Immune responses during COVID-19 breakthrough cases in vaccinated children and adolescents

Autor: Daniela Rivera-Pérez, Constanza Méndez, Benjamín Diethelm-Varela, Felipe Melo-González, Yaneisi Vázquez, Xing Meng, Qianqian Xin, Rodrigo A. Fasce, Jorge Fernández, Judith Mora, Eugenio Ramirez, Mónica L. Acevedo, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Patricio Astudillo, Nicole Le Corre, Katia Abarca, Cecilia Perret, Pablo A. González, Jorge A. Soto, Susan M. Bueno, Alexis M. Kalergis

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

BackgroundVaccine effectiveness against SARS-CoV-2 infection has been somewhat limited due to the widespread dissemination of the Omicron variant, its subvariants, and the immune response dynamics of the naturally infected with the virus.MethodsTwelv

Externí odkaz: https://doaj.org/article/7c001b5b42b5457faed5b3a10f22f0e2

Humoral and cellular response induced by a second booster of an inactivated SARS-CoV-2 vaccine in adultsResearch in context

Autor: Constanza Méndez, Hernán F. Peñaloza, Bárbara M. Schultz, Alejandro Piña-Iturbe, Mariana Ríos, Daniela Moreno-Tapia, Patricia Pereira-Sánchez, Diane Leighton, Claudia Orellana, Consuelo Covarrubias, Nicolás M.S. Gálvez, Jorge A. Soto, Luisa F. Duarte, Daniela Rivera-Pérez, Yaneisi Vázquez, Alex Cabrera, Sergio Bustos, Carolina Iturriaga, Marcela Urzua, María S. Navarrete, Álvaro Rojas, Rodrigo A. Fasce, Jorge Fernández, Judith Mora, Eugenio Ramírez, Aracelly Gaete-Argel, Mónica Acevedo, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Daniela Weiskopf, Alba Grifoni, Alessandro Sette, Gang Zeng, Weining Meng, José V. González-Aramundiz, Pablo A. González, Katia Abarca, Felipe Melo-González, Susan M. Bueno, Alexis M. Kalergis, María Soledad Navarrete, Constanza Del Río, Dinely Del Pino, Natalia Aguirre, Grecia Salinas, Franco Vega, Acsa Salgado, Thomas Quinteros, Marlene Ortiz, Marcela Puente, Alma Muñoz, Patricio Astudillo, Nicole Le Corre, Marcela Potin, Juan Catalán, Melan Peralta, Consuelo Zamanillo, Nicole Keller, Rocío Fernández, Sofía Aljaro, Sofía López, José Tomás González, Tania Weil, Luz Opazo, Paula Muñoz, Inés Estay, Miguel Cantillana, Liliana Carrera, Matías Masalleras, Paula Guzmán, Francisca Aguirre, Aarón Cortés, Luis Federico Bátiz, Javiera Pérez, Karen Apablaza, Lorena Yates, María de los Ángeles Valdés, Bernardita Hurtado, Veronique Venteneul, Constanza Astorga, Paula Muñoz-Venturelli, Pablo A. Vial, Andrea Schilling, Daniela Pavez, Inia Pérez, Amy Riviotta, Francisca González, Francisca Urrutia, Alejandra Del Río, Claudia Asenjo, Bárbara Vargas, Francisca Castro, Alejandra Acuña, Javiera Guzmán, Camila Astudillo, Carlos M. Pérez, Pilar Espinoza, Andrea Martínez, Marcela Arancibia, Harold Romero, Cecilia Bustamante, María Loreto Pérez, Natalia Uribe, Viviana Silva, Bernardita Morice, Marco Pérez, Marcela González, Werner Jensen, Claudia Pasten, M. Fernanda Aguilera, Nataly Martínez, Camila Molina, Sebastián Arrieta, Begoña López, Claudia Ortiz, Macarena Escobar, Camila Bustamante, Marcia Espinoza, Angela Pardo, Alison Carrasco, Miguel Montes, Macarena Saldías, Natalia Gutiérrez, Juliette Sánchez, Daniela Fuentes, Yolanda Calvo, Mariela Cepeda, Rosario Lemus, Muriel Suárez, Mercedes Armijo, Shirley Monsalves, Constance Marucich, Cecilia Cornejo, Ángela Acosta, Xaviera Prado, Francisca Yáñez, Marisol Barroeta, Claudia López, Paulina Donato, Martin Lasso, María Iturrieta, Juan Giraldo, Francisco Gutiérrez, María Acuña, Ada Cascone, Raymundo Rojas, Camila Sepúlveda, Mario Contreras, Yessica Campisto, Pablo González, Zoila Quizhpi, Mariella López, Vania Pizzeghello, Stephannie Silva

Publikováno v: EBioMedicine, Vol 91, Iss , Pp 104563- (2023)

Summary: Background: The Omicron variant has challenged the control of the COVID-19 pandemic due to its immuno-evasive properties. The administration of a booster dose of a SARS-CoV-2 vaccine showed positive effects in the immunogenicity against SARS

Externí odkaz: https://doaj.org/article/ada72f7a33e042e3b8078e201eaafcb4

Recognition of Variants of Concern by Antibodies and T Cells Induced by a SARS-CoV-2 Inactivated Vaccine

Autor: Felipe Melo-González, Jorge A. Soto, Liliana A. González, Jorge Fernández, Luisa F. Duarte, Bárbara M. Schultz, Nicolás M. S. Gálvez, Gaspar A. Pacheco, Mariana Ríos, Yaneisi Vázquez, Daniela Rivera-Pérez, Daniela Moreno-Tapia, Carolina Iturriaga, Omar P. Vallejos, Roslye V. Berríos-Rojas, Guillermo Hoppe-Elsholz, Marcela Urzúa, Nicole Bruneau, Rodrigo A. Fasce, Judith Mora, Alba Grifoni, Alessandro Sette, Daniela Weiskopf, Gang Zeng, Weining Meng, José V. González-Aramundiz, Pablo A. González, Katia Abarca, Eugenio Ramírez, Alexis M. Kalergis, Susan M. Bueno

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible of the current pandemic ongoing all around the world. Since its discovery in 2019, several circulating variants have emerged and some of them are associat

Externí odkaz: https://doaj.org/article/13f78279cb1a4b92aeac29dc13bff0ae

Global burden of acute lower respiratory infection associated with human metapneumovirus in children under 5 years in 2018: a systematic review and modelling study

Autor: Xin Wang, PhD, You Li, PhD, Maria Deloria-Knoll, PhD, Shabir A Madhi, ProfPhD, Cheryl Cohen, MD, Asad Ali, MD, Sudha Basnet, ProfMD, Quique Bassat, ProfMD, W Abdullah Brooks, MD, Malinee Chittaganpitch, MSc, Marcela Echavarria, PhD, Rodrigo A Fasce, BSc, Doli Goswami, MSc, Siddhivinayak Hirve, PhD, Nusrat Homaira, PhD, Stephen R C Howie, PhD, Karen L Kotloff, ProfMD, Najwa Khuri-Bulos, ProfMD, Anand Krishnan, ProfMD, Marilla G Lucero, MD, Socorro Lupisan, MD, Ainara Mira-Iglesias, MSc, David P Moore, PhD, Cinta Moraleda, PhD, Marta Nunes, PhD, Histoshi Oshitani, ProfMD, Betty E Owor, PhD, Fernando P Polack, ProfMD, Katherine L O'Brien, ProfMD, Zeba A Rasmussen, MD, Barbara A Rath, ProfMD, Vahid Salimi, PhD, J Anthony G Scott, ProfFRCP, Eric A F Simões, ProfMD, Tor A Strand, ProfPhD, Donald M Thea, ProfMD, Florette K Treurnicht, PhD, Linda C Vaccari, MbChB, Lay-Myint Yoshida, ProfPhD, Heather J Zar, ProfPhD, Harry Campbell, ProfMD, Harish Nair, ProfPhD, Romina Libster, Grieven Otieno, Imane Joundi, Shobha Broor, Mark Nicol, Ritvik Amarchand, Ting Shi, F. Xavier López-Labrador, Julia M. Baker, Alexandra Jamison, Avinash Choudekar, Sanjay Juvekar, Patrick Obermeier, Brunhilde Schweiger, Lola Madrid, Elizabeth Thomas, Miguel Lanaspa, Hanna Nohynek, James Nokes, Marta Werner, Anh Danhg, Mandeep Chadha, Joan Puig-Barberà, Mauricio T. Caballero, Maria Mathisen, Sibongile Walaza, Orienka Hellferscee, Matt Laubscher, Melissa M. Higdon, Meredith Haddix, Pongpun Sawatwong, Henry C. Baggett, Phil Seidenberg, Lawrence Mwanayanda, Martin Antonio, Bernard E. Ebruke, Tanja Adams, Mustafizur Rahman, Mohammed Ziaur Rahman, Samboa O. Sow, Vicky L. Baillie, Lesley Workman, Michiko Toizumi, Milagritos D. Tapia, Thi hien anh Nguyen, Susan Morpeth

Publikováno v: The Lancet Global Health, Vol 9, Iss 1, Pp e33-e43 (2021)

Summary: Background: Human metapneumovirus is a common virus associated with acute lower respiratory infections (ALRIs) in children. No global burden estimates are available for ALRIs associated with human metapneumovirus in children, and no licensed

Externí odkaz: https://doaj.org/article/4527be1f507e45a8aef2522ddddee038

Influenza vaccine effectiveness against hospitalizations in children and older adults—Data from South America, 2013–2017. A test negative design

Autor: Carmen Sofia Arriola, Nathalie El Omeiri, Eduardo Azziz-Baumgartner, Mark G. Thompson, Viviana Sotomayor-Proschle, Rodrigo A. Fasce, Martha Von Horoch, José Enrique Carrizo Olalla, Walquíria Aparecida Ferreira de Almeida, Jacqueline Palacios, Rakhee Palekar, Paula Couto, Miguel Descalzo, Alba María Ropero-Álvarez, Cecilia Gonzalez, Sergio Loayza, Natalia Vergara, Patricia Bustos, Winston Andrade, Carla Magda S. Domingues, Ernesto Issac Montenegro Renoiner, Érica Tatiane da Silva, Swamy Lima Palmeira, Daiana Araujo da Silva, Ana Carolina de Lacerda Sousa, Marilda Mendonça Siqueira, Cynthia Vazquez, Silvia Battaglia, Carla Vizzotti, Elsa Baumeister, Carlos Giovacchini, Nathalia Katz, Oscar Pacheco, Juliana Barbosa, Diana Malo, Paola Pulido, Diego Garcia, Consuelo Pinzón

Publikováno v: Vaccine: X, Vol 3, Iss , Pp - (2019)

Background: In 2013, the Pan American Health Organization established a multi-site, multi-country network to evaluate influenza vaccine effectiveness (VE). We pooled data from five consecutive seasons in five countries to conduct an analysis of south

Externí odkaz: https://doaj.org/article/8fa4a2959e6f41d5bf455d1b944f534c