Výsledky vyhledávání - "Rodrigo O Perez"

Akademický článek

E2F1 somatic mutation within miRNA target site impairs gene regulation in colorectal cancer.

Autor: Camila M Lopes-Ramos, Bruna P Barros, Fernanda C Koyama, Paola A Carpinetti, Julia Pezuk, Nayara T S Doimo, Angelita Habr-Gama, Rodrigo O Perez, Raphael B Parmigiani

Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0181153 (2017)

Genetic studies have largely concentrated on the impact of somatic mutations found in coding regions, and have neglected mutations outside of these. However, 3' untranslated regions (3' UTR) mutations can also disrupt or create miRNA target sites, an

Externí odkaz: https://doaj.org/article/988b14ca22ca43de9b9432ca681bcee3

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Akademický článek

Post-Operative Functional Outcomes in Early Age Onset Rectal Cancer

Autor: REACCT Collaborative, Lauren V. O’Connell, Alexandra M. Zaborowski, Ahmed Abdile, Michel Adamina, Felix Aigner, Laura d’Allens, Caterina Allmer, Andrea Álvarez, Rocio Anula, Mihailo Andric, Sam Atallah Simon Bach, Miklosh Bala, Marie Barussaud, Augustinas Bausys, Andrew Beggs, Felipe Bellolio, Melissa-Rose Bennett, Vicki Bevan, Sebastiano Biondo, Gabriele Bislenghi, Marc Bludau, Carl Brown, Christiane Bruns, Daniel D. Buchanan, Pamela Buchwald, Jacobus W.A. Burger, Nikita Burlov, Michela Campanelli, Maylis Capdepont, Michele Carvello, Hwee-Hoon Chew, Dimitri Christoforidis, David Clark, Marta Climent, Rowan Collinson, Kyle G. Cologne, Tomas Contreras, Roland Croner, Ian R. Daniels, Giovanni Dapri, Justin Davies, Paolo Delrio, Quentin Denost, Michael Deutsch, Andre Dias, André D’Hoore, Evgeniy Drozdov, Daniel Duek, Malcolm Dunlop, Adam Dziki, Aleksandra Edmundson, Sergey Efetov, Alaa El-Hussuna, Brodie Elliott, Sameh Emile, Eloy Espin-Basany, Martyn Evans, Seraina Faes, Omar Faiz, Nuno Figueiredo, Fergal Fleming, Caterina Foppa, George Fowler, Matteo Frasson, Tim Forgan, Frank Frizelle, Shamil Gadaev, Jose Gellona, Tamara Glyn, Barisic Goran, Emma Greenwood, Marianne G. Guren, Stephanie Guillon, Ida Gutlic, Dieter Hahnloser, Heather Hampel, Ann Hanly, Hirotoshi Hasegawa, Lene Hjerrild Iversen, Andrew Hill, James Hill, Jiri Hoch, Roel Hompes, Luis Hurtado, Fabiano Iaquinandi, Ugne Imbrasaite, Rumana Islam, Mehrenah D Jafari, Andrea Jiménez Salido, Marta Jiménez-Toscano, Yukihide Kanemitsu, Aleksei Karachun, Ahmer A. Karimuddin, Deborah S. Keller, Justin Kelly, Rory Kennelly, Gleb Khrykov, Petr Kocian, Cherry Koh, Neils Kok, Katrina A. Knight, Joep Knol, Christos Kontovounisios, Hartwig Korner, Zoran Krivokapic, Irmgard Kronberger, Hidde Maarten Kroon, Marius Kryzauskas, Said Kural, Miranda Kusters, Zaher Lakkis, Timur Lankov, David Larson, György Lázár, Kai-Yin Lee, Suk Hwan Lee, Jérémie H. Lefèvre, Anna Lepisto, Christopher Lieu, Lynette Loi, Craig Lynch, Helene Maillou-Martinaud, Annalisa Maroli, Sean T. Martin, Anna Martling, Klaus E. Matzel, Julio Mayol, Frank McDermott, Guillaume Meurette, Monica Millan, Martin Mitteregger, Andrei Moiseenko, John RT. Monson, Stefan Morarasu, Konosuke Moritani, Gabriela Möslein, Martino Munini, Caio Nahas, Sergio Nahas, Ionut Negoi, Anastasia Novikova, Misael Ocares, Koji Okabayashi, Alexandra Olkina, Luis Oñate-Ocaña, Jaime Otero, Cihan Ozen, Ugo Pace, Guilherme Pagin São Julião, Lidiia Panaiotti, Yves Panis, Demetris Papamichael, Swati Patel, Juan Carlos Patrón Uriburu, Sze-Lin Peng, Miguel Pera, Rodrigo O. Perez, Alexei Petrov, Frank Pfeffer, Terry P. Phang, Tomas Poskus, Heather Pringle, David Proud, Ivana Raguz, Nuno Rama, Shahnawaz Rasheed, Manoj J. Raval, Daniela Rega, Christoph Reissfelder, Juan Carlos Reyes Meneses, Frederic Ris, Stefan Riss, Homero Rodriguez-Zentner, Campbell S Roxburgh, Avanish Saklani, Tarik Sammour, Deborah Saraste, Martin Schneider, Ryo Seishima, Aleksandar Sekulic, Toni Seppala, Kieran Sheahan, Alexandra Shlomina, Guiseppe Sica, Tongplaew Singnomklao, Leandro Siragusa, Neil Smart, Alejandro Solis-Peña, Antonino Spinelli, Roxane D. Staiger, Michael J. Stamos, Scott Steele, Ker-Kan Tan, Pieter J Tanis, Paris Tekkis, Biniam Teklay, Sabrina Tengku, Petr Tsarkov, Matthias Turina, Alexis Ulrich, Bruna B. Vailati, Meike van Harten, Cornelis Verhoef, Satish Warrier, Steven Wexner, Benjamin A. Weinberg, Cameron Wells, Albert Wolthuis, Evangelos Xynos, Nancy You, Alexander Zakharenko, Justino Zeballos, Youzhi Zhou, Des C. Winter

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

BackgroundImpairment of bowel, urogenital and fertility-related function in patients treated for rectal cancer is common. While the rate of rectal cancer in the young (

Externí odkaz: https://doaj.org/article/5415e380928946f688c0470b32ad5d32

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Akademický článek

Role of magnetic resonance imaging in organ-preserving strategies for the management of patients with rectal cancer

Autor: Cinthia D. Ortega, Rodrigo O. Perez

Publikováno v: Insights into Imaging, Vol 10, Iss 1, Pp 1-16 (2019)

Abstract Total mesorectal excision has been the most effective treatment strategy adopted to reduce local recurrence rates among patients with rectal cancer. The morbidity associated with this radical surgical procedure led surgeons to challenge the

Externí odkaz: https://doaj.org/article/3fb1426178334e3cb6e11d74ec820fc3

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Data from A Diagnostic Biopsy-Adapted Immunoscore Predicts Response to Neoadjuvant Treatment and Selects Patients with Rectal Cancer Eligible for a Watch-and-Wait Strategy

Purpose:No biomarker to personalize treatment in locally advanced rectal cancer (LARC) is currently available. We assessed in LARC whether a diagnostic biopsy-adapted immunoscore (ISB) could predict response to neoadjuvant treatment (nT) and better d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ebd87a70c7b7ef844d9ed296e7d0ef
https://doi.org/10.1158/1078-0432.c.6529847.v1

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Supplementary Figures from A Diagnostic Biopsy-Adapted Immunoscore Predicts Response to Neoadjuvant Treatment and Selects Patients with Rectal Cancer Eligible for a Watch-and-Wait Strategy

Supplementary Figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329e044c43773247e79e4b5d3ecf83e9
https://doi.org/10.1158/1078-0432.22478075.v1

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Supplementary Tables from A Diagnostic Biopsy-Adapted Immunoscore Predicts Response to Neoadjuvant Treatment and Selects Patients with Rectal Cancer Eligible for a Watch-and-Wait Strategy

Supplementary Tables

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6463fb370725f6d5f089f6114112316e
https://doi.org/10.1158/1078-0432.22478072

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Watch and wait after neoadjuvant treatment in rectal cancer: comparison of outcomes in patients with and without a complete response at first reassessment in the International Watch & Wait Database (IWWD)

Autor: Sofieke J.D. Temmink, Koen C.M.J Peeters, Renu R. Bahadoer, Elma Meershoek-Klein Kranenburg, Annet G.H. Roodvoets, Jarno Melenhorst, Jacobus W.A. Burger, Albert Wolthuis, Andrew G. Renehan, Nuno L. Figueiredo, Oriol Pares, Anna Martling, Rodrigo O. Perez, Geerard L. Beets, Cornelis J.H. van de Velde, Per J. Nilsson

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2659::b01952d31f9670f25055b066338b5bf1
https://zenodo.org/record/7782139

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Akademický článek

Total mesorectal excision and sphincter preservation — the early steps of rectal cancer surgery

Autor: Rodrigo O. Perez, Guilherme P. São Julião, Igor Proscurshim, Charles Sabbagh, Esteban Grzona, Patricio B. Lynn, Joaqim Gama-Rodrigues

Publikováno v: Journal of Coloproctology, Vol 34, Iss 1, Pp 41-47 (2014)

The treatment of rectal cancer has evolved significantly over the last 100 years. Standardiza- tion of total mesorectal excision and the development of techniques for sphincter preserva- tion have resulted in significant improvements in the managemen

Externí odkaz: https://doaj.org/article/e2a713807a604878aa1b6bca0870a79a

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Akademický článek

Cylindrical abdominoperineal resection rationale, technique and controversies

Autor: Patricio B. Lynn, Angelita Habr-Gama, Rodrigo O. Perez, Esteban Grzona, Charles Sabbagh, Joaquim J. Gama-Rodrigues

Publikováno v: Journal of Coloproctology, Vol 33, Iss 3, Pp 167-173 (2013)

Surgery remains the cornerstone in rectal cancer treatment. Abdominoperineal excision (APE), described more than 100 years ago, remains as an important procedure for the treatment of selected advanced distal tumors with direct invasion of the anal sp

Externí odkaz: https://doaj.org/article/cd8a33182a3043849f731bcb954270b9

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Watch and wait: Why, to whom and how

Autor: Carlos Cerdán-Santacruz, Bruna B. Vailati, Gillherme P. São Julião, Angelita Habr-Gama, Rodrigo O. Perez

Publikováno v: Surgical Oncology. 43:101774

The current standard of care for the treatment of locally advanced rectal cancer includes neoadjuvant chemoradiation (nCRT) followed by total mesorrectal excision (TME). The observation of significant primary tumor response to radiation and chemother

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c11add9028c060cf4e14563872ba761
https://doi.org/10.1016/j.suronc.2022.101774

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