Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Rodrigo A. Quintanilla"'
Autor:
Tanhia F. Alvear, Arantza Farias-Pasten, Sergio A. Vergara, Juan Prieto-Villalobos, Antonia Silva-Contreras, Fernando A. Fuenzalida, Rodrigo A. Quintanilla, Juan A. Orellana
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Alcohol, a toxic and psychoactive substance with addictive properties, severely impacts life quality, leading to significant health, societal, and economic consequences. Its rapid passage across the blood-brain barrier directly affects different brai
Externí odkaz:
https://doaj.org/article/3fedca9c8f814bfba07c75ceaeacd11e
Autor:
Coram Guevara, Sinay C. Vicencio, Ignacio S. Pizarro, Francisca Villavicencio-Tejo, Rodrigo A. Quintanilla, Pablo Astudillo, Estibaliz Ampuero, Rodrigo Varas, Juan A. Orellana, Fernando C. Ortiz
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 914 (2024)
Multiple sclerosis (MS) is a chronic and degenerative disease that impacts central nervous system (CNS) function. One of the major characteristics of the disease is the presence of regions lacking myelin and an oxidative and inflammatory environment.
Externí odkaz:
https://doaj.org/article/c07f6615a3a7460a897342cd1cf8ce53
Autor:
Esteban Díaz-Jara, Katherine Pereyra, Sinay Vicencio, Margrethe A. Olesen, Karla G. Schwarz, Camilo Toledo, Hugo S. Díaz, Rodrigo A. Quintanilla, Rodrigo Del Rio
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 102992- (2024)
Aims: In mammals, central chemoreception plays a crucial role in the regulation of breathing function in both health and disease conditions. Recently, a correlation between high levels of superoxide anion (O2.-) in the Retrotrapezoid nucleus (RTN), a
Externí odkaz:
https://doaj.org/article/6ba38921a7294a5c9e6a4d0245de337d
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-25 (2022)
Abstract Neurological disorders (NDs) are characterized by progressive neuronal dysfunction leading to synaptic failure, cognitive impairment, and motor injury. Among these diseases, Alzheimer's disease (AD), Parkinson's disease (PD), Huntington’s
Externí odkaz:
https://doaj.org/article/f5fb34bcdf55463f9a5ef6277056b360
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 403 (2023)
Traumatic brain injury (TBI) is brain damage due to external forces. Mild TBI (mTBI) is the most common form of TBI, and repeated mTBI is a risk factor for developing neurodegenerative diseases. Several mechanisms of neuronal damage have been describ
Externí odkaz:
https://doaj.org/article/b535e7ccff1e46bf82dba1a9f5d1f8a4
Autor:
Paloma P. Maldonado, Coram Guevara, Margrethe A. Olesen, Juan Andres Orellana, Rodrigo A. Quintanilla, Fernando C. Ortiz
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1146 (2022)
Multiple sclerosis (MS) encompasses a chronic, irreversible, and predominantly immune-mediated disease of the central nervous system that leads to axonal degeneration, neuronal death, and several neurological symptoms. Although various immune therapi
Externí odkaz:
https://doaj.org/article/1120f8e77c7d496ca2d4c6ed1ecab2db
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2021)
Aging is an irreversible process and the primary risk factor for the development of neurodegenerative diseases, such as Alzheimer’s disease (AD). Mitochondrial impairment is a process that generates oxidative damage and ATP deficit; both factors ar
Externí odkaz:
https://doaj.org/article/77654832d3ca4a8797f7be87133bb7bb
Autor:
Katherin V. Pereyra, David C. Andrade, Camilo Toledo, Karla G. Schwarz, Atenea Uribe-Ojeda, Angélica P. Ríos-Gallardo, Rodrigo A. Quintanilla, Samuel Contreras, Andrea Mahn, Rodrigo Del Rio
Publikováno v:
Journal of Functional Foods, Vol 75, Iss , Pp 104267- (2020)
Cardiac arrythmias play a critical role in several pathological conditions. Importantly, increased arrhythmic risk is associated with systemic oxidative stress and activation of the autonomic nervous system. Thus, we hypothesized that dietary antioxi
Externí odkaz:
https://doaj.org/article/71d14b006547495ba3d48b06c53e81e6
Autor:
Francisca Villavicencio-Tejo, Margrethe A. Olesen, Alejandra Aránguiz, Rodrigo A. Quintanilla
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 515 (2022)
Alzheimer’s disease (AD) is characterized by memory and cognitive impairment, accompanied by the accumulation of extracellular deposits of amyloid β-peptide (Aβ) and the presence of neurofibrillary tangles (NFTs) composed of pathological forms of
Externí odkaz:
https://doaj.org/article/04028c56d8da461eae9a937e53b717e3
Autor:
Rodrigo A. Quintanilla, Carola Tapia-Monsalves, Erick H. Vergara, María José Pérez, Alejandra Aranguiz
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Mitochondria are highly specialized organelles essential for the synapse, and their impairment contributes to the neurodegeneration in Alzheimer’s disease (AD). Previously, we studied the role of caspase-3–cleaved tau in mitochondrial dysfunction
Externí odkaz:
https://doaj.org/article/d967ec8aff044517a8f7d4f1338203dc