Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Rodrigo M Maza"'
Autor:
Mónica Yunta, Manuel Nieto-Díaz, Francisco J Esteban, Marcos Caballero-López, Rosa Navarro-Ruíz, David Reigada, D Wolfgang Pita-Thomas, Angela del Águila, Teresa Muñoz-Galdeano, Rodrigo M Maza
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34534 (2012)
Spinal cord injury (SCI) triggers a multitude of pathophysiological events that are tightly regulated by the expression levels of specific genes. Recent studies suggest that changes in gene expression following neural injury can result from the dysre
Externí odkaz:
https://doaj.org/article/5ea7ee5e5fb5494db841ddda6e60c33a
Autor:
Wolfgang Pita-Thomas, Carmen Fernández-Martos, Mónica Yunta, Rodrigo M Maza, Rosa Navarro-Ruiz, Marcos Javier Lopez-Rodríguez, David Reigada, Manuel Nieto-Sampedro, Manuel Nieto-Diaz
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15706 (2010)
The annual regeneration cycle of deer (Cervidae, Artiodactyla) antlers represents a unique model of epimorphic regeneration and rapid growth in adult mammals. Regenerating antlers are innervated by trigeminal sensory axons growing through the velvet,
Externí odkaz:
https://doaj.org/article/4d88331d481e4dd294a7c8ba1f29aa52
Autor:
Altea Soto, Manuel Nieto-Díaz, Enrique Martínez-Campos, Ana Noalles-Dols, María Asunción Barreda-Manso, Felipe Reviriego, Helmut Reinecke, David Reigada, Teresa Muñoz-Galdeano, Irene Novillo, Alberto Gallardo, Juan Rodríguez-Hernández, Ramón Eritja, Anna Aviñó, Carlos Elvira, Rodrigo M. Maza
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1451 (2023)
MicroRNAs (miRNAs) are endogenous, short RNA oligonucleotides that regulate the expression of hundreds of proteins to control cells’ function in physiological and pathological conditions. miRNA therapeutics are highly specific, reducing the toxicit
Externí odkaz:
https://doaj.org/article/6e336ec2b6154f558aa9aad96f96bacf
Autor:
Rodrigo M. Maza, María Asunción Barreda-Manso, David Reigada, Ágata Silván, Teresa Muñoz-Galdeano, Altea Soto, Ángela del Águila, Manuel Nieto-Díaz
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1559 (2022)
The central nervous system microRNA miR-138-5p has attracted much attention in cancer research because it inhibits pro-apoptotic genes including CASP3. We hypothesize that miR-138-5p downregulation after SCI leads to overexpression of pro-apoptotic g
Externí odkaz:
https://doaj.org/article/bc7faf3326e64ae2b14a8c259184571d
Autor:
Altea Soto, Manuel Nieto-Díaz, David Reigada, María Asunción Barreda-Manso, Teresa Muñoz-Galdeano, Rodrigo M. Maza
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 529 (2022)
Nogo-A protein is a key myelin-associated inhibitor of axonal growth, regeneration, and plasticity in the central nervous system (CNS). Regulation of the Nogo-A/NgR1 pathway facilitates functional recovery and neural repair after spinal cord trauma a
Externí odkaz:
https://doaj.org/article/bdfc995ec6bb47528b13b7003a2c6f94
Autor:
Teresa Muñoz-Galdeano, David Reigada, María Gamarra, Altea Soto, María Asunción Barreda-Manso, Irene Novillo, Manuel Nieto-Díaz, Rodrigo M. Maza
Altered expression of microRNAs (miRNAs) after spinal cord injury (SCI) has been described as being responsible for the main secondary responses, such as apoptosis. X-linked inhibitor apoptosis protein (XIAP) is a key apoptotic component involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee92c73c71f04d94685ce86cd4230d6
Autor:
David Reigada, Rodrigo M. Maza, Teresa Muñoz-Galdeano, María Asunción Barreda-Manso, Altea Soto, Dan Lindholm, Rosa Navarro-Ruíz, Manuel Nieto-Díaz
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2791
Volume 24
Issue 3
Pages: 2791
Mechanical trauma to the spinal cord causes extensive neuronal death, contributing to the loss of sensory-motor and autonomic functions below the injury location. Apoptosis affects neurons after spinal cord injury (SCI) and is associated with increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf4da330071ec4b8cbcfb29233f1886
https://doi.org/10.20944/preprints202212.0023.v1
https://doi.org/10.20944/preprints202212.0023.v1
Autor:
M. Asunción Barreda-Manso, Altea Soto, Teresa Muñoz-Galdeano, David Reigada, Manuel Nieto-Díaz, Rodrigo M. Maza
Neuronal maturation is a process that plays a key role in the development and regeneration of the central nervous system. Although embryonic brain development and neurodegeneration have received considerable attention, the events that govern postnata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e25b3cc99a703191cd75117186f47e4b
https://doi.org/10.1101/2022.11.15.516547
https://doi.org/10.1101/2022.11.15.516547
Autor:
David Reigada, Vanesa Soto, María González-Rodríguez, María Asunción Barreda-Manso, Altea Soto, Teresa Muñoz-Galdeano, Rodrigo M. Maza, Manuel Nieto-Díaz
Spinal cord injury (SCI) is a major cause of permanent disability and its causes and pathophysiological effects are very variables between patients. The assessment of tissue damage extent and neurodegeneration degree correlated with the functional ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d024e6c5205f57aa4762f524fea2b0a0
https://doi.org/10.1101/2022.05.05.490720
https://doi.org/10.1101/2022.05.05.490720
Autor:
Andrés Ángel Calderón-García, Manuel Nieto-Díaz, Teresa Muñoz-Galdeano, Rodrigo M. Maza, David Reigada, Manuel Soto‐Catalán, Ángela del Águila
Publikováno v:
Journal of Neurochemistry. 151:116-130
Excitotoxic cell death because of the massive release of glutamate and ATP contributes to the secondary extension of cellular and tissue loss following traumatic spinal cord injury (SCI). Evidence from blockage experiments suggests that over-expressi