalcitonin-guided treatment algorithms in older patients : a patient-level meta-analysis from randomized controlled trials ', Age and Ageing, vol. 50, no. 5, pp. 1546-1556 . https://doi.org/10.1093/ageing/afab078

Background Older patients have a less pronounced immune response to infection, which may also influence infection biomarkers. There is currently insufficient data regarding clinical effects of procalcitonin (PCT) to guide antibiotic treatment in olde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8224f5260372d2176a67feda3345f243
http://www.scopus.com/inward/record.url?scp=85116955794&partnerID=8YFLogxK

Developing well-calibrated illness severity scores for decision support in the critically ill

Autor: Aaron R. Kaufman, David J. Stone, Miguel Ángel Armengol de la Hoz, Leo Anthony Celi, Christopher V. Cosgriff, Omar Badawi, Rodrigo Octavio Deliberato, Stephanie Q Ko, Tejas Sundaresan

Publikováno v: npj Digital Medicine, Vol 2, Iss 1, Pp 1-8 (2019)
npj Digital Medicine, ISSN 2398-6352, 2019-08-15, Vol. 2, No. 76
Archivo Digital UPM
Universidad Politécnica de Madrid
NPJ Digital Medicine

Illness severity scores are regularly employed for quality improvement and benchmarking in the intensive care unit, but poor generalization performance, particularly with respect to probability calibration, has limited their use for decision support.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca567e8c4697f119008c2de9bbaa26b1
http://link.springer.com/article/10.1038/s41746-019-0153-6

An Evaluation of the Influence of Body Mass Index on Severity Scoring

Autor: Rodrigo Octavio Deliberato, Alistair E. W. Johnson, Carolina Rodrigues Ponzoni, Lucas Bulgarelli, Matthieu Komorowski, Stephanie Q Ko, Ary Serpa Neto, Leo Anthony Celi, David J. Stone, Renato Carneiro de Freitas Chaves

Publikováno v: Critical care medicine, 47(2), 247-253. Lippincott Williams and Wilkins

OBJECTIVES: Although one third or more of critically ill patients in the United States are obese, obesity is not incorporated as a contributing factor in any of the commonly used severity of illness scores. We hypothesize that selected severity of il

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2acac1938e7527882902c7075df96f63
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85060125323&origin=inward

Prediction on critically ill patients: The role of 'big data'

Autor: Rodrigo Octavio Deliberato, Alistair E. W. Johnson, Lucas Bulgarelli

Publikováno v: Journal of critical care. 60

Accurate outcome prediction in Intensive Care Units (ICUs) would allow for better treatment planning, risk adjustment of study populations, and overall improvements in patient care. In the past, prognostic models have focused on mortality using simpl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2afd73539ffe94ac697d192654ffc40f
https://pubmed.ncbi.nlm.nih.gov/32763775