Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rodrigo Laureano"'
Autor:
Lei Jiang, Ji-Sun Park, Ling Yin, Rodrigo Laureano, Eric Jacquinet, Jinsong Yang, Shi Liang, Andrea Frassetto, Jenny Zhuo, Xinhua Yan, Xuling Zhu, Steven Fortucci, Kara Hoar, Cosmin Mihai, Christopher Tunkey, Vlad Presnyak, Kerry E. Benenato, Christine M. Lukacs, Paolo G. V. Martini, Lin T. Guey
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Propionic acidemia is a serious pediatric inherited disorder with no effective treatments. Here the authors demonstrate that delivering dual mRNAs as an enzyme replacement approach can be used as an effective therapy in a mouse model of propionic aci
Externí odkaz:
https://doaj.org/article/c8fd3846b2b840c782c81abf4afb2075
Autor:
Ding An, Andrea Frassetto, Eric Jacquinet, Marianne Eybye, Joseph Milano, Christine DeAntonis, Vi Nguyen, Rodrigo Laureano, Jaclyn Milton, Staci Sabnis, Christine M. Lukacs, Lin T. Guey
Publikováno v:
EBioMedicine, Vol 45, Iss , Pp 519-528 (2019)
Background: Isolated methylmalonic acidemia/aciduria (MMA) is an ultra-rare, serious, inherited metabolic disorder with significant morbidity and mortality. Exogenously delivered mRNA encoding human methylmalonyl-CoA mutase (hMUT), the enzyme most fr
Externí odkaz:
https://doaj.org/article/12606a1093fa4685ab53d409e920be77
Publikováno v:
Toxicologic Pathology. 48:800-809
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak that started in Wuhan, China, in 2019 resulted in a pandemic not seen for a century, and there is an urgent need to develop safe and efficacious vaccines. The scientific commun
Autor:
Silva, Rodrigo Laureano
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
O presente estudo tem como principal foco abordar se as mídia contribuem para a violência no cotidiano brasileiro por meio da comunicação, nomeadamente as mídia jornalísticas. Para tanto refletimos sobre a manifestação da violência na socied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3eea70761e59a22e8f12c3aab3b3b060
Autor:
Christopher Tunkey, Xinhua Yan, Cosmin Mihai, Ling Yin, Andrea Frassetto, Shi Liang, Lei Jiang, Jenny Zhuo, Xuling Zhu, Steven##Fortucci, Kara Hoar, Paolo Martini, Rodrigo Laureano, Christine Lukacs, Kerry Benenato, Vladimir Presnyak, Ji Sun Park, Lin T. Guey, Eric Jacquinet, Jinsong Yang
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Propionic acidemia/aciduria (PA) is an ultra-rare, life-threatening, inherited metabolic disorder caused by deficiency of the mitochondrial enzyme, propionyl-CoA carboxylase (PCC) composed of six alpha (PCCA) and six beta (PCCB) subunits. We herein r
Autor:
Eric Jacquinet, Vi Nguyen, Ding An, Andrea Frassetto, Jaclyn Milton, Joseph Milano, Christine DeAntonis, Staci Sabnis, Christine Lukacs, Lin T. Guey, Marianne Eybye, Rodrigo Laureano
Publikováno v:
EBioMedicine
Background Isolated methylmalonic acidemia/aciduria (MMA) is an ultra-rare, serious, inherited metabolic disorder with significant morbidity and mortality. Exogenously delivered mRNA encoding human methylmalonyl-CoA mutase (hMUT), the enzyme most fre