Výsledky vyhledávání - "Rodrigo I. Bustos"

Adaptive Responses of Mitochondria to Mild Copper Deprivation Involve Changes in Morphology, OXPHOS Remodeling and Bioenergetics

Autor: Lina María Ruiz, Alvaro A. Elorza, Claudia A. Riedel, Rodrigo I. Bustos, Ricardo Gutierrez-Garcia, Graciela Argüelloa, Erik Jensen, Claudia Hernández, David A. Ferrick, Mauricio González, Felipe Simon, Rodolfo Paredes

Publikováno v: Journal of Cellular Physiology. 229:607-619

Copper is an essential cofactor of complex IV of the electron transfer chain, and it is directly involved in the generation of mitochondrial membrane potential. Its deficiency induces the formation of ROS, large mitochondria and anemia. Thus, there i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dc4fdb02d58edaa1db1aaf6313ead95
https://doi.org/10.1002/jcp.24484

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Non-cytotoxic copper overload boosts mitochondrial energy metabolism to modulate cell proliferation and differentiation in the human erythroleukemic cell line K562

Autor: Erik Jensen, Alvaro M. Gonzalez-Ibanez, German I. Puas, Lina María Ruiz, Alvaro A. Elorza, Yancing Rossel, Rodrigo I. Bustos, David A. Ferrick

Publikováno v: Mitochondrion. 29

Copper is integral to the mitochondrial respiratory complex IV and contributes to proliferation and differentiation, metabolic reprogramming and mitochondrial function. The K562 cell line was exposed to a non-cytotoxic copper overload to evaluate mit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecb060523486837a7c13e6e42457192
https://pubmed.ncbi.nlm.nih.gov/27094959

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Copper deficiency alters cell bioenergetics and induces mitochondrial fusion through up - regulation of mfn2 and opa1 in erythropoietic cells

Autor: Alvaro A. Elorza, Lina María Ruiz, Rodrigo I. Bustos, Felipe Simon, Salvador Rivera, Sebastián Ruiz, David A. Ferrick, Erik Jensen, Claudia A. Riedel

Publikováno v: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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Copper is essential in cell physiology, participating in numerous enzyme reactions. In mitochondria, copper is a cofactor for respiratory complex IV, the cytochrome c oxidase. Low copper content is associated with anemia and the appearance of enlarge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354ce6b93033405b0d6fd4ee35acba9e

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Coordination of Rho and Rac GTPase Function via p190B RhoGAP

Autor: Steen H. Hansen, Marie-Annick Forget, Rodrigo I. Bustos, Jeffrey Settleman

Publikováno v: Current Biology. (20):1606-1611

SummaryThe Rac GTPase regulates Rho signaling in a broad range of physiological settings and in oncogenic transformation [1–3]. Here, we report a novel mechanism by which crosstalk between Rac and Rho GTPases is achieved. Activated Rac1 binds direc

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