Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rodrigo, Villagomez"'
Autor:
Grover Castañeta, Rodrigo Villagomez, Efrain Salamanca, Pamela Canaviri-Paz, José A. Bravo, José L. Vila, Daniela Bárcenas-Pérez, José Cheel, Beatriz Sepúlveda, Alberto Giménez, Carlos Areche
Publikováno v:
Separations, Vol 10, Iss 10, p 524 (2023)
Leishmaniasis is considered one of the most untreated tropical diseases in the world. In this study, we investigated the in vitro leishmanicidal activity and cytotoxicity of various isolated lichen substances, including atranorin (1), usnic acid (2),
Externí odkaz:
https://doaj.org/article/7d1a8e3081cc4035860246d34d894211
Autor:
Wendy Soria Sotillo, Rodrigo Villagomez, Sandra Smiljanic, Xiaoli Huang, Atena Malakpour, Sebastian Kempengren, Gloria Rodrigo, Giovanna Almanza, Olov Sterner, Stina Oredsson
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184304 (2017)
New regimens are constantly being pursued in cancer treatment, especially in the context of treatment-resistant cancer stem cells (CSCs) that are assumed to be involved in cancer recurrence. Here, we investigated the anti-cancer activity of sesquiter
Externí odkaz:
https://doaj.org/article/9c9fe5ef6cf54c52b2088de2557c3bc8
Autor:
Rodrigo Villagomez, Rajni Hatti-Kaul, Olov Sterner, Giovanna Almanza, Javier A Linares-Pastén
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0115819 (2015)
The nuclear factor κB (NF-κB) is a promising target for drug discovery. NF-κB is a heterodimeric complex of RelA and p50 subunits that interact with the DNA, regulating the expression of several genes; its dysregulation can trigger diverse disease
Externí odkaz:
https://doaj.org/article/42cc26eff3a1463dae32de22c2f53551
Autor:
Maribel Lozano, Wendy Soria, Giovanna R. Almanza, Sophie Manner, Stina Oredsson, Rodrigo Villagomez, Olov Sterner
Publikováno v:
Journal of Advanced Pharmaceutical Science And Technology. 2:23-37
Cancer is the leading cause of death worldwide, and there is a constant need for new treatment strategies. Sesquiterpene lactones containing a 3-methylenedihydrofuran-2(3H)-one (or a-methylene-g-lactone) moiety, for example damsin (1), are Michael ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26bc8d3c0ec7fc5fea528a0250ee9720
https://doi.org/10.14302/issn.2328-0182.japst-19-2759
https://doi.org/10.14302/issn.2328-0182.japst-19-2759
Publikováno v:
RSC advances. 11(20)
The enzymatic production of prebiotic xylooligosaccharides (XOS) has become an attractive way to valorise lignocellulosic biomass. However, despite numerous xylanases reported for potential use in the production of XOS, most of the family GH10 also p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab41d10bf2eb1606d638a03945a6b110
https://pubmed.ncbi.nlm.nih.gov/35423774
https://pubmed.ncbi.nlm.nih.gov/35423774
Microwave-Assisted Xylanase Reaction: The Impact in the Production of Prebiotic Xylooligosaccharides
The enzymatic production of prebiotic xylooligosaccharides (XOS) has become an attractive way to valorize lignocellulosic biomass. However, despite numerous xylanases reported for potential use in the production of XOS, most of the family GH10 also p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef54e2583760cac7e427ab1edf54cb47
https://doi.org/10.26434/chemrxiv.13401173.v1
https://doi.org/10.26434/chemrxiv.13401173.v1
Autor:
Olov Sterner, Maribel Lozano, Bengt-Olof Nilsson, Daniel Svensson, Rodrigo Villagomez, Giovanna R. Almanza
Publikováno v:
Phytomedicine. 50:118-126
Background Ambrosia arborescens has been used in Andean traditional medicine to reduce problems associated with various inflammatory diseases and conditions, although the underlying mechanism is unknown. Hypothesis/purpose The sesquiterpene lactones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f77eeedf9f3035d4fa0c69619059d07
https://doi.org/10.1016/j.phymed.2018.04.011
https://doi.org/10.1016/j.phymed.2018.04.011
Autor:
Samiullah Khan, Derek T. Logan, Sofia Lindahl, Rodrigo Villagomez, Tahir Mahmood, Javier A. Linares-Pastén, Eva Nordberg Karlsson, Tejas S. Kulkarni
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 85:872-884
The β-glucosidase TnBgl1A catalyses hydrolysis of O-linked terminal β-glycosidic bonds at the nonreducing end of glycosides/oligosaccharides. Enzymes with this specificity have potential in lignocellulose conversion (degrading cellobiose to glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3976a7a27b7d2db5ea0c7412fdcc4f6c
https://doi.org/10.1002/prot.25256
https://doi.org/10.1002/prot.25256
Autor:
Maribel Lozano, Wendy Soria, Giovanna R. Almanza, Sophie Manner, Stina Oredsson, Rodrigo Villagomez, Olov Sterner
As a follow-up of a previous investigation in which semisynthetic damsin derivatives were shown to possess up to 10 times higher cytotoxicity in JIMT-1 breast cancer cells compared to normal breast epithelial MCF-10A cells, a range of new derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d002897fd42c8dab376c7bf84eac0c1
Publikováno v:
Chemistry of Natural Compounds. 51:675-680
Damsin (1) is a pseudoguaianolide sesquiterpene possessing potent biological activities, reported as a metabolite of several medicinal plants belonging to the genus Ambrosia together with related compounds. Starting from 1, which can be isolated in g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b22eab9906cb57ba589709015238b34
https://doi.org/10.1007/s10600-015-1382-9
https://doi.org/10.1007/s10600-015-1382-9