Polymorphism analysis of the CTLA-4 gene in paracoccidioidomycosis patients

Autor: Viviane F Lozano, Tulio C Lins, Marcus M Teixeira, Rodrigo G Vieira, Maria Heloisa SL Blotta, Alfredo M Goes, Izabel Cristina R Silva, Rinaldo W Pereira, Anamelia L Bocca, Maria Sueli S Felipe

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 106, Iss 2, Pp 220-226 (2011)

The CTLA-4 protein is expressed in activated T cells and plays an essential role in the immune response through its regulatory effect on T cell activation. Polymorphisms of the CTLA-4 gene have been correlated with autoimmune, neoplastic and infectio

Externí odkaz: https://doaj.org/article/b06b6a6040f94e77902274ff4477e760

Genetic heterogeneity of self-reported ancestry groups in an admixed Brazilian population

Autor: Paulo Gentil, Tulio C. Lins, Rodrigo G. Vieira, Ricardo Jacó de Oliveira, Ricardo Moreno-Lima, Breno Silva de Abreu, Rinaldo Wellerson Pereira

Publikováno v: Journal of Epidemiology

Background: Population stratification is the main source of spurious results and poor reproducibility in genetic association findings. Population heterogeneity can be controlled for by grouping individuals in ethnic clusters; however, in admixed popu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a8a243555b466739afb733c33c209b
https://pubmed.ncbi.nlm.nih.gov/21498954

Allele and haplotype frequency distribution in PTPN22 gene across variable ethnic groups: Implications for genetic association studies for autoimmune diseases

Autor: Tulio C. Lins, Dario Grattapaglia, Rinaldo Wellerson Pereira, Rodrigo G. Vieira

Publikováno v: Autoimmunity. 43(4)

The rs2476601-T allele at the protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene has been consistently associated with several autoimmune diseases in European-derived populations. However, little is known about the allele and haplotype f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83aa71cf5ba3272ce45b608338444a2
https://pubmed.ncbi.nlm.nih.gov/20166877

Association of serum lipid components and obesity with genetic ancestry in an admixed population of elderly women

Autor: Alause S. Pires, Clayton Franco Moraes, Rodrigo G. Vieira, Tulio C. Lins, Otávio de Toledo Nóbrega, Roberta Silva Paula, Rinaldo Wellerson Pereira, Lucy Gomes Vianna

Publikováno v: ResearcherID
Genetics and Molecular Biology
Repositório Institucional da UnB
Universidade de Brasília (UnB)
instacron:UNB
Genetics and Molecular Biology, Volume: 35, Issue: 3, Pages: 575-582, Published: 13 JUL 2012
Genetics and Molecular Biology v.35 n.3 2012
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Vol 35, Iss 3, Pp 575-582 (2012)

The prevalence of metabolic disorders varies among ethnic populations and these disorders represent a critical health care issue for elderly women. This study investigated the correlation between genetic ancestry and body composition, metabolic trait

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61b0e8b4fcbaf1a642d905fd4549640
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000307726400005&KeyUID=WOS:000307726400005