Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Rodrigo Entrialgo-Cadierno"'
Autor:
Irati Macaya, Marta Roman, Connor Welch, Rodrigo Entrialgo-Cadierno, Marina Salmon, Alba Santos, Iker Feliu, Joanna Kovalski, Ines Lopez, Maria Rodriguez-Remirez, Sara Palomino-Echeverria, Shane M. Lonfgren, Macarena Ferrero, Silvia Calabuig, Iziar A. Ludwig, David Lara-Astiaso, Eloisa Jantus-Lewintre, Elizabeth Guruceaga, Shruthi Narayanan, Mariano Ponz-Sarvise, Antonio Pineda-Lucena, Fernando Lecanda, Davide Ruggero, Purvesh Khatri, Enrique Santamaria, Joaquin Fernandez-Irigoyen, Irene Ferrer, Luis Paz-Ares, Matthias Drosten, Mariano Barbacid, Ignacio Gil-Bazo, Silve Vicent
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Drug combinations are key to circumvent resistance mechanisms compromising response to single anti-cancer targeted therapies. The implementation of combinatorial approaches involving MEK1/2 or KRASG12C inhibitors in the context of KRAS-mutat
Externí odkaz:
https://doaj.org/article/e4df0207a07b4df791d9fb4bec0b4c62
Autor:
Rodrigo Entrialgo-Cadierno, Cristina Cueto-Ureña, Connor Welch, Iker Feliu, Irati Macaya, Laura Vera, Xabier Morales, Sandra Vietti Michelina, Pietro Scaparone, Ines Lopez, Elodie Darbo, Oihane Erice, Adrian Vallejo, Haritz Moreno, Ainhoa Goñi-Salaverri, David Lara-Astiaso, Nils Halberg, Ivan Cortes-Dominguez, Elizabeth Guruceaga, Chiara Ambrogio, Fernando Lecanda, Silve Vicent
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-23 (2023)
Abstract Background The discovery of functionally relevant KRAS effectors in lung and pancreatic ductal adenocarcinoma (LUAD and PDAC) may yield novel molecular targets or mechanisms amenable to inhibition strategies. Phospholipids availability has b
Externí odkaz:
https://doaj.org/article/4f6be978317d4dc0ae3c2a262e7964af
Autor:
Rodrigo Entrialgo‑Cadierno, Cristina Cueto‑Ureña, Connor Welch, Iker Feliu, Irati Macaya, Laura Vera, Xabier Morales, Sandra Vietti Michelina, Pietro Scaparone, Ines Lopez, Elodie Darbo, Oihane Erice, Adrian Vallejo, Haritz Moreno, Ainhoa Goñi‑Salaverri, David Lara‑Astiaso, Nils Halberg, Ivan Cortes‑Dominguez, Elizabeth Guruceaga, Chiara Ambrogio, Fernando Lecanda, Silve Vicent
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/05018549b48a4e08a6c7bb8bdcca3266
Autor:
Javier Fernández, Blanca Silván, Rodrigo Entrialgo-Cadierno, Claudio J. Villar, Raffaele Capasso, José Antonio Uranga, Felipe Lombó, Raquel Abalo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 143, Iss , Pp 112241- (2021)
Flavonoids are plant bioactive compounds of great interest in nutrition and pharmacology, due to their remarkable properties as antioxidant, anti-inflammatory, antibacterial, antifungal and antitumor drugs. More than 5000 different flavonoids exist i
Externí odkaz:
https://doaj.org/article/8be49f4fd38b426ca4ccb9bd02d84bcb
Autor:
Laura Marín, Ignacio Gutiérrez-Del-Río, Rodrigo Entrialgo-Cadierno, Claudio J Villar, Felipe Lombó
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207278 (2018)
Flavonols are a flavonoid subfamily widely distributed in plants, including several ones of great importance in human and animal diet (apple, tomato, broccoli, onion, beans, tea). These polyphenolic nutraceuticals exert potent antimicrobial (membrane
Externí odkaz:
https://doaj.org/article/3f74bcbea5cd4eba968cecb2631107e4
Autor:
Silve Vicent, Mariano Ponz-Sarvise, Vincenzo Corbo, Jens T. Siveke, Aldo Scarpa, Fernando Lecanda, Purvesh Khatri, Daniel Öhlund, Irati Macaya, Ester Blanco, Karmele Valencia, Haritz Moreno, Marija Trajkovic-Arsic, Pietro Delfino, Elizabeth Guruceaga, Caterina Vicentini, Antonia Malinova, Rodrigo Entrialgo-Cadierno, Iker Feliu, Shruthi Narayanan, Oihane Erice
Suppl. Figure 3. A. Immunoblot of LAMC2 upon Lamc2 knockdown by a specific shRNA in 511950 and PM12167 PDAC mouse cell lines. B. Quantification of organoid number upon LAMC2 knockdown by a specific shRNA in 511950 and PM12167 PDAC mouse cell lines.C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241af947e69570b728e188ae14ec23c1
https://doi.org/10.1158/1078-0432.22490566
https://doi.org/10.1158/1078-0432.22490566
Autor:
Silve Vicent, Mariano Ponz-Sarvise, Vincenzo Corbo, Jens T. Siveke, Aldo Scarpa, Fernando Lecanda, Purvesh Khatri, Daniel Öhlund, Irati Macaya, Ester Blanco, Karmele Valencia, Haritz Moreno, Marija Trajkovic-Arsic, Pietro Delfino, Elizabeth Guruceaga, Caterina Vicentini, Antonia Malinova, Rodrigo Entrialgo-Cadierno, Iker Feliu, Shruthi Narayanan, Oihane Erice
This file includes the Suppl. Methods, Table (1) and References
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2fb169155229fbe80a123105115489
https://doi.org/10.1158/1078-0432.22490548
https://doi.org/10.1158/1078-0432.22490548
Autor:
Silve Vicent, Mariano Ponz-Sarvise, Vincenzo Corbo, Jens T. Siveke, Aldo Scarpa, Fernando Lecanda, Purvesh Khatri, Daniel Öhlund, Irati Macaya, Ester Blanco, Karmele Valencia, Haritz Moreno, Marija Trajkovic-Arsic, Pietro Delfino, Elizabeth Guruceaga, Caterina Vicentini, Antonia Malinova, Rodrigo Entrialgo-Cadierno, Iker Feliu, Shruthi Narayanan, Oihane Erice
Purpose:The identification of pancreatic ductal adenocarcinoma (PDAC) dysregulated genes may unveil novel molecular targets entering inhibitory strategies. Laminins are emerging as potential targets in PDAC given their role as diagnostic and prognost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991d0dce0ccadf3f4d85d52da22204b0
https://doi.org/10.1158/1078-0432.c.6533179.v1
https://doi.org/10.1158/1078-0432.c.6533179.v1
Autor:
Oihane Erice, Shruthi Narayanan, Iker Feliu, Rodrigo Entrialgo-Cadierno, Antonia Malinova, Caterina Vicentini, Elizabeth Guruceaga, Pietro Delfino, Marija Trajkovic-Arsic, Haritz Moreno, Karmele Valencia, Ester Blanco, Irati Macaya, Daniel Öhlund, Purvesh Khatri, Fernando Lecanda, Aldo Scarpa, Jens T. Siveke, Vincenzo Corbo, Mariano Ponz-Sarvise, Silve Vicent
Purpose:The identification of pancreatic ductal adenocarcinoma (PDAC) dysregulated genes may unveil novel molecular targets entering inhibitory strategies. Laminins are emerging as potential targets in PDAC given their role as diagnostic and prognost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa5bbf4b2339f0fdd552b0e61962e95
https://hdl.handle.net/11562/1082055
https://hdl.handle.net/11562/1082055
Autor:
Adrian Vallejo, Pawel K. Mazur, Kaja Kostyrko, Fernando Lecanda, Anuradha Tathireddy, O. Erice, Rita Fragoso, Jun Lu, E. Alejandro Sweet-Cordero, Karmele Valencia, Nerea Razquin, Chang-Zheng Chen, Mariano Ponz-Sarvise, Puri Fortes, Natasha M. Flores, Alex G. Lee, Silvestre Vicent, Tian Qiang Sun, Marta Roman, Simone Hausmann, Elizabeth Guruceaga, Itziar Migueliz, Rodrigo Entrialgo-Cadierno, Leanne C. Sayles
Publikováno v:
The Journal of Clinical Investigation
Few therapies are currently available for patients with KRAS-driven cancers, highlighting the need to identify new molecular targets that modulate central downstream effector pathways. Here we found that the microRNA (miRNA) cluster including miR181a