Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Rodrigo A Panepucci"'
Autor:
Flávia Gaona Oliveira, Júlio Cesar Rosa-e-Silva, Alexandra Galvão Gomes, Juliana Dourado Grzesiuk, Thiago Vidotto, Jeremy Andrew Squire, Rodrigo Alexandre Panepucci, Juliana Meola, Lúcia Martelli
Publikováno v:
Revista Brasileira de Ginecologia e Obstetrícia, Vol 46 (2024)
Abstract Endometriosis is a complex disease that affects 10-15% of women of reproductive age. Familial studies show that relatives of affected patients have a higher risk of developing the disease, implicating a genetic role for this disorder. Little
Externí odkaz:
https://doaj.org/article/c2183d27e75649eaabab77e1ff1cf12d
Autor:
Aline Simoneti Fonseca, Anelisa Ramão, Matheus Carvalho Bürger, Jorge Estefano Santana de Souza, Dalila Lucíola Zanette, Greice Andreotti de Molfetta, Luiza Ferreira de Araújo, Rafaela de Barros e Lima Bueno, Graziela Moura Aguiar, Jessica Rodrigues Plaça, Cleidson de Pádua Alves, Anemari Ramos Dinarte dos Santos, Daniel Onofre Vidal, Gyl Eanes Barros Silva, Rodrigo Alexandre Panepucci, Fernanda Maris Peria, Omar Feres, José Joaquim Ribeiro da Rocha, Marco Antonio Zago, Wilson Araújo Silva
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background Colorectal cancer (CRC) is one of the most common cancers worldwide; it is the fourth leading cause of death in the world and the third in Brazil. Mutations in the APC, DCC, KRAS and TP53 genes have been associated with the progre
Externí odkaz:
https://doaj.org/article/714a3d32697943ac85805bff473fd4b1
Autor:
Amandda Évelin Silva-Carvalho, Leane Perim Rodrigues, Josiane Lilian Schiavinato, Marcos Rodrigo Alborghetti, Gustavo Bettarello, Belinda Pinto Simões, Francisco de Assis Rocha Neves, Rodrigo Alexandre Panepucci, Juliana Lott de Carvalho, Felipe Saldanha-Araujo
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Background Mesenchymal stem cell (MSC) therapy is an important alternative for GVHD treatment, but a third of patients fail to respond to such therapy. Therefore, strategies to enhance the immunosuppressive potential of MSCs constitute an ac
Externí odkaz:
https://doaj.org/article/1ac9bfaaba884efb95a2115050a98a84
Autor:
Danuta Sastre, João Baiochi, Ildercilio Mota de Souza Lima, Felipe Canto de Souza, Amanda Cristina Corveloni, Carolina Hassib Thomé, Vitor Marcel Faça, Josiane Lilian dos Santos Schiavinato, Dimas Tadeu Covas, Rodrigo Alexandre Panepucci
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-16 (2019)
Abstract Background Colorectal cancer (CRC) is still a leading cause of death worldwide. Recent studies have pointed to an important role of microRNAs in carcinogenesis. Several microRNAs are described as aberrantly expressed in CRC tissues and in th
Externí odkaz:
https://doaj.org/article/aa062f9f6306436cb8537f05953670a6
Autor:
Ildercílio Mota de Souza Lima, Josiane Lilian dos Santos Schiavinato, Sarah Blima Paulino Leite, Danuta Sastre, Hudson Lenormando de Oliveira Bezerra, Bruno Sangiorgi, Amanda Cristina Corveloni, Carolina Hassibe Thomé, Vitor Marcel Faça, Dimas Tadeu Covas, Marco Antônio Zago, Mauro Giacca, Miguel Mano, Rodrigo Alexandre Panepucci
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-18 (2019)
Abstract Background By post-transcriptionally regulating multiple target transcripts, microRNAs (miRNAs or miR) play important biological functions. H1 embryonic stem cells (hESCs) and NTera-2 embryonal carcinoma cells (ECCs) are two of the most wide
Externí odkaz:
https://doaj.org/article/a162cd7d17324b50b3151704aca1183d
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-21 (2019)
Abstract Thoroughly understanding the molecular mechanisms responsible for the biological properties of pluripotent stem cells, as well as for the processes involved in reprograming, differentiation, and transition between Naïve and Primed pluripote
Externí odkaz:
https://doaj.org/article/3c8c6e27bc9442228d8c8772baf9963b
Autor:
Josiane Lilian dos Santos Schiavinato, Rodrigo Haddad, Felipe Saldanha-Araujo, João Baiochi, Amélia Goes Araujo, Priscila Santos Scheucher, Dimas Tadeu Covas, Marco Antonio Zago, Rodrigo Alexandre Panepucci
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Regulatory T cells (Tregs) are essential regulators of immune tolerance. atRA and TGF-β can inhibit the polarization of naïve T cells into inflammatory Th17 cells, favoring the generation of stable iTregs, however the regulatory mechanisms
Externí odkaz:
https://doaj.org/article/5558f06850b1423887977055c6ff49cd
Autor:
Mariane Serra Fráguas, Reto Eggenschwiler, Jeannine Hoepfner, Josiane Lilian dos Santos Schiavinato, Rodrigo Haddad, Lucila Habib Bourguignon Oliveira, Amélia Góes Araújo, Marco Antônio Zago, Rodrigo Alexandre Panepucci, Tobias Cantz
Publikováno v:
Stem Cell Research, Vol 19, Iss , Pp 21-30 (2017)
Somatic cell reprogramming by transcription factors and other modifiers such as microRNAs has opened broad avenues for the study of developmental processes, cell fate determination, and interplay of molecular mechanisms in signaling pathways. However
Externí odkaz:
https://doaj.org/article/e8f735aea86e43348f7282c4f0d2063d
Autor:
Bruno Sangiorgi, Felipe Canto de Souza, Ildercílio Mota de Souza Lima, Josiane Lilian dos Santos Schiavinato, Amanda Cristina Corveloni, Carolina Hassibe Thomé, Wilson Araújo Silva, Vitor Marcel Faça, Dimas Tadeu Covas, Marco Antônio Zago, Rodrigo Alexandre Panepucci
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Head and neck squamous cell carcinoma (HNSCC) is among the most common cancer types. Metastasis, the main cause of death by cancer, can be promoted by an inflammatory microenvironment, which induces epithelial-mesenchymal transition (EMT) through a N
Externí odkaz:
https://doaj.org/article/c5a14e51531b4d6ba586ec27927907da
Autor:
Lindolfo da Silva Meirelles, Tathiane Maistro Malta, Rodrigo Alexandre Panepucci, Wilson Araújo da Silva, Jr.
Publikováno v:
Genomics Data, Vol 7, Iss , Pp 20-25 (2016)
Mesenchymal stromal cells (MSCs), sometimes called mesenchymal stem cells, are cultured cells able to give rise to mature mesenchymal cells such as adipocytes, osteoblasts, and chondrocytes, and to secrete a wide range of trophic and immunomodulatory
Externí odkaz:
https://doaj.org/article/0c7df6e4cb514ab187f582470e8cddf6