Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Rodrigo A Matus Nicodemos"'
Autor:
Rodrigo A Matus Nicodemos, David Ambrozak, Amy Ransier, Samuel Darko, Daniel C Douek, Richard A Koup
Publikováno v:
The Journal of Immunology. 206:20.17-20.17
Lentiviruses encode non-structural accessory proteins that function to counteract host restriction factors. The lentivirus protein Vpr is known to block G2 to M transition of the cell cycle and degrades various host DNA repair proteins, including UNG
Publikováno v:
The Journal of Immunology. 202:197.3-197.3
In HIV-infected people, the virus persists in resting memory CD4 T cells as a latent provirus integrated into transcribed genes. HIV has 9 gene products that are generated from 7 alternatively spliced mRNAs whose expression is regulated by the cell