Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Rodrigo A Panepucci"'
Autor:
Lorena L de Figueiredo-Pontes, Patricia A Assis, Bárbara A A Santana-Lemos, Rafael H Jácomo, Ana Sílvia G Lima, Aglair B Garcia, Carolina H Thomé, Amélia G Araújo, Rodrigo A Panepucci, Marco A Zago, Arnon Nagler, Roberto P Falcão, Eduardo M Rego
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26713 (2011)
Promyelocytic leukemia-retinoic acid receptor alpha (PML-RARα) expression in acute promyelocytic leukemia (APL) impairs transforming growth factor beta (TGFβ) signaling, leading to cell growth advantage. Halofuginone (HF), a low-molecular-weight al
Externí odkaz:
https://doaj.org/article/c92e0b8c5a3d4c8d8b7ef1a9b6cf080e
Autor:
Flávia Gaona Oliveira, Júlio Cesar Rosa-e-Silva, Alexandra Galvão Gomes, Juliana Dourado Grzesiuk, Thiago Vidotto, Jeremy Andrew Squire, Rodrigo Alexandre Panepucci, Juliana Meola, Lúcia Martelli
Publikováno v:
Revista Brasileira de Ginecologia e Obstetrícia, Vol 46 (2024)
Abstract Endometriosis is a complex disease that affects 10-15% of women of reproductive age. Familial studies show that relatives of affected patients have a higher risk of developing the disease, implicating a genetic role for this disorder. Little
Externí odkaz:
https://doaj.org/article/c2183d27e75649eaabab77e1ff1cf12d
Autor:
Aline Simoneti Fonseca, Anelisa Ramão, Matheus Carvalho Bürger, Jorge Estefano Santana de Souza, Dalila Lucíola Zanette, Greice Andreotti de Molfetta, Luiza Ferreira de Araújo, Rafaela de Barros e Lima Bueno, Graziela Moura Aguiar, Jessica Rodrigues Plaça, Cleidson de Pádua Alves, Anemari Ramos Dinarte dos Santos, Daniel Onofre Vidal, Gyl Eanes Barros Silva, Rodrigo Alexandre Panepucci, Fernanda Maris Peria, Omar Feres, José Joaquim Ribeiro da Rocha, Marco Antonio Zago, Wilson Araújo Silva
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background Colorectal cancer (CRC) is one of the most common cancers worldwide; it is the fourth leading cause of death in the world and the third in Brazil. Mutations in the APC, DCC, KRAS and TP53 genes have been associated with the progre
Externí odkaz:
https://doaj.org/article/714a3d32697943ac85805bff473fd4b1
Autor:
Amandda Évelin Silva-Carvalho, Leane Perim Rodrigues, Josiane Lilian Schiavinato, Marcos Rodrigo Alborghetti, Gustavo Bettarello, Belinda Pinto Simões, Francisco de Assis Rocha Neves, Rodrigo Alexandre Panepucci, Juliana Lott de Carvalho, Felipe Saldanha-Araujo
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Background Mesenchymal stem cell (MSC) therapy is an important alternative for GVHD treatment, but a third of patients fail to respond to such therapy. Therefore, strategies to enhance the immunosuppressive potential of MSCs constitute an ac
Externí odkaz:
https://doaj.org/article/1ac9bfaaba884efb95a2115050a98a84
Autor:
Danuta Sastre, João Baiochi, Ildercilio Mota de Souza Lima, Felipe Canto de Souza, Amanda Cristina Corveloni, Carolina Hassib Thomé, Vitor Marcel Faça, Josiane Lilian dos Santos Schiavinato, Dimas Tadeu Covas, Rodrigo Alexandre Panepucci
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-16 (2019)
Abstract Background Colorectal cancer (CRC) is still a leading cause of death worldwide. Recent studies have pointed to an important role of microRNAs in carcinogenesis. Several microRNAs are described as aberrantly expressed in CRC tissues and in th
Externí odkaz:
https://doaj.org/article/aa062f9f6306436cb8537f05953670a6
Autor:
Josiane Lilian dos Santos Schiavinato, Rodrigo Haddad, Felipe Saldanha-Araujo, João Baiochi, Amélia Goes Araujo, Priscila Santos Scheucher, Dimas Tadeu Covas, Marco Antonio Zago, Rodrigo Alexandre Panepucci
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Regulatory T cells (Tregs) are essential regulators of immune tolerance. atRA and TGF-β can inhibit the polarization of naïve T cells into inflammatory Th17 cells, favoring the generation of stable iTregs, however the regulatory mechanisms
Externí odkaz:
https://doaj.org/article/5558f06850b1423887977055c6ff49cd
Autor:
Bruno Sangiorgi, Felipe Canto de Souza, Ildercílio Mota de Souza Lima, Josiane Lilian dos Santos Schiavinato, Amanda Cristina Corveloni, Carolina Hassibe Thomé, Wilson Araújo Silva, Vitor Marcel Faça, Dimas Tadeu Covas, Marco Antônio Zago, Rodrigo Alexandre Panepucci
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Head and neck squamous cell carcinoma (HNSCC) is among the most common cancer types. Metastasis, the main cause of death by cancer, can be promoted by an inflammatory microenvironment, which induces epithelial-mesenchymal transition (EMT) through a N
Externí odkaz:
https://doaj.org/article/c5a14e51531b4d6ba586ec27927907da
Autor:
Lindolfo da Silva Meirelles, Tathiane Maistro Malta, Rodrigo Alexandre Panepucci, Wilson Araújo da Silva, Jr.
Publikováno v:
Genomics Data, Vol 7, Iss , Pp 20-25 (2016)
Mesenchymal stromal cells (MSCs), sometimes called mesenchymal stem cells, are cultured cells able to give rise to mature mesenchymal cells such as adipocytes, osteoblasts, and chondrocytes, and to secrete a wide range of trophic and immunomodulatory
Externí odkaz:
https://doaj.org/article/0c7df6e4cb514ab187f582470e8cddf6
Autor:
Jessica Rodrigues Plaça, Rafaela de Barros e Lima Bueno, Daniel Guariz Pinheiro, Rodrigo Alexandre Panepucci, Luiza Ferreira de Araújo, Rui Celso Martins Mamede, David Livingstone Alves Figueiredo, Wilson Araújo Silva Jr
Publikováno v:
Genomics Data, Vol 5, Iss C, Pp 9-12 (2015)
Laryngeal squamous cell carcinoma (LSCC) is one of the most common malignancies of the head and neck tumors Zhang et al., 2013 [1]). Previous studies have associated its occurrence with social activities, such as tobacco and alcohol consumption (Hash
Externí odkaz:
https://doaj.org/article/ff66f8adf48a44db89b4abb198c0cb40
Publikováno v:
Stem Cells International, Vol 2016 (2016)
In the last decade, the immunomodulatory properties of mesenchymal stromal cells (MSCs) have attracted a lot of attention, due to their potential applicability in the treatment of graft-versus-host disease (GVHD), a condition frequently associated wi
Externí odkaz:
https://doaj.org/article/3b2003ef0544404d99c53c4c3fa967ce